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Scavenger receptors: Implications in atherothrombotic disorders
International Journal of Biochemistry and Cell Biology, 2011 Scavenger receptors are modified lipoprotein binding receptors, expressed on the surface of a variety of cells including endothelial, macrophages and platelets.
Neha Gupta
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Scavenger Receptors are Present on Rabbit Aortic Endothelial Cells In Vivo
Arteriosclerosis, Thrombosis, and Vascular Biology, 1997 Endothelial cells metabolize modified LDL, but attempts to detect scavenger receptors in this cell type in vitro have been unsuccessful. To determine whether scavenger receptors are present on endothelial cells in vivo, species-specific reagents were ...
Debra Rateri +2 more
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Hemoglobin and Heme Scavenger Receptors
Antioxidants & Redox Signaling, 2010Heme, the functional group of hemoglobin, myoglobin, and other hemoproteins, is a highly toxic substance when it appears in the extracellular milieu. To circumvent potential harmful effects of heme from hemoproteins released during physiological or pathological cell damage (such as hemolysis and rhabdomyolysis), specific high capacity scavenging ...
Nielsen MJ, Møller HJ, Moestrup SK.
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Macrophage scavenger receptors
Current Opinion in Lipidology, 1994Macrophage scavenger receptors are integral membrane proteins whose ability to bind and degrade modified LDL has implicated them in the process of atherosclerotic foam cell formation. Their ability to bind non-lipoprotein ligands suggests that they participate in other macrophage-associated host defense activities.
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Graphene Nanoflake Uptake Mediated by Scavenger Receptors [PDF]
Nano Letters, 2019 The biological interactions of graphene have been extensively investigated over the last 10 years. However, very little is known about graphene interactions with the cell surface and how the graphene internalization process is driven and mediated by ...
Jennifer McIntyre +2 more
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Identification of the haemoglobin scavenger receptor
Nature, 2001Intravascular haemolysis is a physiological phenomenon as well as a severe pathological complication when accelerated in various autoimmune, infectious (such as malaria) and inherited (such as sickle cell disease) disorders. Haemoglobin released into plasma is captured by the acute phase protein haptoglobin, which is depleted from plasma during ...
Madsen, Mette; id_orcid 0000-0001-7241-6505 +6 more
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Macrophage scavenger receptors and atherosclerosis
Trends in Cardiovascular Medicine, 1992The fatty streak is the earliest visible atherosclerotic lesion. Microscopically, this lesion consists of a subendothelial collection of macrophage foam cells that are characterized by their content of numerous lipid droplets. Investigations into the mechanisms responsible for foam cell formation have led to the identification of macrophage scavenger ...
H, Wu, K S, Moulton, C K, Glass
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Scavenger receptor regulation and atherosclerosis
BioFactors, 2000AbstractAtherosclerosis and its complications, such as coronary heart disease, heart infarction and stroke, are the leading causes of death in the developed world. High blood pressure, diabetes, smoking and a diet high in cholesterol and lipids clearly increase the likelihood of premature atherosclerosis, albeit other factors, such as the individual ...
ZINGG JM, RICCIARELLI, ROBERTA, AZZI A.
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Collagenous macrophage scavenger receptors
Current Opinion in Lipidology, 1996Collagen, the most abundant protein in the human body, is a major constituent of extracellular matrix. Among macrophage membrane proteins, type I and II scavenger receptors and MARCO contain a collagenous domain. Analysis of type I and II receptor knockout mice and histochemical studies indicate that these proteins play roles in scavenger, adhesion and
T, Kodama +5 more
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Scavenger receptors in innate immunity
Current Opinion in Immunology, 1996Scavenger receptors are cell-surface proteins expressed by mammalian monocytes and macrophages and by invertebrate hemocytes, among other cell types. They exhibit distinctive ligand-binding properties, recognizing a wide range of ligands that include microbial surface constituents and intact microbes.
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