Results 81 to 90 of about 5,116,539 (328)
PLoS Genetics, 2015 Despite the success of genome-wide association studies in medical genetics, the underlying genetics of many complex diseases remains enigmatic. One plausible reason for this could be the failure to account for the presence of genetic interactions in ...
Mattias Frånberg +5 more
doaj +1 more source
Supersymmetric AdS vacua and separation of scales [PDF]
, 2012 The moduli space of the supersymmetric massive IIA AdS4xS2(B4) vacua, where S2(B4) is a two-sphere bundle over a four-dimensional Kaehler-Einstein base B4, includes three independent parameters which can be thought of as corresponding to the sizes of ...
A Tomasiello +17 more
core +4 more sources
Neutrophil deficiency increases T cell numbers at the site of tissue injury in mice
FEBS Letters, EarlyView.In wild‐type mice, injury or acute inflammation induces neutrophil influx followed by macrophage accumulation. Mcl1ΔMyelo (neutrophil‐deficient) mice lack neutrophils, and in response to muscle injury show fewer macrophages and exhibit strikingly elevated T‐cell numbers, primarily non‐conventional “double‐negative” (DN) αβ and γδ T cells.
Hajnalka Halász +6 more
wiley +1 more source
The stationary phase point method for transitional scattering: diffractive radio scintillation for pulsar [PDF]
, 2007 The stationary phase point (SPP) method in one-dimensional case is introduced to treat the diffractive scintillation. From weak scattering, where the SPP number N=1, to strong scattering (N$\gg$1), via transitional scattering regime (N$\sim$2,3), we find
Blandford R D +13 more
core +2 more sources
Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells
FEBS Letters, EarlyView.Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan +2 more
wiley +1 more source
Frontiers in Bioengineering and BiotechnologyRecent research has focused on issues related to contamination, nutrient availability, and strain selection, but there has been insufficient focus on harvesting research.
Hooi Ren Lim +3 more
doaj +1 more source
FEBS Letters, EarlyView.The Arabidopsis mutants hls1 hlh1 and amp1 lamp1 exhibit pleiotropic developmental phenotypes. Although the functions of the causative genes remain unclear, they act in the same genetic pathway and are thought to generate non‐cell‐autonomous signals.
Takashi Nobusawa, Makoto Kusaba
wiley +1 more source
FEBS Letters, EarlyView.Spinal muscular atrophy (SMA) is a genetic disease affecting motor neurons. Individuals with SMA experience mitochondrial dysfunction and oxidative stress. The aim of the study was to investigate the effect of an antioxidant and neuroprotective substance, ergothioneine (ERGO), on an SMNΔ7 mouse model of SMA.
Francesca Cadile +8 more
wiley +1 more source
Microbial exopolysaccharide production by polyextremophiles in the adaptation to multiple extremes
FEBS Letters, EarlyView.Polyextremophiles are microorganisms that endure multiple extreme conditions by various adaptation strategies that also include the production of exopolysaccharides (EPSs). This review provides an integrated perspective on EPS biosynthesis, function, and regulation in these organisms, emphasizing their critical role in survival and highlighting their ...
Tracey M Gloster, Ebru Toksoy Öner
wiley +1 more source
Large Scale Fluctuations in an Axisymmetric Sudden Pipe Expansion with Large Aspect Ratio
Journal of Applied Fluid Mechanics, 2018 The aim of the present work is the investigation of the turbulent flow field downstream of an axisymmetric sudden expansion with a large aspect ratio of D/d = 12,3.
A. Ringleb +3 more
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