Results 211 to 220 of about 54,319 (245)

Identification of the haemoglobin scavenger receptor

Nature, 2001
Intravascular haemolysis is a physiological phenomenon as well as a severe pathological complication when accelerated in various autoimmune, infectious (such as malaria) and inherited (such as sickle cell disease) disorders. Haemoglobin released into plasma is captured by the acute phase protein haptoglobin, which is depleted from plasma during ...
Madsen, Mette; id_orcid 0000-0001-7241-6505, Graversen, J. H., Jacobsen, Christian, Sonne, Ole, Hoffmann, H.-J., Law, S. K. A., Moestrup, Søren Kragh   +6 more
openaire   +3 more sources

Scavenger receptor regulation and atherosclerosis

BioFactors, 2000
AbstractAtherosclerosis and its complications, such as coronary heart disease, heart infarction and stroke, are the leading causes of death in the developed world. High blood pressure, diabetes, smoking and a diet high in cholesterol and lipids clearly increase the likelihood of premature atherosclerosis, albeit other factors, such as the individual ...
ZINGG JM, RICCIARELLI, ROBERTA, AZZI A.
openaire   +4 more sources

Collagenous macrophage scavenger receptors

Current Opinion in Lipidology, 1996
Collagen, the most abundant protein in the human body, is a major constituent of extracellular matrix. Among macrophage membrane proteins, type I and II scavenger receptors and MARCO contain a collagenous domain. Analysis of type I and II receptor knockout mice and histochemical studies indicate that these proteins play roles in scavenger, adhesion and
T, Kodama, T, Doi, H, Suzuki, K, Takahashi, Y, Wada, S, Gordon   +5 more
openaire   +2 more sources

Scavenger receptors in innate immunity

Current Opinion in Immunology, 1996
Scavenger receptors are cell-surface proteins expressed by mammalian monocytes and macrophages and by invertebrate hemocytes, among other cell types. They exhibit distinctive ligand-binding properties, recognizing a wide range of ligands that include microbial surface constituents and intact microbes.
exaly   +3 more sources

Scavenger Receptors in the Pathogenesis of Viral Infections

Viral Immunology, 2022
Scavenger receptors (SR) are not only pattern recognition receptors involved in the immune response against pathogens but are also important receptors exploited by different virus to enter host cells, and thus represent targets for antiviral therapy. The high mutation rates of viruses, as well as their small genomes are partly responsible for the high ...
Nora A. Fierro, Evelyn Rivera-Toledo, Fernanda Ávila-Horta, Julio Y. Anaya-Covarrubias, Fela Mendlovic   +4 more
openaire   +2 more sources

Platelet hyperreactivity, scavenger receptors and atherothrombosis [PDF]

Journal of Thrombosis and Haemostasis, 2009
Scavenger receptors (SRs) were initially identified as macrophage receptors that recognize modified lipoproteins. The lists of SRs, their ligands and cells expressing SRs have been significantly extended during the last two decades. What has become clear is that many ligands of SRs are present in vivo only in pathologic conditions.
M, Valiyaveettil, E A, Podrez
exaly   +3 more sources

Scavenger receptor BI: A scavenger receptor with a mission to transport high density lipoprotein lipids

Current Opinion in Lipidology, 2004
This review will survey recent findings on the cholesterol transport and scavenger functions of scavenger receptor BI. Although scavenger receptor BI and CD36 bind many of the same ligands, these two receptors have very specific lipid transport functions: CD36 facilitates the uptake of long chain fatty acids and SR-BI mediates the transport of ...
Margery A, Connelly, David L, Williams
openaire   +2 more sources

Scavenger Receptors, Oxidized LDL, and Atherosclerosis

Annals of the New York Academy of Sciences, 2001
Abstract: Oxidized LDL (OxLDL) competes with oxidatively damaged and apoptotic cells for binding to mouse peritoneal macrophages, implying the presence of one or more common domains. However, the nature of the ligands involved has not been determined.
A, Boullier, D A, Bird, M K, Chang, E A, Dennis, P, Friedman, K, Gillotre-Taylor, S, Hörkkö, W, Palinski, O, Quehenberger, P, Shaw, D, Steinberg, V, Terpstra, J L, Witztum   +12 more
openaire   +2 more sources

Scavenger receptor Bl and cholesterol trafficking

Current Opinion in Lipidology, 1999
Scavenger receptor BI (SR-BI) mediates the selective uptake of HDL cholesteryl ester into steroidogenic cells and the liver and is a major determinant of the plasma HDL concentration in the mouse. Recent studies indicate that SR-BI also alters the metabolism of apolipoprotein B-containing particles and influences the development of atherosclerosis in ...
D L, Williams, M A, Connelly, R E, Temel, S, Swarnakar, M C, Phillips, M, de la Llera-Moya, G H, Rothblat   +6 more
openaire   +2 more sources

[Scavenger receptor family].

Nihon rinsho. Japanese journal of clinical medicine, 2000
After the proposal of scavenger pathway hypothesis, a family of genes have been discovered. Here we show the precise properties of the first cloned scavenger receptor class A type I and II. Then the profiles of other members of scavenger receptors including lectin receptors are shown briefly.
T, Kohro, A, Sugiyama, Y, Wada, T, Kodama   +3 more
openaire   +1 more source