Results 81 to 90 of about 939,708 (316)
Molecular Oncology, EarlyView.Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source
Comparing parameter choice methods for regularization of ill-posed problems
, 2011 In the literature on regularization, many different parameter choice methods have been proposed in both deterministic and stochastic settings. However, based on the available information, it is not always easy to know how well a particular method will ...
Bauer, F., Lukas, M.A.
core
Development and application of a soil classification-based conceptual catchment- scale hydrological model [PDF]
, 2005 A conceptual, continuous, daily, semi distributed catchment-scale rainfall- runoff model that has the potential to be ultimately used in ungauged catchments is described.
Holman, Ian P., Marechal, David
core +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens +6 more
wiley +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Shrinkage Estimators for the Exponential Scale Parameter under Multiply Type II Censoring
Austrian Journal of Statistics, 2016 We consider the problem of estimating the scale parameter of an exponential distribution under multiply type II censoring when a prior point guess of the parameter value is available.
Umesh Singh, Anil Kumar
doaj +1 more source
Implementation of the Simple Hyperchaotic Memristor Circuit with Attractor Evolution and Large-Scale Parameter Permission. [PDF]
Entropy (Basel), 2023 Yang G, Zhang X, Moshayedi AJ.
europepmc +1 more source
Posterior moments of scale parameters in elliptical regression models. [PDF]
In the general multivariate elliptical class of data densities we define a scalar precision parameter r through a normalization of the scale matrix V. Using the improper prior on r which preserves the results under Normality for all other parameters and ...
Osiewalski, Jacek, Steel, Mark F.J.
core
Towards large scale continuous EDA: a random matrix theory perspective
, 2013 Estimation of distribution algorithms (EDA) are a major branch of evolutionary algorithms (EA) with some unique advantages in principle. They are able to take advantage of correlation structure to drive the search more efficiently, and they are able to ...
Kabán, Ata +5 more
core +1 more source