Results 261 to 270 of about 59,530 (304)

In Vitro Gastrointestinal Digestion and Microbial Hydrolysis of Hydroxytyrosol-SCFA and Tyrosol-SCFA Acyl Esters: Controlled-Release of SCFAs and Polyphenols

Journal of Agricultural and Food Chemistry, 2023
Phenolipids such as hydroxytyrosol-SCFA acyl esters (HTy-SEs) and tyrosol-SCFA acyl esters (TYr-SEs) with various alkyl chains lengths (C1-C4) and different isomers (branched-chain and straight-chain) were successfully synthesized. All esters were hydrolyzed by pancreatic lipase to produce polyphenols (HTy and TYr) and SCFAs (iso-butyric acid, acetic ...
Xinmiao Wang, Qian Wang, Dong Cai, Xu Guo, Peiyong Tong, Fawen Yin, Xiaoyang Liu, Dayong Zhou   +7 more
openaire   +2 more sources

Microbiota and SCFA in Lean and Overweight Healthy Subjects [PDF]

Obesity, 2010
Obesity has recently been linked to the composition of human microbiota and the production of short chain fatty acids (SCFAs). However, these findings rely on experimental studies carried out using rather small and defined groups of volunteers or model animals.
Andreas Schwiertz, David Taras
exaly   +4 more sources

SCFA Transport in the Forestomach of Ruminants

Comparative Biochemistry and Physiology Part A: Physiology, 1997
Short-chain fatty acids are the main end-products of microbial metabolism in the forestomach of ruminants. SCFA produced by the microorganisms are rapidly absorbed across forestomach epithelia and can cover up to 80% of the energy requirement of the animal.
G, Gäbel, J, Sehested
openaire   +2 more sources

Presence of airway SCFAs in asthma and response of airway epithelium to SCFAs

Airway cell biology and immunopathology, 2019
Background: Gut microbial fermentation products, short-chain fatty acids (SCFAs) have recently been described to play a beneficial role in asthma and allergic airway inflammation. The mechanisms behind this remain partly unclear. Aims: To investigate presence of SCFAs in airway fluids of healthy controls and people with asthma and the effect of SCFAs ...
Marianne Koliana, Ernie Wong, David J. Jackson, Tatiana Kebadze, Carine Blanchard, Sebastian L. Johnston, Elaine Holmes, Gary Frost   +7 more
openaire   +1 more source

Dietary fiber and SCFAs in the regulation of mucosal immunity

Journal of Allergy and Clinical Immunology, 2023
Gut bacterial metabolites such as short-chain fatty acids (SCFAs) have important effects on immune cells and the gut. SCFAs derive from the fermentation of dietary fiber by gut commensal bacteria. Insufficient fiber intake thus compromises SCFA production and, as a consequence, the host's physiology (particularly immune functions). We propose that many
Jian Kai, Tan, Laurence, Macia, Charles R, Mackay   +2 more
openaire   +2 more sources

Ruminal transport and metabolism of short-chain fatty acids (SCFA) in vitro: effect of SCFA chain length and pH

Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology, 1999
The unidirectional transport and metabolism of 14C-labeled acetate, propionate and butyrate across the isolated bovine rumen epithelium was measured in vitro by the Ussing chamber technique. There was a significant, but relatively small, net secretion of acetate and propionate, and a large and significant net absorption of butyrate.
Sehested, J., Diernæs, L., Møller, P. D., Skadhauge, E.   +3 more
openaire   +2 more sources

Dietary SCFAs Immunotherapy: Reshaping the Gut Microbiota in Diabetes

2020
Diet-microbiota related inflammatory conditions such as obesity, autoimmune type 1 diabetes (T1D), type 2 diabetes (T2D), cardiovascular disease (CVD) and gut infections have become a stigma in Western societies and developing nations. This book chapter examines the most relevant pre-clinical and clinical studies about diet-gut microbiota approaches as
Yu Anne, Yap, Eliana, Mariño
openaire   +2 more sources

Tu1557: DIETARY OXYLIPIN REDUCES SCFA PRODUCING GUT BACTERIA AND SCFA SUPPLEMENTATION PREVENTS OXYLIPIN INDUCED PULMONARY HYPERTENSION

Gastroenterology, 2022
Ellen O'Connor, Gregoire Ruffenach, Victor Grijalva, Alan Fogelman, Mansoureh Eghbali, Srinivasa Reddy   +5 more
openaire   +1 more source

SCFAs: The Enigma of Weak Electrolyte Transport in the Colon

Physiology, 1999
Short-chain fatty acids are the predominant luminal anions in the colon (>75 mM) and thus create a rather unique environment for transporting epithelium. The colon absorbs short-chain fatty acids, either by diffusion of the protonated species across the apical membrane or by an anion exchange process with bicarbonate.
openaire   +2 more sources

SCFAs — the thin microbial metabolic line between good and bad

Nature Reviews Endocrinology, 2019
By combining genetic, metagenomic and metabolic data in humans, a recent study has identified causal relationships between the capacity of gut microorganisms to produce short-chain fatty acids, such as butyrate and propionate, and metabolic traits of the host, including insulin response during an oral glucose tolerance test and susceptibility to type 2
openaire   +4 more sources