Results 71 to 80 of about 676,684 (291)

Scalar field wormholes

open access: yesNuclear Physics B, 1989
Abstract A classical wormhole solution is constructed for gravity couples to a positive energg, maplese scalar field. We examine carefully the definitions of euclideanization, and find that this solution is equivalent to the wormhole previously obtained for gravity coupled to an antisymmetric, two-index gauge potential, which is locally dual to the ...
J.D. Brown   +4 more
openaire   +1 more source

Massless Scalar QED with Non-minimal Chern Simons Coupling

open access: yes, 1993
2+1 dimensional massless scalar QED with $(\phi^*\phi)^3$ scalar self-coupling is modified by the addition of a non- minimal Chern-Simons term that couples the dual of the electromagnetic field strength to the covariant current of the complex scalar ...
A. Fetter   +23 more
core   +2 more sources

Minimal Extension of the Standard Model Scalar Sector [PDF]

open access: yes, 2006
The minimal extension of the scalar sector of the standard model contains an additional real scalar field with no gauge quantum numbers. Such a field does not couple to the quarks and leptons directly but rather through its mixing with the standard model
Donal O’Connell   +4 more
core   +2 more sources

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

open access: yesMolecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson   +2 more
wiley   +1 more source

Instability of Massive Scalar Fields in Kerr-Newman Spacetime

open access: yes, 2004
We investigate the instability of charged massive scalar fields in Kerr-Newman spacetime. Due to the super-radiant effect of the background geometry, the bound state of the scalar field is unstable, and its amplitude grows in time.
Furuhashi, Hironobu, Nambu, Yasusada
core   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

open access: yesMolecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed   +10 more
wiley   +1 more source

Bulk scalar field in DGP braneworld cosmology

open access: yes, 2007
We investigated the effects of bulk scalar field in the braneworld cosmological scenario. The Friedmann equations and acceleration condition in presence of the bulk scalar field for a zero tension brane and cosmological constant are studied. In DGP model
Aoyanagi H   +5 more
core   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

Quintessence and phantom emerging from the split-complex field and the split-quaternion field

open access: yes, 2015
Motivated by the mathematic theory of split-complex numbers (or hyperbolic numbers, also perplex numbers) and the split-quaternion numbers (or coquaternion numbers), we define the notion of split-complex scalar field and the split-quaternion scalar field.
Chen, Xuelei   +2 more
core   +1 more source

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