Results 71 to 80 of about 693,970 (340)
Cells must clear mislocalized or faulty proteins from membranes to survive. The AAA+ ATPase Msp1 performs this task, but dissecting how its six subunits work together is challenging. We engineered linked dimers with varied numbers of functional subunits to reveal how Msp1 subunits cooperate and use energy to extract proteins from the lipid bilayer ...
Deepika Gaur +5 more
wiley +1 more source
CCT4 promotes tunneling nanotube formation
Tunneling nanotubes (TNTs) are membranous tunnel‐like structures that transport molecules and organelles between cells. They vary in thickness, and thick nanotubes often contain microtubules in addition to actin fibers. We found that cells expressing monomeric CCT4 generate many thick TNTs with tubulin.
Miyu Enomoto +3 more
wiley +1 more source
A Dozen Problems, Questions and Conjectures About Positive Scalar Curvature [PDF]
Unlike manifolds with positive sectional and with positive Ricci curvatures which aggregate to modest (roughly) convex islands in the vastness of all Riemannian spaces, the domain \(\{\mathcal{SC}>0\}\) of manifolds with positive scalar curvatures ...
M. Gromov
semanticscholar +1 more source
Volume comparison with respect to scalar curvature [PDF]
In this article, we investigate the volume comparison with respect to scalar curvature. In particular, we show volume comparison hold for small geodesic balls of metrics near $V$-static metrics.
Wei Yuan
semanticscholar +1 more source
Critical metrics of the $L^2$-norm of the scalar curvature
In this paper we investigate complete critical metrics of the $L^{2}$-norm of the scalar curvature. We prove that any complete critical metric with positive scalar curvature has constant scalar curvature and we characterize critical metrics with ...
Catino, Giovanni
core +1 more source
Anaplastic thyroid cancer (ATC) lacks iodide uptake ability due to MAPK activation increasing the expression of the histone methyltransferase EZH2, which represses thyroid differentiation genes (TDGs) such as the sodium iodide symporter (NIS). Dual inhibition of MAPK (U0126) and EZH2 (EPZ6438/Tazemetostat) reverses this mechanism, thus restoring TDG ...
Diego Claro de Mello +6 more
wiley +1 more source
Remarks on a result of Chen-Cheng
In their seminal work, Chen and Cheng proved a priori estimates for the constant scalar curvature metrics on compact Kähler manifolds. They also prove C3,α{C}^{3,\alpha }-estimate for the potential of the Kähler metrics under boundedness assumption on ...
Lu Zhiqin, Seyyedali Reza
doaj +1 more source
Disformal transformation of cosmological perturbations
We investigate the gauge-invariant cosmological perturbations in the gravity and matter frames in the general scalar–tensor theory where two frames are related by the disformal transformation.
Masato Minamitsuji
doaj +1 more source
Isoperimetry, Scalar Curvature, and Mass in Asymptotically Flat Riemannian 3‐Manifolds [PDF]
Let (M, g) be an asymptotically flat Riemannian 3‐manifold with nonnegative scalar curvature and positive mass. We show that each leaf of the canonical foliation of the end of (M, g) through stable constant mean curvature spheres encloses more volume ...
Otis Chodosh +3 more
semanticscholar +1 more source
A theorem for the existence of solutions of the nonlinear elliptic equation − Δ u + 2 = R ( x ) e u , x ∈ S 2 - \Delta u + 2 = R(x){e^u},\;x \in ...
Wen Xiong Chen, Wei Yue Ding
openaire +1 more source

