Results 251 to 260 of about 53,683 (320)

Synthesis, Optical and Singlet Oxygen Generation Properties of Phenazinone‐Based Photosensitizer with 5‐Formyl‐2‐Thienyl Substituents

open access: yesAsian Journal of Organic Chemistry, EarlyView.
Phenazinone chromophore incorporating a carbonyl group into the skeleton is recently found to be a new‐type halogen‐atom‐free‐photosensitizer possessing superior ability in singlet oxygen (1O2) generation. In this work, we have designed and developed the derivative with two 5‐formyl‐2‐thienyl substituents which is expected to lead to improvement of the
Hiroto Tsuyama   +2 more
wiley   +1 more source

Effects of scavenger receptors-1 class A stimulation on macrophage morphology and highly modified advanced glycation end product-protein phagocytosis. [PDF]

open access: yesSci Rep, 2018
Hamasaki S   +9 more
europepmc   +1 more source

The tau isoform 1N4R confers vulnerability of MAPT knockout human iPSC‐derived neurons to amyloid beta and phosphorylated tau‐induced neuronal dysfunction

open access: yesAlzheimer's &Dementia, EarlyView.
Abstract INTRODUCTION Human tau protein, composed of six brain‐specific isoforms, is a major driver of Alzheimer's disease (AD). The role of its isoforms however remains unclear and human AD models are scarce. METHODS We generated human MAPT– (tau–) knockout (KO) induced pluripotent stem cells (iPSC) using CRISPR/Cas9, differentiated these into ...
Sarah Buchholz   +11 more
wiley   +1 more source

Mesenchymal stem cells internalize Mycobacterium tuberculosis through scavenger receptors and restrict bacterial growth through autophagy. [PDF]

open access: yesSci Rep, 2017
Khan A   +10 more
europepmc   +1 more source

Targeting signaling pathways in neurodegenerative diseases: Quercetin's cellular and molecular mechanisms for neuroprotection

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Quercetin regulates signaling pathways in neurodegenerative diseases, including NF‐κB, sirtuins, and PI3K/Akt. Studies show quercetin improves symptoms and pathology in neurodegenerative models. The study aims to incorporate laboratory research into practical medical treatment, focusing on quercetin's neuroprotective effects and optimal dosage ...
Md. Rezaul Islam   +13 more
wiley   +1 more source

Sugar‐sensing swodkoreceptors and swodkocrine signaling

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Sugar‐sensing swodkoreceptors that trigger swodkocrine signaling. Abstract Sugars are one of the major metabolites and are essential for nucleic acid synthesis and energy production. In addition, sugars can act as signaling molecules. To study sugar signaling at the systemic level, there is an urgent need to systematically identify sugar‐sensing ...
Savani Anbalagan
wiley   +1 more source

Kinetic Redox Shotgun Proteomics Reveals Specific Lipopolysaccharide Effects on Intestinal Epithelial Cells, Mitigated by a Mn Superoxide Dismutase Mimic

open access: yesAngewandte Chemie, EarlyView.
Proteomics and redoxomics are efficient to quantify the effects of bacterial lipopolysaccharide in intestinal epithelial cells (HT29) at the proteome and at the Cys‐redoxome levels. Oxidative stress is the initial trigger of LPS leading to inflammation.
Martha Zoumpoulaki   +14 more
wiley   +2 more sources

Intestinal scavenger receptors are involved in vitamin K1 absorption. [PDF]

open access: yesJ Biol Chem, 2014
Goncalves A   +7 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy