Human scavenger receptor class B type I variants, lipid traits, and cardiovascular disease. [PDF]
Over the years, pioneering work from Monty Krieger’s laboratory has solidified the role of scavenger receptor class B type I (SR-BI) as a physiologically relevant lipoprotein receptor, especially in mouse models.1,2 It is safe to conclude that the complete absence of SR-BI in mice is associated with significant increases in circulating high-density ...
Vickers KC, Rodriguez A.
europepmc +5 more sources
Liver receptor homolog 1 controls the expression of the scavenger receptor class B type I [PDF]
The scavenger receptor class B type I (SR‐BI), which mediates selective cellular cholesterol uptake from high‐density lipoproteins (HDLs), plays a key role in reverse cholesterol transport. The orphan nuclear receptor liver receptor homolog 1 (LRH‐1) and SR‐BI are co‐expressed in liver and ovary, suggesting that LRH‐1 might control the expression of SR‐
K. Schoonjans+7 more
semanticscholar +4 more sources
The class B type I scavenger receptor, (SR-BI), is a member of the CD36 superfamily of proteins and is a physiologically relevant, high affinity cell surface high density lipoprotein (HDL) receptor that mediates selective lipid uptake.
Xiangju Gu+5 more
openalex +2 more sources
Binding of High Density Lipoprotein (HDL) and Discoidal Reconstituted HDL to the HDL Receptor Scavenger Receptor Class B Type I [PDF]
The binding of apoA-I-containing ligands to the HDL receptor scavenger receptor class B type I (SR-BI) was characterized using two different assays. The first employed conventional binding or competition assays with125I-labeled ligands.
Kalliopi Liadaki+8 more
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Role Analysis of the scarb1 Gene in the Pigmentation of Neocaridina denticulata sinensis [PDF]
Body color is a key economic trait for Neocaridina denticulata sinensis, an important ornamental shrimp. Scarb1 may be an important mediator of astaxanthin uptake, changing the shrimp’s body color.
Lili Zhang+3 more
doaj +2 more sources
Scavenger receptor class B, type I-mediated uptake of A1AT by pulmonary endothelial cells.
In addition to exerting a potent anti-elastase function, α-1 antitrypsin (A1AT) maintains the structural integrity of the lung by inhibiting endothelial inflammation and apoptosis. A main serpin secreted in circulation by hepatocytes, A1AT requires uptake by the endothelium to achieve vasculoprotective effects.
Lockett AD+9 more
europepmc +5 more sources
The scavenger receptor class B type I (SR-BI) mediates the selective uptake of cholesteryl esters from high-density lipoprotein (HDL) and cholesterol secretion into bile in the liver.
Mamoru Ikemoto+9 more
openalex +2 more sources
MicroRNAs 125a and 455 repress lipoprotein-supported steroidogenesis by targeting scavenger receptor class B type I in steroidogenic cells. [PDF]
Hu Z, Shen WJ, Kraemer FB, Azhar S.
europepmc +2 more sources
Effects of Extracts from Tiaozhi Granule and Its Components on Expression of Scavenger Receptor Class B Type I. [PDF]
Yu X+5 more
europepmc +3 more sources
Different requirements for scavenger receptor class B type I in hepatitis C virus cell-free versus cell-to-cell transmission. [PDF]
Catanese MT+5 more
europepmc +2 more sources