Results 81 to 90 of about 56,399 (161)

Apolipoprotein E and Atherosclerosis: From Lipoprotein Metabolism to MicroRNA Control of Inflammation. [PDF]

, 2018
Apolipoprotein (apo) E stands out among plasma apolipoproteins through its unprecedented ability to protect against atherosclerosis. Although best recognized for its ability to mediate plasma lipoprotein clearance in the liver and protect against ...
Hasty, Hui, Hussain, Lin, Mahley, Pepe, Roselaar   +6 more
core   +2 more sources

Cellular SR-BI and ABCA1-mediated cholesterol efflux are gender-specific in healthy subjectss⃞

Journal of Lipid Research, 2008
We evaluated the impact of gender differences in both the quantitative and qualitative features of HDL subspecies on cellular free cholesterol efflux through the scavenger receptor class B type I (SR-BI), ABCA1, and ABCG1 pathways.
Giovanna Catalano, Emilie Duchene, Zélie Julia, Wilfried Le Goff, Eric Bruckert, M. John Chapman, Maryse Guerin   +6 more
doaj   +1 more source

Novel Functions of Endothelial Scavenger Receptor Class B Type I. [PDF]

Curr Atheroscler Rep, 2021
Yu L, Dai Y, Mineo C.
europepmc   +1 more source

Apolipoprotein A1 Modulates Teff/Treg Balance Through Scavenger Receptor Class B Type I-Dependent Mechanisms in Experimental Autoimmune Uveitis. [PDF]

Invest Ophthalmol Vis Sci, 2022
Huang H, Li Z, Huang J, Xie Y, Xiao Z, Hu Y, Chen G, Wang M, Li Z, Chen Q, Zhu W, Su W, Luo Y, Chen X, Liang D.   +14 more
europepmc   +1 more source

Polymersome-Mediated Delivery of Combination Anticancer Therapy to Head and Neck Cancer Cells: 2D and 3D in Vitro Evaluation [PDF]

, 2014
Polymersomes have the potential to encapsulate and deliver chemotherapeutic drugs into tumor cells, reducing off-target toxicity that often compromises anticancer treatment.
Acton S. L., Ahmed F., Allen-Hoffmann B. L., Araki T., Barenholz Y., Blanazs A., Canton I., Chen W., Christian D. A., Colley H. E., Craig Murdoch, Crosasso P., Denis Cecchin, Discher D. E., Duncan R., Eckert A. W., Giuseppe Battaglia, Haisma H. J., Hastie C., Hearnden V., Helen E. Colley, Hirschhaeuser F., Hu C. M., Husemann J., Irene Canton, Jane A. McKeating, Jeppe Madsen, Kamphuis M. M., Ke Hu, Koudelka S., Lee J. S., Li S., Lomas H., Lomas H., LoPresti C., Martin H. Thornhill, Massignani M., Massignani M., Massignani M., Matsumura Y., Mehta G., Milagros Avila-Olias, Moghimi S. M., Mooberry L. K., Mross K., Murdoch C., Nicholas Warren, O’Neil C. P., Patel P. C., Pegoraro C., Price K. A., Saha K., Sankar V., Schroeder A., Sheila MacNeil, Silverstein R. L., Singla A. K., Smith L. E., Steven P. Armes, Valacchi G., Vanessa Hearnden, Volkova M., von Gruenigen V., Wang L., Webb N. R., Weiszhar Z.   +65 more
core   +1 more source

Functional LCAT deficiency in human apolipoprotein A-I transgenic, SR-BI knockout mice

Journal of Lipid Research, 2007
Reduction of plasma LCAT activity has been observed in several conditions in which the size of HDL particles is increased; however, the mechanism of this reduction remains elusive. We investigated the plasma activity, mass, and in vivo catabolism of LCAT
Lee Ji-Young, Robert M. Badeau, Mulya Anny, Boudyguina Elena, Abraham K. Gebre, Thomas L. Smith, John S. Parks   +6 more
doaj   +1 more source

Macrophage SR-BI mediates efferocytosis via Src/PI3K/Rac1 signaling and reduces atherosclerotic lesion necrosis[S]

Journal of Lipid Research, 2015
Macrophage apoptosis and efferocytosis are key determinants of atherosclerotic plaque inflammation and necrosis. Bone marrow transplantation studies in ApoE- and LDLR-deficient mice revealed that hematopoietic scavenger receptor class B type I (SR-BI ...
Huan Tao, Patricia G. Yancey, Vladimir R. Babaev, John L. Blakemore, Youmin Zhang, Lei Ding, Sergio Fazio, MacRae F. Linton   +7 more
doaj   +1 more source

Hepatic paraoxonase 1 ameliorates dysfunctional high-density lipoprotein and atherosclerosis in scavenger receptor class B type I deficient mice. [PDF]

Ann Transl Med, 2021
Zhao XJ, Liu LC, Guo C, Shen WW, Cao J, Du F, Wu DF, Yu H.   +7 more
europepmc   +1 more source

Secretory phospholipase A2 increases SR-BI-mediated selective uptake from HDL but not biliary cholesterol secretions⃞

Journal of Lipid Research, 2008
High density lipoprotein cholesterol represents a major source of biliary cholesterol. Secretory phospholipase A2 (sPLA2) is an acute phase enzyme mediating decreased plasma HDL cholesterol levels. Clinical studies reported a link between increased sPLA2
Uwe J.F. Tietge, Niels Nijstad, Rick Havinga, Julius F.W. Baller, Fjodor H. van der Sluijs, Vincent W. Bloks, Thomas Gautier, Folkert Kuipers   +7 more
doaj   +1 more source

Potential immunosuppressive effects of Escherichia coli O157:H7 experimental infection on the bovine host [PDF]

, 2016
Background: Enterohaemorrhagic Escherichia coli (EHEC), like E. coli O157:H7 are frequently detected in bovine faecal samples at slaughter. Cattle do not show clinical symptoms upon infection, but for humans the consequences after consuming contaminated ...
Cox, Eric, Kieckens, Evelien, Li, RW, Rybarczyk, Joanna, Vanrompay, Daisy   +4 more
core   +1 more source