Results 61 to 70 of about 1,235,706 (276)

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Application of index of entropy and Geospatial techniques for landslide prediction in Lunglei district, Mizoram, India

open access: yesNatural Hazards Research, 2023
The present study focuses on developing a landslide susceptibility zonation (LSZ) using GIS-based bivariate statistical model in the Lunglei district of Mizoram. Initially, 17 factors were selected after calculating the multicollinearity test for LSZ.
Jonmenjoy Barman   +3 more
doaj   +1 more source

Semi-device-independent security of one-way quantum key distribution

open access: yes, 2011
By testing nonlocality, the security of entanglement-based quantum key distribution (QKD) can be enhanced to being 'device-independent'. Here we ask whether such a strong form of security could also be established for one-way (prepare and measure) QKD ...
Brunner, Nicolas, Pawlowski, Marcin
core   +1 more source

Review of local non-Gaussianity from multi-field inflation [PDF]

open access: yes, 2010
We review models which generate a large non-Gaussianity of the local form. We first briefly consider three models which generate the non-Gaussianity either at or after the end of inflation; the curvaton scenario, modulated (p)reheating and an ...
Byrnes, Christian T., Choi, Ki-Young
core   +4 more sources

Scenario-based stress tests: are they painful enough?

open access: yesContemporary Economics, 2017
Forecasts, models and stress tests are important tools for policymakers and business planners. Recent developments in these related spheres have seen greater emphasis placed on stress tests from a regulatory perspective, while at the same time forecasting performance has been criticized.
openaire   +2 more sources

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

open access: yesMolecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia   +9 more
wiley   +1 more source

High speed self-testing quantum random number generation without detection loophole

open access: yes, 2017
Quantum mechanics provides means of generating genuine randomness that is impossible with deterministic classical processes. Remarkably, the unpredictability of randomness can be certified in a self-testing manner that is independent of implementation ...
Cao, Yuan   +19 more
core   +1 more source

Outlook for tuberculosis elimination in California: An individual-based stochastic model. [PDF]

open access: yes, 2019
RationaleAs part of the End TB Strategy, the World Health Organization calls for low-tuberculosis (TB) incidence settings to achieve pre-elimination (<10 cases per million) and elimination (<1 case per million) by 2035 and 2050, respectively. These
Barry, Pennan M   +10 more
core   +3 more sources

ISS-Scenario: Scenario-Based Testing in CARLA

open access: yes
The rapidly evolving field of autonomous driving systems (ADSs) is full of promise. However, in order to fulfil these promises, ADSs need to be safe in all circumstances. This paper introduces ISS-Scenario, an autonomous driving testing framework in the paradigm of scenario-based testing.
Renjue Li   +2 more
openaire   +2 more sources

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

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