Rate and cost of adaptation in the Drosophila Genome
, 2014 Recent studies have consistently inferred high rates of adaptive molecular evolution between Drosophila species. At the same time, the Drosophila genome evolves under different rates of recombination, which results in partial genetic linkage between ...
Lässig, Michael +2 more
core +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Stigma Scale Adaptation and Validation for Measuring COVID-19 Stigma. [PDF]
Cureus, 2023 Pallavi P +4 more
europepmc +1 more source
Portuguese Adaptation of Students' Engagement in Schools International Scale (SESIS) [PDF]
, 2012 This work is financed by National Founds through FCT - Fundação para a Ciência e Tecnologia, in the context of the project PTDC/CPE-CED/114362/2009- Students Engagement in Schools: Differentiation and Promotion, coordinated by Prof. Feliciano H.
Almeida, Ana +12 more
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Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Validation of Hospital Anxiety and Depression Scale in an Indonesian population: a scale adaptation study. [PDF]
Fam Med Community Health, 2023 Tiksnadi BB +5 more
europepmc +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
MeritsThe present study evaluated the empirical distinction between the PERMA-Profiler and the Workplace PERMA-Profiler, which measure flourishing using the same items with different contexts (i.e., general vs. workplace orientations).
Sean P. M. Rice
doaj +1 more source
Portuguese version of Bern Illegitimates Task Scale: adaptation and evidence of validity. [PDF]
BMC Psychol, 2023 Neves PC +3 more
europepmc +1 more source
Ecosystem-based adaptation for smallholder farmers in agricultural landscapes in Central America: opportunities and constraints [PDF]
, 2014 It is increasingly recognized that climate change will have a disproportionate impact on smallholder farmers, due to their dependence on agriculture for both livelihoods and food security, their often high levels of poverty, location in remote areas and ...
Alpizar, Francisco +8 more
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