Results 61 to 70 of about 915,441 (269)

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Hypothesis tests on the scale parameter using median ranked set sampling

open access: yesStatistica, 2008
In this paper, some test procedures for scale parameters of exponential and rectangular distributions involving the median ranked set sampling (MRSS) method are discussed. The necessary tables for the critical regions for the suggested tests are supplied.
Syed S. Hossain, Hassen A. Muttlak
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Sequential Point Estimation of a Function of the Exponential Scale Parameter

open access: yesAustrian Journal of Statistics, 2016
We consider sequential point estimation of a function of the scale parameter of an exponential distribution subject to the loss function given as a sum of the squared error and a linear cost.
Chikara Uno   +2 more
doaj   +1 more source

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

open access: yesFEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui   +4 more
wiley   +1 more source

Sequential point and interval estimation of scale parameter of exponential distribution

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 1995
Sequential fixed-width confidence intervals are obtained for the scale parameter σ when the location parameter θ of the negative exponential distribution is unknown.
Z. Govindarajulu
doaj   +1 more source

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Biomechanical parameter assessment for classification of Parkinson’s disease on clinical scale

open access: yesInternational Journal of Distributed Sensor Networks, 2017
The primary goal of this study was to investigate computerized assessment methods to classify motor dysfunctioning of patients with Parkinson’s disease on the clinical scale. In this proposed system, machine learning–based computerized assessment methods
Abdul Haleem Butt   +5 more
doaj   +1 more source

Parameter Analysis in Macro-Scale Molecular Communications Using Advection-Diffusion

open access: yesIEEE Access, 2018
Molecular communication (MC) is a method where the transmission of information involves the use of chemicals or molecules instead of electromagnetic waves.
Daniel Tunc McGuiness   +3 more
doaj   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

open access: yesFEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

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