Results 161 to 170 of about 59,530 (304)

From HBV to MASLD Cirrhosis: Mechanistic Insights and Therapeutic Strategies

Portal Hypertension &Cirrhosis, EarlyView.
This review examines the epidemiological shift from hepatitis B virus (HBV) to metabolic dysfunction‐associated steatotic liver disease (MASLD) as the leading cause of cirrhosis globally. It highlights the distinct pathogenic mechanisms between HBV and MASLD cirrhosis and discusses evolving diagnostic tools and therapeutic strategies tailored to the ...
Hanqi Yu, Hongfan Ding, Yang Huang, Haoze Cao, Yuan Ding, Weilin Wang   +5 more
wiley   +1 more source

The Role of Changes in the Proportion of Fecal Short-Chain Fatty Acids on the Severity of Hepatic Encephalopathy in Cirrhosis Patients

Acta Medica Indonesiana
Background: Short-chain fatty acids (SCFA) are the main metabolites of the intestinal microbiota, which play a role as colonocyte trophic factors and maintain the integrity of the gastrointestinal tract and blood-brain barrier. Microbiota dysbiosis that
Mochamad Anief Ferdianto, Juferdy Kurniawan, Hasan Maulahela, Cleopas Martin Rumende, Imam Subekti, Ikhwan Rinaldi, Hamzah Shatri, Cosmas Rinaldi Lesmana   +7 more
doaj   +2 more sources

Exploring the Gut‐Prostate Axis: Microbial Signatures Linked to Prostate Volume and Bladder Function

The Prostate, EarlyView.
ABSTRACT Background Benign prostatic hyperplasia (BPH) is a common urologic condition in aging men, often linked to systemic inflammation and metabolic dysfunction. Emerging evidence suggests that the gut microbiome may contribute to prostate health and disease.
Jonathan Surber, Marie Lork, Yasser Morsy, Michael Scharl, Daniel Stephan Engeler, Janine Langenauer, Lukas John Hefermehl, Anna Ebner, Basil Kaufmann, Manuela Hunziker, Daniel Eberli, Uwe Bieri, Cédric Poyet   +12 more
wiley   +1 more source

The evolving role of regulatory T cells in Sjögren's disease pathogenesis and the promise of Treg‐based therapies: A comprehensive review

Rheumatology &Autoimmunity, EarlyView.
Graphical Abstract The evolving role of regulatory T cells in primary Sjögren's disease pathogenesis and the promise of Treg‐based therapies. Abstract Sjögren's disease (SjD) is a chronic systemic autoimmune disorder characterised by exocrine gland dysfunction and diverse systemic manifestations.
Gagan Urs, Bharath Raj Srinivasan, Himabindu Jayaprakash Narayan, Mirunalini Gobinath, Lekitha Manjunath, Mahabaleshwar Mamadapur   +5 more
wiley   +1 more source

The microbial peace-signal hypothesis: distributed immune "peace hubs" across the human body. [PDF]

Front Immunol
Han CS.
europepmc   +1 more source

Inulin‐Butyrate Nanogel for Modulation of Gut Microbiome, Intestinal Barrier, and Regulatory T‐Cells in Colitis

Small, EarlyView.
ABSTRACT Inflammatory bowel diseases (IBD) arise from a vicious cycle of intestinal barrier dysfunction, gut microbiome dysbiosis, and dysregulated immune responses. Current therapies predominantly suppress immunity but fail to address root causes or break this cycle.
Nayoon Park, Bom Lee, Hyeon‐Jeong Jeon, Ji Yeon Kim, Suyeon Park, Seong‐Eun Kim, Dong‐Kyu Lee, Yonghyun Lee   +7 more
wiley   +1 more source

The Role of Butyrate in People with Metabolic Dysfunction-Associated Steatotic Liver Disease and Related Metabolic Comorbidities: A Systematic Review. [PDF]

Curr Obes Rep
González-González A, Soria-Utrilla V, Fontalba-Romero MI, Núñez-Sánchez MÁ, Adarve-Castro A, Queipo-Ortuño MI, Ramos-Molina B, Martínez-Montoro JI, Fernández-García JC.   +8 more
europepmc   +1 more source

Sex‐Specific Involvement of Gut Microbiota in Behavioral and Endocrine Responses to Chronic Predator Odor in Brandt's Voles

Integrative Zoology, EarlyView.
18 days of predator odor exposure altered gut microbiota, increased anxiety‐like behaviors, and elevated hypothalamic–pituitary–adrenal axis activity in Brandt's voles, with males showing behavioral habituation and females remaining sensitive. Cecal microbiota transplantation experiments confirmed that only female recipients of microbiota from predator‐
Chen Gu, Ruiping Xu, Baofa Yin, Ruiyong Wu, Youheng Wei, Dehua Wang, Wanhong Wei   +6 more
wiley   +1 more source

Gut microbiota metabolites positively impacts chemotherapy effects in colorectal cancer. [PDF]

Cell Biol Toxicol
Gomes S, Granja S, Osório LA, Mackay RE, Baltazar F, Silva E, Preto A.   +6 more
europepmc   +1 more source

Comparison of Three Sympatric Desert Lizards: Digestive Tract Structure, Digestive Enzyme Activities, Gut Microbiota, and Metabolites

Integrative Zoology, EarlyView.
We performed 16S rDNA sequencing and metabolite profiling for three sympatric lizard species—Teratoscincus roborowskii, Phrynocephalus axillaris, and Eremias roborowskii—and compared their goblet cell and enzyme activities in the digestive tract. Our study suggests that the dietary niche may promote divergence or convergence of microbiota across host ...
Yi Yang, Ziyi Wang, Ruichen Wu
wiley   +1 more source