Results 111 to 120 of about 55,191 (290)

Topology of Scavenger Receptor Class B Type I (SR-BI) on Brush Border Membrane

Journal of Veterinary Science, 2002
Both hydropathy plot and in vitro translation results predict the topology of SR-BI; the receptor is an integral membrane protein of 509 amino acids, consisting of a short cytoplasmic N-terminus of 9 amino acids followed by a first transmembrane domain of 22 amino acids, the extracellular domain of 408 amino acids, the second transmembrane domain of 22
Chang-Hoon, Han, Mun-Han, Lee
openaire   +2 more sources

Turning Unpredictable Biomolecule Adsorption to Controlled Corona Formation: Focus on Carbon Nanomaterials

Advanced Materials, EarlyView.
Controlling the protein corona formation onto carbon nanomaterials (CNMs) enhances their functionalities as platforms for cancer theranostics. Here, we reviewed the effects of the intrinsic and acquired properties of CNMs on protein corona formation, the consequent biological and toxicological outcomes, and the strategies to reshape corona formation ...
Yajuan Zou, Yalei Hu, Jie Yu, Naoki Komatsu, Yuta Nishina, Alberto Bianco   +5 more
wiley   +1 more source

Drug treatment of hypertension: focus on vascular health [PDF]

, 2016
Hypertension, the most common preventable risk factor for cardiovascular disease and death, is a growing health burden. Serious cardiovascular complications result from target organ damage including cerebrovascular disease, heart failure, ischaemic heart
Cameron, Alan C., Lang, Ninian N., Touyz, Rhian M.   +2 more
core   +1 more source

AI–Guided 4D Printing of Carnivorous Plants–Inspired Microneedles for Accelerated Wound Healing

Advanced Materials, EarlyView.
This work presents an artificial intelligence (AI)‐guided 4D‐printed microneedle platform inspired by carnivorous plants for wound healing. A thermo‐responsive shape memory polymer enables body temperature–triggered self‐coiling for autonomous wound closure.
Hyun Lee, Moon‐Jo Kim, DongEung Kim, Chan Ho Moon, Seojoon Bang, Hyeong Seok Kang, Ju Yeong Gwon, Jong Hwa Seo, Junhyub Jeon, Junhyuk Son, Munwon Lim, Minho Kang, Dong Yun Lee, Donghyun Lim, Jung‐Hoon Park, Gi Doo Cha, Soo‐Hong Lee, Tae‐Sik Jang, Kisuk Yang, Yunho Jeong, Youngho Eom, Hyun‐Do Jung   +21 more
wiley   +1 more source

Scavenger receptor class B type I-mediated uptake of serum cholesterol is essential for optimal adrenal glucocorticoid production

Journal of Lipid Research, 2009
Impaired scavenger receptor class B type I (SR-BI)-mediated uptake of HDL-cholesterol esters (HDL-CE) induces adrenal insufficiency in mice. Humans contain an alternative route of HDL-CE clearance, namely through the transfer by cholesteryl ester ...
Menno Hoekstra, Dan Ye, Reeni B. Hildebrand, Ying Zhao, Bart Lammers, Miranda Stitzinger, Johan Kuiper, Theo J.C. Van Berkel, Miranda Van Eck   +8 more
doaj   +1 more source

Polymersome-Mediated Delivery of Combination Anticancer Therapy to Head and Neck Cancer Cells: 2D and 3D in Vitro Evaluation [PDF]

, 2014
Polymersomes have the potential to encapsulate and deliver chemotherapeutic drugs into tumor cells, reducing off-target toxicity that often compromises anticancer treatment.
Acton S. L., Ahmed F., Allen-Hoffmann B. L., Araki T., Barenholz Y., Blanazs A., Canton I., Chen W., Christian D. A., Colley H. E., Craig Murdoch, Crosasso P., Denis Cecchin, Discher D. E., Duncan R., Eckert A. W., Giuseppe Battaglia, Haisma H. J., Hastie C., Hearnden V., Helen E. Colley, Hirschhaeuser F., Hu C. M., Husemann J., Irene Canton, Jane A. McKeating, Jeppe Madsen, Kamphuis M. M., Ke Hu, Koudelka S., Lee J. S., Li S., Lomas H., Lomas H., LoPresti C., Martin H. Thornhill, Massignani M., Massignani M., Massignani M., Matsumura Y., Mehta G., Milagros Avila-Olias, Moghimi S. M., Mooberry L. K., Mross K., Murdoch C., Nicholas Warren, O’Neil C. P., Patel P. C., Pegoraro C., Price K. A., Saha K., Sankar V., Schroeder A., Sheila MacNeil, Silverstein R. L., Singla A. K., Smith L. E., Steven P. Armes, Valacchi G., Vanessa Hearnden, Volkova M., von Gruenigen V., Wang L., Webb N. R., Weiszhar Z.   +65 more
core   +1 more source

Inert Catalytic Sites Unlocked by Micropollutants for Rapid Water Decontamination with Near‐Complete Chemical Utilization

Advanced Materials, EarlyView.
Micropollutants can act as molecular triggers that activate a newly designed and chemically inert Fenton‐like PKU‐24 catalyst for on‐demand singlet oxygen generation from peroxymonosulfate (PMS), enabling nearly complete peroxide utilization and selective micropollutant removal from complex real‐world wastewater.
Yu‐Hang Li, Mingyi Liu, Yuanhao Li, Yaran Bai, Fu‐Xue Wang, Xiaoyi Hu, Xiaoguang Duan, Haodong Ji   +7 more
wiley   +1 more source

Hepatic cholesterol and bile acid metabolism and intestinal cholesterol absorption in scavenger receptor class B type I-deficient mice

Journal of Lipid Research, 2001
The scavenger receptor class B type I (SR-BI), which is expressed in the liver and intestine, plays a critical role in cholesterol metabolism in rodents.
Pablo Mardones, Verónica Quiñones, Ludwig Amigo, Mauricio Moreno, Juan Francisco Miquel, Margrit Schwarz, Helena E. Miettinen, Bernardo Trigatti, Monty Krieger, Sonya VanPatten, David E. Cohen, Attilio Rigotti   +11 more
doaj   +1 more source

Innate immunity and neuroinflammation [PDF]

, 2013
Copyright © 2013 Abhishek Shastri et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly ...
Bonifati, DM, Kishore, U, Shastri, A
core   +3 more sources

Radiotherapy Enhancement by Gold Nanocluster‐functionalized Nanoliposomes Using Polychromatic Orthovoltage X‐ray Irradiation

Advanced Materials Interfaces, EarlyView.
Lipid drug carriers to which ultra‐small gold nanoparticles were added enabled more efficient radiotherapy of cultured pancreatic cancer tumors. These nanoparticles boosted radiation‐induced damage to tumors by generating more reactive molecules, though higher gold levels are needed for strong benefits.
Nazareth Milagros Carigga Gutierrez, Eaazhisai Kandiah, Sofia Leo, Erwan Dupont, Fabrizio Johnson‐Corrales, Marc‐André Hograindleur, Sarvenaz Keshmiri, Hélène Elleaume, Benoit Busser, Romain Haudecoeur, Véronique Jacob, Anthony Vella, Véronique Josserand, Maxime Henry, Jean‐Luc Coll, Amandine Hurbin, Xavier Le Guével, Mans Broekgaarden   +17 more
wiley   +1 more source