Results 51 to 60 of about 1,079,684 (305)

Spatial fluctuations at vertices of epithelial layers: quantification of regulation by Rho pathway [PDF]

open access: yes, 2018
In living matter, shape fluctuations induced by acto-myosin are usually studied in vitro via reconstituted gels, whose properties are controlled by changing the concentrations of actin, myosin and cross-linkers.
Comelles, J.   +7 more
core   +1 more source

Health‐Related Quality of Life and Symptom Severity Among Patients With PIK3CA‐Related Overgrowth Spectrum: A Mixed‐Methods Study to Understand Real‐World Experience With Alpelisib Treatment

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background PIK3CA‐related overgrowth spectrum (PROS) includes several rare overgrowth disorders resulting from somatic gain‐of‐function mutations in PIK3CA. Despite treatment advances, including the recent approval of alpelisib for PROS in the United States, literature detailing the patient experience with PROS is limited.
Vamsi Bollu   +8 more
wiley   +1 more source

Perspective: network-guided pattern formation of neural dynamics [PDF]

open access: yes, 2014
The understanding of neural activity patterns is fundamentally linked to an understanding of how the brain's network architecture shapes dynamical processes.
Hilgetag, Claus C.   +2 more
core   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Modelling crystal aggregation and deposition\ud in the catheterised lower urinary tract [PDF]

open access: yes, 2009
Urethral catheters often become encrusted with crystals of magnesium struvite and calcium phosphate. The encrustation can block the catheter, which can cause urine retention in the bladder and reflux into the kidneys.
Band, L. R.   +3 more
core  

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Study on synthesis and properties of environmental protection water treatment agent [PDF]

open access: yesE3S Web of Conferences
The copolymers were obtained by a water-based polymerization reaction using maleic anhydride and acrylic acid as the main raw materials. And the scale inhibition performance of the resulting scale inhibitor was investigated by static scale inhibition ...
Liu Zhan   +5 more
doaj   +1 more source

Nanosilica modified with polyaspartic acid as an industrial circulating water scale inhibitor

open access: yesnpj Clean Water, 2021
Given the special performance of nanosilica with its small size, large specific surface area and high surface activity, nanosilica containing reactive amino group (denoted as SiO2–NH2) and polysuccinimide were allowed to take part in polymerization ...
Yamin Cheng   +6 more
doaj   +1 more source

Optimization and Performance Evaluation of Foam Discharge Agent for Deep Aquatic Condensate Gas Well

open access: yesFrontiers in Physics, 2022
The block deep condensate gas reservoir in the basin in the southeast of the South China Sea is a bottom water reservoir and is producing in the late effusion, which faces problems such as scaling, condensate oil–water two-phase flow, and low temperature
Lei Ge   +3 more
doaj   +1 more source

Structure-based inhibitors of amyloid beta core suggest a common interface with tau. [PDF]

open access: yes, 2019
Alzheimer's disease (AD) pathology is characterized by plaques of amyloid beta (Aβ) and neurofibrillary tangles of tau. Aβ aggregation is thought to occur at early stages of the disease, and ultimately gives way to the formation of tau tangles which ...
Bowler, Jeannette   +13 more
core   +1 more source

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