Results 211 to 220 of about 53,683 (320)

Functional Materials Targeted Regulation of Gasdermins: From Fundamentals to Functionalities and Applications

Advanced Science, EarlyView.
Targeted regulation of pyroptosis to modulate the immune landscape is a novel design strategy for cancer immunotherapy and anti‐inflammatory treatment. Pyroptosis, as a double‐edged sword, underscores the importance of optimizing the design strategy of functional materials and appropriately activating pyroptosis for the effective treatment of diseases.
Luyao Tian, Shuo Piao, Xia Li, Lanping Guo, Luqi Huang, Wenyuan Gao   +5 more
wiley   +1 more source

Scavenger Receptor BI Mediates the Selective Uptake of Oxidized Cholesterol Esters by Rat Liver [PDF]

, 1999
Kees Fluiter, Wolgang Sattler, Maria C. de Beer, Patrice M. Connell, Deneys R. van der Westhuyzen, Theo J.C. van Berkel   +5 more
openalex   +1 more source

Robust Controlled Degradation of Enzyme Loaded PCL‐Based Fibrous Scaffolds Toward Scarless Skin Tissue Regeneration

Advanced Science, EarlyView.
A novel biodegradable wound dressing (E‐PCLs) based on polycaprolactone (PCL) and an enzyme complex (RHP‐BCL) is developed using a fiber microfluidic electrospinning technique. The dressing achieves complete degradation within 14 days, eliminates microplastic residues, and promotes scar‐free healing (99% in 21 days).
Lingling Fan, Weiliang Dong, Jianqi Lu, Yujia Peng, Bin Xie, Ping Wei, Min Jiang, Su Chen   +7 more
wiley   +1 more source

Mechanical Biomimetic Nanocomposites for Multidimensional Treatment of Arterial Thrombosis

Advanced Science, EarlyView.
In this study, a mechanical biomimetic nanocomposite is developed, guided by photoacoustic imaging, to achieve highly efficient and safe thrombolysis through the synergistic effects of photothermal therapy and pharmacological intervention. Most notably, the nanoparticle improves the microenvironment of arterial thrombi, marked by high shear stress and ...
Ying Li, Qi Xiang, Yan Zhang, Fuxue Luo, Yunfang Wu, Haitao Ran, Yang Cao   +6 more
wiley   +1 more source

Exploiting the Unique Properties of Lanthanide Complexes as FRET Probes: from Quantitation to Protein Dynamics

Analysis &Sensing, Volume 3, Issue 1, January 2023., 2023
Lanthanide complexes are ideal donors for FRET (Förster resonance energy transfer) assays with a variety of applications from easy‐to‐use quantitation of proteins to sophisticated experiments giving real‐time information on the movement of proteins. This Review article introduces the principles of using such assays before surveying the full scope of ...
Simon Wheeler, Stephen J. Butler
wiley   +1 more source

<title>Effect of photodynamic therapy in intimal hyperplasia by phthalocyanine conjugated to the scavenger-receptor ligand, maleylated bovine serum albumin</title> [PDF]

, 1997
Shigeki Ito, Tsuneyuki Nagae, Shin Ishimaru, Sara Chau, Triet Dang, Leslie Anne Sabiniano, Mizuho Zempo, Mark C. Booth, Lih‐Huei L. Liaw, Tatiana B. Krasieva, Bruce J. Tromberg, Johan E. van Lier, Michael W. Berns, Samuel E. Wilson   +13 more
openalex   +1 more source

Endogenous Near‐Infrared Chemiluminescence: Imaging‐Guided Non‐Invasive Thrombolysis and Anti‐Inflammation Based on a Heteronuclear Transition Metal Complex

Advanced Science, EarlyView.
Cu2Ir NPs based on a Cu‐porphyrin core and cyclometalated Ir(III) substituents achieve combined endogenous peroxynitrite‐triggered NIR chemiluminescence imaging, PTT and PDT for successfully achieving safe thrombolysis, antioxidant and anti‐inflammatory multifunctionality in one single molecule.
Ziwei Wang, Bo Zhu, Wenxin Nie, Liping Zhang, Nan Xiao, Qiaohua Zhang, Zihan Wu, Chunguang Shi, Weijin Zhu, Qianwen Liu, Dongxia Zhu, Martin R. Bryce, Lijie Ren, Ben Zhong Tang   +13 more
wiley   +1 more source

The Multiple Roles of Macrophage Scavenger Receptors (MSR) in vivo : Resistance to Atherosclerosis and Susceptibility to Infection in MSR Knockout Mice

, 1997
Hiroshi Suzuki, Yukiko Kurihara, Motohiro Takeya, Nobuo Kamada, Motoyuki Kataoka, Kou‐ichi Jishage, Hisashi Sakaguchi, J. Kar Kruijt, Takayuki Higashi, Tsukasa Suzuki, Theo J.C. van Berkel, Seikoh Horiuchi, Kiyoshi Takahashi, Y Yazaki, Tatsuhiko Kodama   +14 more
openalex   +2 more sources

Macrophage scavenger receptor CD36 is the major receptor for LDL modified by monocyte-generated reactive nitrogen species [PDF]

, 2000
Eugene A. Podrez, Maria Febbraio, Nader Sheibani, David Schmitt, Roy L. Silverstein, David P. Hajjar, Peter A. Cohen, William A. Frazier, Henry F. Hoff, Stanley L. Hazen   +9 more
openalex   +1 more source

Bacterial Capture‐Killing Capsules with Remodeling Bone Immune Microenvironment for the Effective Treatment of Osteomyelitis

Advanced Science, EarlyView.
The PC‐O@TOB capsules are designed to exhibit bactericidal effects, regulate the bone immune microenvironment by promoting M2 macrophage polarization, eliminate excessive ROS, and enhance bone regeneration, providing a novel multi‐dimensional approach for the treatment of osteomyelitis.
Dong Yang, Chang Shu, Chengwei Xu, Xingjie Zan, Shaoyin Wei, Chenglong Wang, Lianxin Li   +6 more
wiley   +1 more source