Results 71 to 80 of about 939,708 (316)
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Hypothesis tests on the scale parameter using median ranked set sampling
In this paper, some test procedures for scale parameters of exponential and rectangular distributions involving the median ranked set sampling (MRSS) method are discussed. The necessary tables for the critical regions for the suggested tests are supplied.
Syed S. Hossain, Hassen A. Muttlak
doaj +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Sequential Point Estimation of a Function of the Exponential Scale Parameter
We consider sequential point estimation of a function of the scale parameter of an exponential distribution subject to the loss function given as a sum of the squared error and a linear cost.
Chikara Uno +2 more
doaj +1 more source
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Sequential point and interval estimation of scale parameter of exponential distribution
Sequential fixed-width confidence intervals are obtained for the scale parameter σ when the location parameter θ of the negative exponential distribution is unknown.
Z. Govindarajulu
doaj +1 more source
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Biomechanical parameter assessment for classification of Parkinson’s disease on clinical scale
The primary goal of this study was to investigate computerized assessment methods to classify motor dysfunctioning of patients with Parkinson’s disease on the clinical scale. In this proposed system, machine learning–based computerized assessment methods
Abdul Haleem Butt +5 more
doaj +1 more source
Parameter Analysis in Macro-Scale Molecular Communications Using Advection-Diffusion
Molecular communication (MC) is a method where the transmission of information involves the use of chemicals or molecules instead of electromagnetic waves.
Daniel Tunc McGuiness +3 more
doaj +1 more source
Scale-Dependent Optimized Homoepitaxy of InAs(111)A
We combined in situ scanning tunneling microscopy (STM) with the conventional growth characterization methods of atomic force microscopy (AFM) and reflection high-energy electron diffraction (RHEED) to simultaneously assess atomic scale impurities and ...
Derek Dardzinski (13530152) +5 more
core +1 more source

