Results 131 to 140 of about 103,100 (354)

Sprouty2 loss‐induced IL6 drives castration‐resistant prostate cancer through scavenger receptor B1 [PDF]

, 2018
Metastatic castration‐resistant prostate cancer (mCRPC) is a lethal form of treatment‐resistant prostate cancer and poses significant therapeutic challenges.
Ahmad, Imran, Blomme, Arnaud, Edwards, Joanne, Fleming, Janis, Hamdy, Freddie C., Harle, Victoria, Hedley, Ann, Leung, Hing Y., Loveridge, Carolyn, Mackay, Gillian, Mui, Ernest, Patel, Rachana, Repiscak, Peter, Salji, Mark, Sansom, Owen J., Teo, Katy, van den Broek, Niels   +16 more
core   +2 more sources

Si Inhibited Osteoclastogenesis: The Role of Fe and the Fenton Reaction

Advanced Healthcare Materials, EarlyView.
Silicate (Si) inhibition of osteoclastogenesis, is mediated by Fe. Si chemical interactions with Fe inhibit the Fenton reaction and intercellular ROS availability. This reduction in ROS availability inhibits osteoclastogenesis. The addition of Fe, in Si‐inhibited osteoclast cultures, restores the Fenton reaction, and osteoclastogenesis.
Yutong Li, Adriana‐Monica Radu, Azadeh Rezaei, Joel Turner, Kaveh Shakib, Akiko Obata, Toshihiro Kasuga, Gavin Jell   +7 more
wiley   +1 more source

Adenovirus-mediated hepatic overexpression of scavenger receptor class B type I accelerates chylomicron metabolism in C57BL/6J mice

Journal of Lipid Research, 2005
The function of scavenger receptor class B type I (SR-BI) in mediating the selective uptake of HDL cholesteryl esters is well established. In SR-BI-deficient mice, we recently observed a delayed postprandial triglyceride (TG) response, suggesting an ...
Ruud Out, Menno Hoekstra, Saskia C.A. de Jager, Paula de Vos, Deneys R. van der Westhuyzen, Nancy R. Webb, Miranda Van Eck, Eric A.L. Biessen, Theo J.C. Van Berkel   +8 more
doaj  

Fibrates Down-regulate Hepatic Scavenger Receptor Class B Type I Protein Expression in Mice*

Journal of Biological Chemistry, 2003
Fibrates are normolipidemic drugs used in atherogenic dyslipidemia because of their ability to raise high density lipoprotein (HDL) and decrease triglyceride levels.
P. Mardones, A. Pilon, M. Bouly, D. Durán, T. Nishimoto, H. Arai, K. Kozarsky, M. Altayó, J. Miquel, G. Luc, V. Clavey, B. Staels, A. Rigotti   +12 more
semanticscholar   +1 more source

Expression of the Scavenger Receptor Class B type I (SR-BI) family in Drosophila melanogaster

The International Journal of Developmental Biology, 2011
In mammals, cholesterol is transformed into steroid hormones in the adrenal gland, the ovaries or the testes. The Scavenger Receptors Class B Type I (SR-BI) are membrane proteins that belong to the CD36 family and participate in the selective uptake of high density lipoprotein cholesteryl ester in the mammalian steroidogenic tissues.
Coralia Pérez, Leire Herboso, Ana Talamillo, Rosa Barrio   +3 more
openaire   +4 more sources

Identification of a Candidate CD5 Homologue in the Amphibian Xenopus laevis [PDF]

, 1995
We identified a novel T cell Ag in the South African clawed toad (Xenopus laevis) by a mAb designated 2B1. This Ag is present in relatively high levels on most thymocytes, approximately 65% of splenocytes, 55% of PBL, and 65% of intestinal lymphocytes ...
Cooper, Max D., Gartland, Lanier A., Göbel, Thomas W. F., Horton, John D., Jürgens, Jutta B., Pasquier, Louis D.   +5 more
core  

Activated Bone Marrow-Derived Macrophages Eradicate Alzheimer's-Related Aβ42 Oligomers and Protect Synapses. [PDF]

, 2020
Impaired synaptic integrity and function due to accumulation of amyloid β-protein (Aβ42) oligomers is thought to be a major contributor to cognitive decline in Alzheimer's disease (AD). However, the exact role of Aβ42 oligomers in synaptotoxicity and the
Black, Keith L, Daley, David A, Fuchs, Dieu-Trang, Garcia, Veronica J, Hayden, Eric Y, Koronyo, Yosef, Koronyo-Hamaoui, Maya, Li, Songlin, Rentsendorj, Altan, Rutishauser, Ueli, Sheyn, Julia, Teplow, David B, Torbati, Tania   +12 more
core  

A Consensus Definitive Classification of Scavenger Receptors and Their Roles in Health and Disease [PDF]

, 2017
Scavenger receptors constitute a large family of proteins that are structurally diverse and participate in a wide range of biological functions. These receptors are expressed predominantly by myeloid cells and recognize a diverse variety of ligands ...
Acton, Acton, Aziz-Seible, Bartolome, Benita McVicker, Bridge, Casey, Chen, Cong, Cynthia L. Baldwin, Dachy, Dawn M. E. Bowdish, Debanne, Dzwonek, Endemann, Fogelman, Geoffrey M. Thiele, Guy, Janice C. Telfer, Joachim Herz, John Loike, Joseph El Khoury, Krieger, Kurt Drickamer, Lester Kobzik, Maria Febbraio, McVicker, McVicker, McVicker, Mercy R. PrabhuDas, Monty Krieger, Murphy, Newton, Paul L. Bollyky, Pike, Robert C. Speth, Ruppert, Samuel D. Wright, Samuel Silverstein, Soren K. Moestrup, Steven R. Post, Stockert, Tatsuya Sawamura, Terry K. Means, van der Laan, Wilkinson, Xiang-Yang Wang   +46 more
core   +1 more source

Covalent Organic Frameworks for Photocatalysis

Advanced Materials, EarlyView.
This review provides an overview of recent advances in covalent organic frameworks (COFs) for photocatalysis, focusing on sustainable energy applications like water splitting, hydrogen peroxide generation, and CO2 and N2 reduction. It discusses design principles, structure‐function relationships, challenges in COF photocatalysis, and strategies to ...
Bikash Mishra, Akhtar Alam, Avanti Chakraborty, Bidhan Kumbhakar, Samrat Ghosh, Pradip Pachfule, Arne Thomas   +6 more
wiley   +1 more source

Apolipoprotein A1 Modulates Teff/Treg Balance Through Scavenger Receptor Class B Type I-Dependent Mechanisms in Experimental Autoimmune Uveitis. [PDF]

Invest Ophthalmol Vis Sci, 2022
Huang H, Li Z, Huang J, Xie Y, Xiao Z, Hu Y, Chen G, Wang M, Li Z, Chen Q, Zhu W, Su W, Luo Y, Chen X, Liang D.   +14 more
europepmc   +1 more source