Results 311 to 320 of about 2,493,460 (390)

Anti-JNK2 peptide–siRNA nanostructures improve plaque endothelium and reduce thrombotic risk in atherosclerotic mice [PDF]

, 2018
Akk, Antonina, Bacon, John, Hou, Kirk K, Miller, Mark J, Palekar, Rohun U, Pan, Hua, Pham, Christine T.N, Schlesinger, Paul H, Springer, Luke E, Wickline, Samuel A, Yan, Huimin, Yang, Lihua   +11 more
core   +1 more source

Biomimetic Organic Nanozyme as Tumor Vaccines for Targeted Suppression of Ammonia‐Induced T Lymphocyte Death to Augment Breast Cancer Immunotherapy

Advanced Science, EarlyView.
The organic nanozyme IR‐IHpd, which has NIR‐PDT and POD‐like activity, is designed for continuous ROS generation. It is co‐encapsulated with CB‐839 and coated with DC membranes to simultaneously target tumors and T cells. Under NIR irradiation, immunogenic cell death is activated. Concurrently, CB‐839 suppresses ammonia‐induced T lymphocyte death (AITD)
Meng Suo, Deyi Yang, Mingpu Yang, Jue Wang, Dingfeng Zhang, Daoming Zhu, Qingyong Xu, Yanni Song   +7 more
wiley   +1 more source

A co-assembly platform engaging macrophage scavenger receptor A for lysosome-targeting protein degradation. [PDF]

Nat Commun
Wang Q, Yang X, Yuan R, Shen A, Wang P, Li H, Zhang J, Tian C, Jiang Z, Li W, Dong S.   +10 more
europepmc   +1 more source

Scavenger receptor for aldehyde-modified proteins.

, 1986
Seikoh Horiuchi, Masaji Murakami, Kazuhide Takata, Yoshimasa Morino   +3 more
openalex   +1 more source

Iron Oxide Nanozyme as Reactive Oxygen and Nitrogen Species Scavenger to Regulate Microglial Homeostasis in Stroke

Advanced Science, EarlyView.
6 nm iron oxide nanoparticles (IONP6) exhibit enzyme‐like activities that scavenge reactive oxygen and nitrogen species (RONS), including nitric oxide (NO). In stroke models, IONP6 promotes microglial polarization toward the M2 phenotype, reduces neuroinflammation, and improves neurological outcomes, offering a promising drug‐free approach to mitigate ...
Yilin Qi, Chunxiao Wang, Yuqing Miao, Jiamin Li, Zengyu Xun, Di Sun, Fei Xu, Minrui Liu, Heping Wang, Galong Li, Xuyi Chen, Haiming Fan, Xue Xue   +12 more
wiley   +1 more source

Encapsulation and Delivery of the Kinase Inhibitor PIK-75 by Organic Core High-Density Lipoprotein-Like Nanoparticles Targeting Scavenger Receptor Class B Type 1. [PDF]

ACS Appl Mater Interfaces
Rink JS, Lin AY, Calvert AE, Kwon D, Moxley A, Henrich SE, Mohammadlou A, Zhang XH, Wu X, Querfeld C, Griend DJV, Yin HH, Horne DA, Nguyen ST, Rosen ST, Gordon LI, Thaxton CS.   +16 more
europepmc   +1 more source

Scavenger receptors of macrophages.

Journal of the Japan Society of the Reticuloendothelial System, 1993
openaire   +2 more sources

Constitutive Death of Platelets Leading to Scavenger Receptor-mediated Phagocytosis

, 2000
Simon Brown, Murray C.H. Clarke, Lorna Magowan, H. M. Sanderson, John Savill   +4 more
openalex   +1 more source

Chaperone‐Mediated Autophagic Degradation of USP9X in Macrophages Exacerbates Postmyocardial Infarction Inflammation and Cardiac Dysfunction

Advanced Science, EarlyView.
This study demonstrates that inflammatory stimuli induce the acetylation‐triggered, chaperone‐mediated autophagic degradation of ubiquitin‐specific peptidase 9 X‐linked (USP9X) in macrophages. USP9X acts as a macrophage “inflammation switch” after myocardial infarction (MI). USP9X loss destabilizes tumor necrosis factor receptor‐associated factor (TRAF)
Biqing Wang, Xiangheng Cai, Mengqi Li, Xue Liu, Junhui Xue, Ye Liu, Ding Ai, Xinyang Hu   +7 more
wiley   +1 more source

CsdA‐LaeB Regulatory Hub Contributes to Aspergillus fumigatus Virulence via Fumiquinazoline C Biosynthesis

Advanced Science, EarlyView.
This study identifies a conserved CsdA‐LaeB hub in Aspergillus fumigatus that regulates secondary metabolite fumiquinazoline C (FqC). Disrupting this hub enhances FqC production and virulence, shedding new light on the post‐transcriptional regulatory logic linking secondary metabolism to pathogenicity and offering alternative strategies for diagnostic ...
Zili Song, Hongjiao Zhang, Leixin Ye, Yuxin Lei, Linqi Wang, Xiao Liu, Nayanna M. Mercado Soto, Nancy P. Keller, Berl R. Oakley, Can Zhao, Michael Bromley, Hongwei Liu, Lei Cai, Koon Ho Wong, Wen‐Bing Yin   +14 more
wiley   +1 more source