Results 151 to 160 of about 3,018,546 (285)

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Amharic version of the work-life balance scale: validation and psychometric properties. [PDF]

BMC Psychol
Teshome W, Tefera D, Demlie D, Teklu H, Fikadu Y.   +4 more
europepmc   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

A short mental health literacy scale: validation and application in Brazil. [PDF]

BMC Public Health
Buta BO, Couto VVD, Froner MB, Tabak BM.
europepmc   +1 more source

Adherence to treatment and harmful effects of medication shortages in the context of severe crises: scale validation and correlates. [PDF]

J Pharm Policy Pract, 2023
Bou Malhab S, Haddad C, Sacre H, Hajj A, Zeenny RM, Akel M, Salameh P.   +6 more
europepmc   +1 more source

Validation of mathematical manoeuvring models by full scale measurements [PDF]

, 2015
Delefortrie, Guillaume, Eloot, Katrien, Vantorre, Marc, Verwilligen, Jeroen, Vos, Stijn   +4 more
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Italian Technostress Creators Scale: Validation of an Assessment Tool. [PDF]

J Occup Environ Med
Rossi MF, Beccia F, Iantorno F, Melcore G, Gualano MR, Moscato U.   +5 more
europepmc   +1 more source

Better characterizing sleep beliefs for personalized sleep health promotion: the French sleep beliefs scale validation study. [PDF]

Front Public Health, 2023
Coelho J, Rey M, Labonne A, Adan A, Taillard J, Geoffroy PA, Cugy D, Dakar A, Philip P, Poirot I, Royant-Parola S, Hartley S, Vecchierini MF, Micoulaud-Franchi JA.   +13 more
europepmc   +1 more source