Results 91 to 100 of about 53,683 (320)

A guide to bioinformatics for immunologists

Frontiers in Immunology, 2013
Bioinformatics includes a suite of methods, which are cheap, approachable, and many of which are easily accessible without any sort of specialized bioinformatic training. Yet, despite this, bioinformatic tools are under-utilized by immunologists. Herein,
Fiona Jane Whelan, Nicholas eYap, Michael G Surette, G. Brian eGolding, Dawn M. E. Bowdish   +4 more
doaj   +1 more source

Off‐The‐Shelf Multivalent Nanoconjugate Cancer Vaccine Rescues Host Immune Response against Melanoma

Advanced Materials, EarlyView.
A star‐shaped cross‐linked polyglutamate (StCl) nanocarrier delivers melanoma‐associated peptide antigens via redox‐responsive linkers, inducing lymph node‐targeted antigen presentation. The nanoconjugate activates dendritic cells, promotes effector T‐cell responses, and enables tumor regression even in humanized patient‐derived preclinical models ...
Liane IF Moura, Alessio Malfanti, Ana I Matos, Carina Peres, Ana Armiñán, Aroa Duro‐Castaño, Inmaculada Conejos‐Sánchez, María Medel, Snežana Đorđević, Paula Carrascosa, Bárbara Carreira, Rita C Acúrcio, Helena Xavier‐Ferreira, Alberto Hernández‐Barranco, Elena Castellano, Esther Roselló, José C. Machado, Héctor Peinado, María J. Vicent, Helena F. Florindo   +19 more
wiley   +1 more source

Hole Scavenging and Photo-Stimulated Recombination of Electron-Hole Pairs in Aqueous TiO2 Nanoparticles [PDF]

arXiv, 2004
It is shown that 532 nm and 1064 nm laser photoexcitation of trapped electrons generated by 355 nm photolysis of aqueous titania (TiO2) nanoparticles causes rapid photobleaching of their absorbance band in the visible and near IR. This photobleaching occurs within the duration of the laser pulse (3 ns FWHM); it is caused by photoinduced electron ...
arxiv  

HSL-knockout mouse testis exhibits class B scavenger receptor upregulation and disrupted lipid raft microdomains[S]

Journal of Lipid Research, 2012
There is a tight relationship between fertility and changes in cholesterol metabolism during spermatogenesis. In the testis, class B scavenger receptors (SR-B) SR-BI, SR-BII, and LIMP II mediate the selective uptake of cholesterol esters from HDL, which ...
María Emilia Casado, Lydia Huerta, Ana Isabel Ortiz, Mirian Pérez-Crespo, Alfonso Gutiérrez-Adán, Fredric B. Kraemer, Miguel Ángel Lasunción, Rebeca Busto, Antonia Martín-Hidalgo   +8 more
doaj  

Mechanical and Light Activation of Materials for Chemical Production

Advanced Materials, EarlyView.
The actuation of stomata—referring to their opening and closing—is crucial for photosynthesis because it regulates gas exchange and water balance. Here, it is investigated if this life‐like property could enhance the photocatalytic properties of soft materials.
Luka Đorđević, Tyler J. Jaynes, Hiroaki Sai, Marianna Barbieri, Jacob E. Kupferberg, Nicholas A. Sather, Steven Weigand, Samuel I. Stupp   +7 more
wiley   +1 more source

Free Radical Scavenging and Cytotoxic Activities of Substituted Pyrimidines [PDF]

arXiv, 2020
A library of substituted pyrimidines was synthesized and evaluated for free radical scavenging, and in vitro cytotoxic activity in 3T3 cells. All compounds showed good free radical scavenging activity with IC50 values in the range of 42.9 + 0.31 to 438.3 3.3 {\mu}M as compared to the standard butylated hydroxytoluene having IC50 value of 128.83 2.
arxiv  

Scavenger Receptor A: A New Route for Adenovirus 5

Molecular Pharmaceutics, 2009
Adenoviruses are common pathogens associated with respiratory diseases, gastrointestinal illnesses and/or conjunctivitis. Currently, this virus is used as a vector in gene therapy trials. The promise of viral gene therapy applications is substantially reduced because the virus is cleared by liver macrophages upon systemic administration.
Haisma, H, Boesjes, M, Beerens, A, van der Strate, B, Curiel, D, Plüddemann, A, Gordon, S, Bellu, A   +7 more
openaire   +3 more sources

Photo‐Induced Bandgap Engineering of Metal Halide Perovskite Quantum Dots In Flow

Advanced Materials, EarlyView.
This work presents a photochemical synthetic route for bandgap engineering of metal halide perovskite quantum dots. Utilizing a material‐efficient microfluidic platform, the underlying mechanism of the photo‐induced anion exchange reaction (PIAER) of metal halide perovskite quantum dots is unveiled and first instance of the PIAER‐enabled synthesis of ...
Pragyan Jha, Nikolai Mukhin, Arup Ghorai, Hamed Morshedian, Richard B. Canty, Fernando Delgado‐Licona, Emily E. Brown, Austin J. Pyrch, Felix N. Castellano, Milad Abolhasani   +9 more
wiley   +1 more source

Multiple Routes for Glutamate Receptor Trafficking: Surface Diffusion and Membrane Traffic Cooperate to Bring Receptors to Synapses [PDF]

Science's STKE (electronic resource) : signal transduction knowledge environment 327 (21/03/2006) 13, 2007
Trafficking of glutamate receptors into and out of synapses is critically involved in the plasticity of excitatory synaptic transmission. Endocytosis and exocytosis of receptors have initially been thought to account alone for this trafficking. However, membrane proteins also traffic through surface lateral diffusion in the plasma membrane. We describe
arxiv  

The Antimicrobial Peptide Cathelicidin Exerts Immunomodulatory Effects via Scavenger Receptors. [PDF]

Int J Mol Sci, 2023
Amagai R, Takahashi T, Terui H, Fujimura T, Yamasaki K, Aiba S, Asano Y.   +6 more
europepmc   +1 more source