Results 51 to 60 of about 397,310 (297)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

High resolution atomic force and Kelvin probe force microscopy image data of InAs(001) surface using frequency modulation method

Data in Brief, 2020
This article provides data on the scanning tunnelling microscopy (STM), atomic force microscopy (AFM) and Kelvin probe force microscopy (KPFM) images of InAs(001) surface.
Young Min Park, Joon Sik Park, Choong-Heui Chung, Sangyeob Lee   +3 more
doaj   +1 more source

Thermoresponsive Colloidal Molecules

, 2010
We fabricated thermoresponsive colloidal molecules of ca. 250 nm size. Electron- and scanning force microscopy reveal the dumbbell-shaped morphology. The temperature dependence of the size and aspect ratio (ca.
Ballauff, Matthias, Drechsler, Markus, Hanske, Christoph, Harnau, Ludger, Hoffmann, Martin, Hund, Markus, Lu, Yan, Siebenbuerger, Miriam, Wagner, Claudia S.   +8 more
core   +1 more source

Local spectroscopy and atomic imaging of tunneling current, forces and dissipation on graphite [PDF]

, 2005
Theory predicts that the currents in scanning tunneling microscopy (STM) and the attractive forces measured in atomic force microscopy (AFM) are directly related. Atomic images obtained in an attractive AFM mode should therefore be redundant because they
C. F. Quate, F. J. Giessibl, G. A. Tomlinson, H. Hölscher, H. J. Hug, J. Mannhart, L. Prandtl, S. Hembacher   +7 more
core   +2 more sources

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Atomic Force Microscopy and Scanning Ion-Conductance Microscopy for Investigation of Biomechanical Characteristics of Neutrophils

Cells
Scanning probe microscopy (SPM) is a versatile tool for studying a wide range of materials. It is well suited for investigating living matter, for example, in single-cell neutrophil studies.
Mikhail Shvedov, Ekaterina Sherstyukova, Snezhanna Kandrashina, Vladimir Inozemtsev, Viktoria Sergunova   +4 more
doaj   +1 more source

Interaction imaging with amplitude-dependence force spectroscopy

, 2013
Knowledge of surface forces is the key to understanding a large number of processes in fields ranging from physics to material science and biology. The most common method to study surfaces is dynamic atomic force microscopy (AFM).
A San Paulo, AC Hindmarsh, AJ Katan, B Luan, BJ Albers, BV Derjaguin, D Platz, EA Tholén, F Jamitzky, FJ Giessibl, H Hölscher, H Hölscher, HJ Mamin, IN Sneddon, J Legleiter, J Melcher, J Melcher, JE Sader, JL Arlett, JP Cleveland, K Jensen, L Mininni, M Dong, M Lee, M Li, M Stark, MD LaHaye, MJ Higgins, MT Cuberes, MZ Baykara, O Sahin, O Sahin, R Garcia, R Garcia, RW Stark, S Basak, S Hu, S Hu, S Jesse, S Walheim, U Dürig, U Dürig, Y Seo   +42 more
core   +1 more source

Magnetization reversal in mesoscopic Ni80Fe20 wires: A magnetic domain launching device [PDF]

, 2000
The magnetization reversal process in mesoscopic permalloy (Ni80Fe20) wire structures has been investigated using scanning Kerr microscopy, magnetic force microscopy (MFM) and micromagnetic calculations.
Bland, J.A.C., Gardiner, S.M., Guertler, C.M., Hirohata, A., Lee, W.Y., Leung, H.T., Xu, Y.B., Yao, C.C.   +7 more
core   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Preparation of (Pb,Ba)TiO3 powders and highly oriented thin films by a sol-gel process [PDF]

, 2003
Solid solution Pb1-xBaxTiO3, with particular emphasis on Pb0.5Ba0.5TiO3, was prepared using a sol-gel process incorporating lead acetate trihydrate, barium acetate, and titanium isopropoxide as precursors, acetylacetone (2,4 pentanedione) as a chelating ...
Boland, Stacey W., Haile, Sossina M., Pillai, Suresh C., Yang, Wein-Duo   +3 more
core   +3 more sources