Results 241 to 250 of about 53,181 (303)

The ectodomains of the lymphocyte scavenger receptors CD5 and CD6 interact with tegumental antigens from Echinococcus granulosus sensu lato and protect mice against secondary cystic echinococcosis. [PDF]

PLoS Negl Trop Dis, 2018
Mourglia-Ettlin G, Miles S, Velasco-De-Andrés M, Armiger-Borràs N, Cucher M, Dematteis S, Lozano F.   +6 more
europepmc   +1 more source

DNase I‐Mediated Chemotactic Nanoparticles for NETs Targeting and Microenvironment Remodeling Treatment of Acute Ischemic Stroke

Advanced Science, EarlyView.
The neutrophil extracellular traps (NETs) play an important role in reperfusion injury in ischemic stroke. Here, considering the unique vascular localization of NETs, a DNase I‐mediated NETs‐targeting nanoparticle is developed to integrate the catalytic and chemotactic functions of DNase I and achieve the synergistic regulation of the internal and ...
Tongyu Zhang, Peixin Liu, Wenru Shen, Chao Li, Zhenhao Zhao, Yuxing Wu, Tao Sun, Chen Jiang   +7 more
wiley   +1 more source

Autophagy regulates phagocytosis by modulating the expression of scavenger receptors. [PDF]

Immunity, 2013
Bonilla DL, Bhattacharya A, Sha Y, Xu Y, Xiang Q, Kan A, Jagannath C, Komatsu M, Eissa NT.   +8 more
europepmc   +1 more source

Reduced Atherosclerotic Lesions in Mice Deficient for Total or Macrophage-Specific Expression of Scavenger Receptor-A

, 2000
Vladimir R. Babaev, Linda A. Gleaves, Kathy J. Carter, Hiroshi Suzuki, Tatsuhiko Kodama, Sergio Fazio, MacRae F. Linton   +6 more
openalex   +1 more source

Near‐Infrared Afterglow Imaging‐Guided Surgical Resection and Synergistic Photodynamic‐Chemo Therapy of Breast Cancer

Advanced Science, EarlyView.
A CDSP NPs theranostic platform assembled from CDs and paclitaxel prodrugs is developed. CDSP NPs have long‐lasting NIR afterglow, penetrate deep tissues, and offer a high signal‐to‐noise ratio, enabling NIR afterglow imaging‐guided precise breast cancer removal to prevent recurrence.
Zixuan Li, Ranran Zhao, Qing Pei, Zhigang Xie, Min Zheng   +4 more
wiley   +1 more source

Bioinspired Claw‐Engaged Adhesive Microparticles Armed with γGC Alleviate Ulcerative Colitis via Targeted Suppression of Macrophage Ferroptosis

Advanced Science, EarlyView.
γGC deficiency in ulcerative colitis drives macrophage ferroptosis‐mediated inflammation. Claw‐engaged microparticles armed with γGC (γGC‐MPs) enhance lesion targeting, promoting localized γGC release and tissue uptake. On the cover, Monkey King (Macrophages) was bound by the Immortal‐Binding Rope and subsequently sealed beneath the Five‐Fingered ...
Rong Wang, Jianwei Zhu, Jinyi Zhou, Jinyang Li, Min Wang, Yuqi Wu, Danshan Zhao, Xiancheng Chen, Xiaoyuan Chen, Yuetong Wang, Jianhua Zou   +10 more
wiley   +1 more source

An Off‐the‐Shelf Artificial Blood Clot Hydrogel Neutralizing Multiple Proinflammatory Mediators for Pro‐Regenerative Periodontitis Treatment

Advanced Science, EarlyView.
CCS‐RSF@PRP hydrogel is engineered to structurally and functionally mimic the blood clot by integrating PPR, CCS, and RSF nanofibers through in situ activation of PRP. In a rat periodontitis model, CCS‐RSF@PRP hydrogel effectively promotes periodontal tissue repair, attributing to neutralizing the multiple proinflammatory mediators, thus rebuilding a ...
Yini Huangfu, Zhezhe Zhao, Xiang Liu, Jingrong Wang, Yufeng Zhang, Tingting Lan, Yonglan Wang, Chenxuan Wu, Ju Zhang, Pingsheng Huang, Chuangnian Zhang, Anjie Dong, Zujian Feng, Deling Kong, Weiwei Wang   +14 more
wiley   +1 more source

Bimetallic Plasmonic Nanozyme‐Based Microneedle for Synergistic Ferroptosis Therapy of Melanoma

Advanced Science, EarlyView.
A microneedle (MN) patch that integrates novel bimetallic plasmonic nanozyme (BPNzyme) and traditional Chinese medicine β‐elemene (β‐ELE) has been rationally designed for ferroptosis pathway‐dependent combined therapy of melanoma. Abstract Melanoma is the most common malignant skin tumor, characterized by complexity, invasiveness, and heterogeneity ...
Wei Duan, Keying Xu, Yue Gao, Sheng Huang, Xueqian Xia, Xiang Liu, Shuangxue Pan, Chunpeng Jiao, Weijian Cheng, Yong Guo, Jingwen Zhao, Jia‐Wei Shen   +11 more
wiley   +1 more source

Targeting Neutrophil/Eosinophil Extracellular Traps by Aptamer‐Functionalized Nanosheets to Overcome Recalcitrant Inflammatory Disorders

Advanced Science, EarlyView.
In this study, C‐TAH, as multifunctional nanosheets, is developed with tannic acid and histone aptamer coverage. C‐TAH displays mild cytotoxicity, robust dsDNA and NETs/EETs binding efficiency, and potent antioxidant and antibacterial ability in vitro. C‐TAH treatment ameliorates dysregulated inflammation and restores hearing function in animal models,
Yongqiang Xiao, Xinyue Wang, Ming Liu, Xiao Fu, Nanfeng Zhang, Wenqing Yang, Junyi Ge, Yangyang Li, Duan Ma, Jing Ma, Weiping Wen, Dongdong Ren, Tianyu Zhang, Zhaoxu Tu   +13 more
wiley   +1 more source

A Tailored Artificial Biocatalyst for Bacterial Endophthalmitis Therapy via Enhanced Ferroptosis‐Like Death

Advanced Science, EarlyView.
A tailored bio‐targeted catalytic strategy based on a bacteria‐specific artificial biocatalyst (MoS2/Fe@mercaptophenylboronic acid@hyaluronic acid, MFBH) is proposed for treating bacterial endophthalmitis. This strategy exhibits high‐efficiency peptidoglycan‐targeted bactericidal efficacy in vivo following a single intravitreal injection of an ...
Caixia Sun, Yingying Jiang, Shibo Zhang, Zhipeng Ding, Lijun Pu, Xinmei Liu, Jun Yang, Xiangkai Zhuge, Jianjun Dai, Yanmin Ju   +9 more
wiley   +1 more source