Results 71 to 80 of about 103,100 (354)

Scavenger Receptor Class B Type I as a Mediator of Cellular Cholesterol Efflux to Lipoproteins and Phospholipid Acceptors*

Journal of Biological Chemistry, 1998
We recently reported that the rate of efflux of cholesterol from cells to high density lipoprotein (HDL) was related to the expression level of scavenger receptor class B type I (SR-BI).
Bo Jian, M. de la Llera-Moya, Yong Ji, Nan Wang, M. Phillips, J. Swaney, A. Tall, G. Rothblat   +7 more
semanticscholar   +1 more source

Scavenger receptor class B, type I (SR-BI) is the major route for the delivery of high density lipoprotein cholesterol to the steroidogenic pathway in cultured mouse adrenocortical cells.

Proceedings of the National Academy of Sciences of the United States of America, 1997
The class B, type I scavenger receptor, SR-BI, binds high density lipoprotein (HDL) and mediates the selective uptake of HDL cholesteryl ester (CE) by cultured transfected cells.
R. Temel, B. Trigatti, R. DeMattos, S. Azhar, M. Krieger, David L. Williams   +5 more
semanticscholar   +1 more source

Neutralizing Antibody-Resistant Hepatitis C Virus Cell-to-Cell Transmission [PDF]

, 2010
Hepatitis C virus (HCV) can initiate infection by cell-free particle and cell-cell contact-dependent transmission. In this study we use a novel infectious coculture system to examine these alternative modes of infection.
Balfe, Peter, Baumert, Thomas, Brimacombe, Claire L, Flores, Maria Victoria, Grove, Joe, Hu, Ke, Krieger, Sophie E, McKeating, Jane A, Meredith, Luke W, Syder, Andrew J, Tellinghuisen, Timothy L, Timpe, Jennifer M, Wong-Staal, Flossie   +12 more
core   +4 more sources

Expression and regulation of scavenger receptor class B type I (SR-BI) in gall bladder epithelium [PDF]

Gut, 2003
Biliary lipid absorption by the gall bladder mucosa and the cholesterol content of the gall bladder wall appear to play a role in cholesterol gall stone formation. As the scavenger receptor class B type I (SR- BI) regulates cellular cholesterol uptake, we studied its expression in human and murine gall bladders, its regulation by increased biliary ...
Miquel, JF, Moreno, M, Amigo, L, Molina, H, Mardones, P, Wistuba, II, Rigotti, A   +6 more
openaire   +6 more sources

The microglial "activation" continuum: from innate to adaptive responses [PDF]

, 2005
Microglia are innate immune cells of myeloid origin that take up residence in the central nervous system (CNS) during embryogenesis. While classically regarded as macrophage-like cells, it is becoming increasingly clear that reactive microglia play more ...
Nikolic, Veljko, Tan, Jun, Town, Terrence   +2 more
core   +3 more sources

Interaction vesicles as emerging mediators of host‐pathogen molecular crosstalk and their implications for infection dynamics

FEBS Letters, EarlyView.
Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke, Izadora Volpato Rossi, Marcel I. Ramirez   +2 more
wiley   +1 more source

Scavenger Receptor Class B Type I-mediated Reverse Cholesterol Transport Is Inhibited by Advanced Glycation End Products*

Journal of Biological Chemistry, 2001
Cellular interactions of advanced glycation end products (AGE) are mediated by AGE receptors. We demonstrated previously that class A scavenger receptor types I and II (SR-A) and CD36, a member of class B scavenger receptor family, serve as the AGE ...
N. Ohgami, R. Nagai, A. Miyazaki, M. Ikemoto, H. Arai, S. Horiuchi, H. Nakayama   +6 more
semanticscholar   +1 more source

ROLE OF SCAVENGER RECEPTOR CLASS B TYPE I IN THYMOPOIESIS [PDF]

, 2014
T cells, which constitute an essential arm in the adaptive immunity, complete their development in the thymus through a process called thymopoiesis. However, thymic involution can be induced by a couple of factors, which impairs T cell functions and is ...
Zheng, Zhong
core   +1 more source

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

Molecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez, Pablo Juanes‐Velasco, Marina L. García‐Vaquero, Conrad Droste, Alicia Landeira‐Viñuela, Miguel Alcoceba, Helena Fidalgo‐Gómez, Sara Misiego‐Herrero, Almudena Navarro‐Bailón, Mónica Baile, José M. Bastida, Jose Manuel Sanchez‐Santos, Rafael Góngora, Julia Almeida, Marcos Gonzalez‐Diaz, Alberto Orfao, Javier De Las Rivas, Manuel Fuentes   +17 more
wiley   +1 more source

Three polymethoxyflavones from the peel of Citrus reticulata “Chachi” inhibits oxidized low-density lipoprotein-induced macrophage-derived foam cell formation

Frontiers in Cardiovascular Medicine, 2022
Foam cell formation is the hallmark of the development and progression of atherosclerosis. The aim of this study was to investigate the regulatory effects of three polymethoxyflavones (PMFs), namely, tangeretin (TAN), 5,6,7,3′,4′,5′-hexamethoxyflavone ...
Pu-Lin Liang, Qian-Wen Liang, Pei-Wen He, Xue-Lian Chen, Ya Xu, Hai-Sheng Tu, Liang Zhang, Xiao-Hui Qiu, Xiao-Hui Qiu, Jing Zhang, Zhi-Hai Huang, Wen Xu, Wen Xu   +12 more
doaj   +1 more source