Results 51 to 60 of about 51,375 (256)

Bioengineered Exosome‐Loaded Immunomodulatory Bioadhesive Spray Reverses Liver Fibrosis and Metabolic Dysfunction That Triggers Beneficial Gut‐Liver Crosstalk in Chronic Fatty Liver Disease

Advanced Science, EarlyView.
Umbilical cord stem cell‐derived exosomes encapsulated in an immunomodulatory bioadhesive hydrogel spray enable localized therapy, sustained vesicle delivery, macrophage polarization, suppress systemic inflammation, and mitigate glucose and insulin homeostasis impairments in MAFLD.
Triya Saha, Ayushi Mairal, Shreya Mehrotra, Shiv K. Sarin, Ashok Kumar   +4 more
wiley   +1 more source

Fecal content of SCFA in rats (μmol/g).

, 2016
Fecal content of SCFA in rats (μmol/g).
Xiangjun Sun (2812708), Kefeng Ni (151445), Liangli Yu (2036122), Songyou Hu (3270141), Jianchun Wan (3270135), Guifang Chang (3270138)   +5 more
core   +1 more source

Probiotic‐Derived Vesicles Rectally Delivered via Thermo‐Gelling Copolymer Promote Mucosal Healing and Reduce Inflammation in Ulcerative Colitis

Advanced Science, EarlyView.
A thermo‐responsive rectal delivery platform integrating probiotic‐derived extracellular vesicles within a hyaluronic acid‐based copolymer enables localized and sustained therapy for ulcerative colitis. The formulation effectively suppresses inflammation, promotes macrophage polarization toward a regenerative phenotype, restores epithelial barrier ...
Ayushi Mairal, Ubaid Tariq, Shreya Mehrotra, Saravanan Matheshwaran, Jan Marsal, Ashok Kumar   +5 more
wiley   +1 more source

Effect of xylo-oligosaccharides and β-glucan on gut microbiota and short chain fatty acid in diabetic rats

Journal of Advanced Biotechnology and Experimental Therapeutics
Obesity and type 2 diabetes mellitus (T2DM) have an impact on an imbalance in the number of microbiota (dysbiosis) which can cause disruption of glucose metabolism by inhibiting short chain fatty acid (SCFA).
Iftita Elok Zahara, Endang Mahati, Mohammad Sulchan, Adriyan Pramono, Achmad Zulfa Juniarto   +4 more
doaj   +1 more source

Fecal levels of SCFA and BCFA during capecitabine in patients with metastatic or unresectable colorectal cancer

, 2023
BackgroundGut bacteria-derived short-chain fatty acids (SCFA) and branched-chain fatty acids (BCFA) are considered to have beneficial metabolic, anti-inflammatory as well as anti-carcinogenic effects.
de Vos-Geelen, J., Baars, A., Ziemons, J., Waelen, J., Penders, J., Vestjens, J.H.M.J., Aarnoutse, R., Iersel, L.V.V., Heuft, A., Hillege, L., van Hellemond, I.E.G., Smidt, M.L., Ziemons, J.; id_orcid, Creemers, G.J.M., Venema, K.   +14 more
core   +1 more source

Chemoselective Metabolomics via a Modular Reactivity‐Encoding Platform

Advanced Science, EarlyView.
Conventional LC–MS underrepresents numerous metabolites due to heterogeneous ionization efficiencies and matrix interference. Here, we introduce a modular reactivity‐encoding platform (MREP) comprising four alkyne‐tagged probes that selectively derivatize key functional groups, followed by unified click‐chemistry capture to eliminate matrix components ...
Xin Tao, Cang‐Man Zhang, Ru‐Jie Yang, Min Ren, Zhuo‐Ling Zhong, Kang‐Hui Wang, Rui‐Xue Hu, Jia‐Yue Liu, Jun‐Yi Zhou, Hou‐Kai Li, Jian‐Bo Wan   +10 more
wiley   +1 more source

Arterial SCFA concentrations before and after resection (n = 30).

, 2016
Arterial SCFA concentrations before and after resection (n = 30).
Sander S. Rensen (292951), Evelien P. J. G. Neis (3344087), Johanne G. Bloemen (3344081), Maartje A. van den Broek (3344084), Cornelis H. C. Dejong (212853), Koen Venema (260576), Joost R. van der Vorst (3344090), Wim A. Buurman (162734)   +7 more
core   +1 more source

Disrupting Helicobacter pylori Iron Homeostasis With Bismuth Nanodrug‐Mediated Nutritional Trap for Targeted Gastric Infection Therapy

Advanced Science, EarlyView.
A “nutritional trap” strategy centered on disrupting bacterial iron homeostasis is proposed. The synthesized Bi‐TP@FU (TBF) can target Helicobacter pylori, interfere with the bacterial iron uptake and utilization processes to disrupt its iron homeostasis, induce bacterial death, and meanwhile preserve the balance of the intestinal flora.
Tianye Fang, Jinzhe Tong, Feng Feng, Cong Liu, Chang Shu, Jiaying Zhu, Shibo Zhang, Shuyue Deng, Wanchao Zuo, Yuhan Song, Jun Yang, Yanmin Ju, Yingying Xing, Jianjun Dai   +13 more
wiley   +1 more source

The modulation of intestinal barrier integrity in broiler chickens is associated with the microbiome changes

Біологія тварин
Cell adhesion proteins play a crucial role in ensuring the barrier function of the intestinal epithelium by forming intercellular tight junctions that prevent the invasion of harmful substances, microorganisms, and toxins into the organism’s internal ...
L. M. Tamchuk, D. M. Masiuk
doaj   +1 more source

Table_1_Sources of Dietary Fiber Affect the SCFA Production and Absorption in the Hindgut of Growing Pigs.docx

, 2022
Effects of different dietary fiber (DF) sources on short-chain fatty acids (SCFA) production and absorption in the hindgut of growing pigs were studied by an in vivo–vitro (ileal cannulated pigs and fecal inoculum-based fermentation) method.
Hao Ye (519545), Jinbiao Zhao (5541242), Yu Bai (258833), Yu Pi (7482833), Junjun Wang (147321), Xingjian Zhou (2308483), Zhenyu Wang (580934), Dandan Han (1582408), Dongsheng Che (16704), Shuai Zhang (115662)   +9 more
core   +1 more source