Results 61 to 70 of about 782,566 (296)

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

ON FATIGUE LIFE SCATTER FACTOR FOR THE AIRCRAFT STRUCTURE

open access: yesJixie qiangdu, 2016
The fatigue life scatter factor is an important reliability index of the assessment of aircraft fatigue life. At present,the safe-life of a fleet is gotten by using the total test hours and the fatigue scatter factor.
GAO Chao, HE YuTing, HOU Bo, ZHANG Teng
doaj  

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

Investigation of grid performance using simple image quality tests

open access: yesJournal of Medical Physics, 2016
Antiscatter grids improve the X-ray image contrast at a cost of patient radiation doses. The choice of appropriate grid or its removal requires a good knowledge of grid characteristics, especially for pediatric digital imaging. The aim of this work is to
Dogan Bor   +3 more
doaj   +1 more source

Form factors for meson-kink scattering

open access: yesPhysics Letters B, 2022
We calculate the leading quantum corrections to the meson form factors of nonrelativistic kinks, at momentum transfer much higher than the meson mass. We consider general scalar theories which need not be integrable. Our approach is much simpler than previous approaches, avoiding any need for counterterms, ordering ambiguities and nonlinear canonical ...
openaire   +3 more sources

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Physiological Signaling and Structure of the HGF Receptor MET

open access: yesBiomedicines, 2014
The “hepatocyte growth factor” also known as “scatter factor”, is a multifunctional cytokine with the peculiar ability of simultaneously triggering epithelial cell proliferation, movement and survival.
Gianluca Baldanzi, Andrea Graziani
doaj   +1 more source

Universality of Soft and Collinear Factors in Hard-Scattering Factorization [PDF]

open access: yesPhysical Review Letters, 2004
4 pages. Extra references.
Collins, John C., Metz, Andreas
openaire   +3 more sources

Breaks in surface brightness profiles and radial abundance gradients in the discs of spiral galaxies

open access: yes, 2017
We examine the relation between breaks in the surface brightness profiles and radial abundance gradients within the optical radius in the discs of 134 spiral galaxies from the CALIFA survey. The distribution of the radial abundance (in logarithmic scale)
Grebel, E. K   +4 more
core   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

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