Results 71 to 80 of about 59,530 (304)

A Precision Microbiome Approach Using Sucrose for Selective Augmentation of Staphylococcus epidermidis Fermentation against Propionibacterium acnes. [PDF]

, 2016
Acne dysbiosis happens when there is a microbial imbalance of the over-growth of Propionibacterium acnes (P. acnes) in the acne microbiome. In our previous study, we demonstrated that Staphylococcus epidermidis (S. epidermidis, a probiotic skin bacterium)
Gallo, Richard L, Huang, Chun-Ming, Huang, Stephen, Kao, Ming-Shan, Marito, Shinta, Wang, Yanhan, Yu, Jinghua   +6 more
core   +2 more sources

Gut microbial metabolites SCFAs and chronic kidney disease

Journal of Translational Medicine
AbstractThe global incidence of Chronic Kidney Disease (CKD) is steadily escalating, with discernible linkage to the intricate terrain of intestinal microecology. The intestinal microbiota orchestrates a dynamic equilibrium in the organism, metabolizing dietary-derived compounds, a process which profoundly impacts human health.
Meng He, Wenqian Wei, Yichen Zhang, Zhouxia Xiang, Dan Peng, Ayijiaken Kasimumali, Shu Rong   +6 more
openaire   +3 more sources

Do SCFA have a role in appetite regulation? [PDF]

Proceedings of the Nutrition Society, 2011
The recently discovered SCFA-activated G-coupled protein receptors FFA receptor 2 and FFA receptor 3 are co-localised inl-cells with the anorexigenic ‘ileal brake’ gut hormone peptide YY, and also in adipocytes, with activation stimulating leptin release.
Darzi, J, Frost, GS, Robertson, MD
openaire   +3 more sources

Multicohort Validation of Gut Microbiome Signatures for Cholangiocarcinoma Diagnosis and Functional Characterization of Bifidobacterium Pseudocatenulatum

Advanced Science, EarlyView.
This study analyzes gut bacteria in cholangiocarcinoma patients, revealing distinct microbial signatures that enable accurate disease detection. Species‐based diagnostic models achieved over 98% accuracy in identifying cholangiocarcinoma and distinguished it from other liver diseases. The research demonstrates that specific beneficial bacteria suppress
Benchen Rao, Jianwen Jiang, Ruiqing Zhang, Dongya Zhang, Chenchen Zhang, Ang Li, Haifeng Lu, Hua Zhang, Lin Zhou, Wenzhi Guo, Peihao Wen, Jianfeng Xue, Jie Pan, Tuerganaili Aji, Zhou Lan, Xianzhi Jiang, Shusen Zheng, Zujiang Yu, Zhigang Ren   +18 more
wiley   +1 more source

Relationship Between Short Chain Fatty Acids and Menarche in Elementary School Students in Padang City

Andalas Obstetrics and Gynecology Journal
Introduction: Early menarche is associated with long-term health problems. Currently, adolescent girls are increasingly experience the change of menarche age.
Zulfiqar MS, Haviz Yuad, Husna Yetti, Defrin Defrin, Ferdinal Ferry, Mondale Saputra   +5 more
doaj   +1 more source

The mPEG-PCL Copolymer for Selective Fermentation of Staphylococcus lugdunensis Against Candida parapsilosis in the Human Microbiome. [PDF]

, 2016
Many human skin diseases, such as seborrheic dermatitis, potentially occur due to the over-growth of fungi. It remains a challenge to develop fungicides with a lower risk of generating resistant fungi and non-specifically killing commensal microbes.
Barshop, Bruce A, Chen, Wan-Tzu, Gallo, Richard L, Gangoiti, Jon A, Hsieh, Ming-Fa, Huang, Chun-Jen, Huang, Chun-Ming, Huang, Stephen, Hyun, Choi, Kao, Ming-Shan, Lee, Woan-Ruah, Lin, Wan-Zhen, Marito, Shinta, Ran, Yuping, Sanford, James A, Wang, Yanhan   +15 more
core   +1 more source

Aspek Fisiologik Short Chain Fatty Acid (SCFA)

Medical Scope Journal, 2020
Abstract: Consumption of fiber-rich diet and undigested carbohydrate is very beneficial in the maintance of optimal health and control of metabolic and cardiovascular diseases. Short chain fatty acid (SCFA) is an end-product of carbohydrate and protein fermented by gut microbiota.
openaire   +3 more sources

Oncolytic Probiotics with Molecular Pili for Solid Tumor Therapy

Advanced Science, EarlyView.
This study identifies Lactobacillus rhamnosus as an intrinsic oncolytic agent that triggers tumor metabolic collapse via calcium‐dependent ROS bursts. By chemically anchoring collagen‐targeting “molecular pili” to the bacterial surface, the engineered non‐transgenic probiotic (LR@MP) achieves targeted colonization and potent solid tumor suppression ...
Haodong Ge, Chengsheng Ding, Xiao Yang, Si Gao, Changjie Yang, Yuchen Hou, Hongye Wang, Linke Bian, Hao Zhong, Yifan Qu, Luyang Zhang, Junjun Ma, Zhengwei Cai, Wenguo Cui, Minhua Zheng   +14 more
wiley   +1 more source

The effects of dietary fibre type on satiety-related hormones and voluntary food intake in dogs [PDF]

, 2009
Depending on type and inclusion level, dietary fibre may increase and maintain satiety and postpone the onset of hunger. This 7-week study evaluated the effect of fibre fermentability on physiological satiety-related metabolites and voluntary food intake
Bosch, G., Hendriks, W.H., Hesta, M., Holst, J.J., Janssens, G.P.J., Poel, A.F.B., van der, Verbrugghe, A.   +6 more
core   +2 more sources

T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities

Advanced Science, EarlyView.
T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu, Xiaoyu Yao, Qingyang Wang, Mengrui Yang, Runze Li, Jiangjiang Qin, Jing Zhuang, Changgang Sun   +7 more
wiley   +1 more source