The Technical Feasibility of Digital Spatial Profiling in Immune/Inflammation Study of Thrombosis
Jianjun Jiang, Yang Liu Department of General Surgery, Vascular Surgery, Qilu Hospital of Shandong University, Jinan, Shandong, People’s Republic of ChinaCorrespondence: Yang Liu, Department of General Surgery, Vascular Surgery, Qilu Hospital of Shandong
Jiang J, Liu Y
doaj
Free Radical Scavenging and Cytotoxic Activities of Substituted Pyrimidines [PDF]
A library of substituted pyrimidines was synthesized and evaluated for free radical scavenging, and in vitro cytotoxic activity in 3T3 cells. All compounds showed good free radical scavenging activity with IC50 values in the range of 42.9 + 0.31 to 438.3 3.3 {\mu}M as compared to the standard butylated hydroxytoluene having IC50 value of 128.83 2.
arxiv
Mechanical and Light Activation of Materials for Chemical Production
The actuation of stomata—referring to their opening and closing—is crucial for photosynthesis because it regulates gas exchange and water balance. Here, it is investigated if this life‐like property could enhance the photocatalytic properties of soft materials.
Luka Đorđević+7 more
wiley +1 more source
Multiple Routes for Glutamate Receptor Trafficking: Surface Diffusion and Membrane Traffic Cooperate to Bring Receptors to Synapses [PDF]
Trafficking of glutamate receptors into and out of synapses is critically involved in the plasticity of excitatory synaptic transmission. Endocytosis and exocytosis of receptors have initially been thought to account alone for this trafficking. However, membrane proteins also traffic through surface lateral diffusion in the plasma membrane. We describe
arxiv
Scavenger Receptor A: A New Route for Adenovirus 5
Adenoviruses are common pathogens associated with respiratory diseases, gastrointestinal illnesses and/or conjunctivitis. Currently, this virus is used as a vector in gene therapy trials. The promise of viral gene therapy applications is substantially reduced because the virus is cleared by liver macrophages upon systemic administration.
Haisma, H+7 more
openaire +3 more sources
Photo‐Induced Bandgap Engineering of Metal Halide Perovskite Quantum Dots In Flow
This work presents a photochemical synthetic route for bandgap engineering of metal halide perovskite quantum dots. Utilizing a material‐efficient microfluidic platform, the underlying mechanism of the photo‐induced anion exchange reaction (PIAER) of metal halide perovskite quantum dots is unveiled and first instance of the PIAER‐enabled synthesis of ...
Pragyan Jha+9 more
wiley +1 more source
Lipoprotein receptor interactions are not required for monocyte oxidation of LDL.
Upon activation, human peripheral blood monocytes and U937 cells oxidized low density lipoprotein (LDL), converting it to a cytotoxin. The oxidized LDL loses its ability to interact specifically with the native LDL (apoB/E) receptor and becomes a ligand ...
M K Cathcart, Q Li, G M Chisolm, 3rd
doaj
Ligand Binding and Signaling of HARE/Stabilin-2
The Stabilin receptors are a two-member family in the type H class of scavenger receptors. These dynamic receptors bind and internalize multiple ligands from the cell surface for the purpose of clearing extracellular material including some synthetic ...
Edward N. Harris, Fatima Cabral
doaj +1 more source
Materials Advances in Devices for Heart Disease Interventions
This review examines the crucial role of materials in heart disease interventions, focusing on strategies for monitoring, managing, and repairing heart conditions. It discusses the material requirements for medical devices, highlighting recent innovations and their impact on cardiovascular health.
Gagan K. Jalandhra+11 more
wiley +1 more source
Scavenger receptor class B type I as a receptor for oxidized low density lipoprotein
Scavenger receptor class B type I (SR-BI) has been established as the primary mediator of the selective transfer of lipids from HDL to mammalian cells.
Kristin Gillotte-Taylor+4 more
doaj