Results 61 to 70 of about 55,768 (280)
Macrophage Scavenger Receptor Class A [PDF]
Abstract—In atherogenesis, elevated plasma levels of low density lipoprotein (LDL) lead to the chronic presence of LDL in the arterial wall. There, LDL is modified (eg, oxidized), and these modified lipoproteins activate endothelial cells, which attract circulating monocytes.
Winther, M.P.J. de +3 more
openaire +3 more sources
This research presents a novel implantable bio‐battery, GF‐OsG, tailored for diabetic bone repair. GF‐OsG generates microcurrents in high‐glucose conditions to enhance vascularization, shift macrophages to the M2 phenotype, and regulate immune responses.
Nanning Lv +10 more
wiley +1 more source
Polymorphism of class A scavenger receptors in C57BL/6 mice1
Scavenger receptors class A (SR-A) have been hypothesized to regulate the development of atherosclerotic lesions through recognition of modified low density lipoprotein (LDL) and macrophage adhesion to substrata.
Alan Daugherty +3 more
doaj +1 more source
The pyrene and ether groups are incorporated into the covalent triazine polymer (CTP) structure. The synergistic effect of the two functional groups endows CTP with better electron transfer, light absorption, and oxygen activation properties. An impressive apparent quantum yield (13.2% @420 nm) and a remarkable solar‐to‐chemical conversion efficiency ...
Chong Wang +10 more
wiley +1 more source
Macrophages are a diverse group of phagocytic cells acting in host protection against stress, injury, and pathogens. Here, we show that the scavenger receptor SR-A6 is an entry receptor for human adenoviruses in murine alveolar macrophage-like MPI cells,
Nicole Stichling +13 more
doaj +1 more source
The hydrophobic tunnel present in LOX-1 is essential for oxidized LDL recognition and binding
Lectin-like oxidized LDL (ox-LDL) receptor-1 (LOX-1) is a type-II transmembrane protein that belongs to the C-type lectin family of molecules. LOX-1 acts as a cell surface endocytosis receptor and mediates the recognition and internalization of ox-LDL by
Omar L. Francone +10 more
doaj +1 more source
Scavenger Receptors in Atherosclerosis [PDF]
The existence of a cell surface receptor, now known as the macrophage scavenger receptor A I/II (MSR-A), was inferred from early studies based on ligand binding analyses. Description of this binding activity, with acetylated low density lipoprotein (LDL) used as a ligand, was important because it provided a mechanism for the formation of foam cells in ...
openaire +1 more source
A minimally invasive, transepithelial corneal cross‐linking (TE‐CXL) approach is presented using upconversion nanoparticles (UCNPs)‐loaded contact lenses (UCLs), after topical delivery of hyaluronate–riboflavin conjugates. The NIR‐to‐UV/blue light conversion by UCNPs in a UCL can activate riboflavin for TE‐CXL, resulting in the biomechanical strength ...
Gibum Lee +8 more
wiley +1 more source
Modulation of macrophage scavenger receptor transport by protein phosphorylation
The identification of three highly conserved phosphorylation sites in the cytoplasmic domain of each of the monomeric subunits of the macrophage scavenger receptor suggests that protein phosphorylation may regulate this receptor pathway.
L G Fong
doaj +1 more source
Oxidation by neutrophils-derived HOCl increases immunogenicity of proteins by converting them into ligands of several endocytic receptors involved in antigen uptake by dendritic cells and macrophages. [PDF]
The initiation of adaptive immune responses to protein antigens has to be preceded by their uptake by antigen presenting cells and intracellular proteolytic processing.
Rafał Biedroń +3 more
doaj +1 more source

