Results 51 to 60 of about 63,687 (336)

Probiotic Lactobacillus reuteri DSM 17938: what is known about it today?

Медицинский совет, 2019
The review is devoted to the analysis of data on the effects of Lactobacillus reuteri DSM 17938, confirmed in clinical trials. Thanks to their antimicrobial activity, L. reuteri is able to inhibit colonization by pathogenic microorganisms and restore the
I. N. Zakharova, I. V. Berezhnaya, A. Е. Kuchina, O. V. Dedikova   +3 more
doaj   +1 more source

The Effects of Short-Chain Fatty Acids in Urological Diseases [PDF]

Urogenital Tract Infection, 2022
The gut microbiome, believed to serve as a second genome within the human body, is involved in the regulation of several metabolic processes. These include human gene expression, development, nutrition and homeostasis.
Hee Jo Yang, Doo Sang Kim
doaj   +1 more source

Gut-muscle crosstalk: The effect of endurance training and probiotic supplementation on intestinal villus structure, postbiotics and VO2max in old male rats [PDF]

Journal of Exercise & Organ Cross Talk
The aim of this study was the effect of endurance exercise and probiotic supplement enriched with amino acid leucine and vitamin D on the gut-muscle axis in aged male rats. For this purpose, 25 male Wistar rats (5 rats in each group) in two age groups of
Lotfali Lotfi, Bahman Mirzaei, Javad Mehrabani   +2 more
doaj   +1 more source

Microbiota-derived short chain fatty acids modulate microglia and promote Aβ plaque deposition

eLife, 2021
Previous studies have identified a crucial role of the gut microbiome in modifying Alzheimer’s disease (AD) progression. However, the mechanisms of microbiome–brain interaction in AD were so far unknown.
Alessio Vittorio Colombo, Rebecca Katie Sadler, Gemma Llovera, Vikramjeet Singh, Stefan Roth, Steffanie Heindl, Laura Sebastian Monasor, Aswin Verhoeven, Finn Peters, Samira Parhizkar, Frits Kamp, Mercedes Gomez de Aguero, Andrew J MacPherson, Edith Winkler, Jochen Herms, Corinne Benakis, Martin Dichgans, Harald Steiner, Martin Giera, Christian Haass, Sabina Tahirovic, Arthur Liesz   +21 more
doaj   +1 more source

Gut microbiota is correlated with gastrointestinal adverse events of metformin in patients with type 2 diabetes

Frontiers in Endocrinology, 2022
AimGastrointestinal discomfort is the most common adverse event in metformin treatment for type 2 diabetes. The mechanism of action of metformin is associated with gut microbiota.
Yuxin Huang, Xudan Lou, Cuiping Jiang, Xueying Ji, Xiaoming Tao, Jiao Sun, Zhijun Bao   +6 more
doaj   +1 more source

SCFAs Take a Toll En Route to Metabolic Syndrome [PDF]

Cell Metabolism, 2015
Gut dysbiosis is associated with development of metabolic syndrome in Tlr5(-/-) mice, but the underlying mechanism remains unclear. In this issue, Singh et al. (2015) report that augmented SCFA levels play a deleterious role in metabolic syndrome by promoting conversion of SFA to oleate in Tlr5(-/-) mice via increased liver SCD1expression.
Marette, André, Jobin, Christian
openaire   +2 more sources

GPR43 mediates microbiota metabolite SCFA regulation of antimicrobial peptide expression in intestinal epithelial cells via activation of mTOR and STAT3

Mucosal Immunology, 2018
The antimicrobial peptides (AMP) produced by intestinal epithelial cells (IEC) play crucial roles in the regulation of intestinal homeostasis by controlling microbiota.
Ye Zhao, Feidi Chen, Wei Wu, Mingming Sun, A. Bilotta, Suxia Yao, Yi Xiao, Xiangsheng Huang, T. Eaves-Pyles, G. Golovko, Y. Fofanov, Warren N D'Souza, Qihong Zhao, Zhanju Liu, Y. Cong   +14 more
semanticscholar   +1 more source

Short-chain fatty acid acetate triggers antiviral response mediated by RIG-I in cells from infants with respiratory syncytial virus bronchiolitis

EBioMedicine, 2022
Summary: Background: Gut microbiota-derived short-chain fatty-acid (SFCA) acetate protects mice against RSV A2 strain infection by increasing interferon-β production and expression of interferon-stimulated genes (ISGs).
Krist H. Antunes, Renato T. Stein, Caroline Franceschina, Emanuelle F. da Silva, Deise N. de Freitas, Josiane Silveira, Magáli Mocellin, Lidiane Leitão, José L. Fachi, Laís P. Pral, Amanda Gonzalez, Sarah Oliveira, Leonardo Duarte, Gisele Cassão, João I.B. Gonçalves, Tatiane M. Reis, Bruno L Abbadi, Maiele Dornelles, Nathália D.M. Sperotto, Maurício Rigo, Hosana Rodrigues, Marcus Jones, Matias Epifanio, Suzana Guima, João C. Setubal, Taissa R. Jorge, Daniel S. Mansur, Fabiana Q. Mayer, Ana Paula M. Varela, Cristiano V. Bizarro, Pablo Machado, Luiz A. Basso, Fernando P. Polack, Adnan Custovic, Marco A.R. Vinolo, Ana Paula D. de Souza   +35 more
doaj   +1 more source

SCFA

, 2015
SCF
Andres Gomez (169335), Ingrid Koppova (3322596), David Modry (3322593), Manolito Torralba (123370), Bryan A. White (169362), Stumpf, Rebecca M., Alexander Ulanov (430845), Brenda Wilson (2228395), Gaskins, H. Rex, H. Rex Gaskins (204198), Carbonero, Franck, Todd, Angelique, White, Bryan A., Karen Nelson (287278), Petrzelkova, Klara, Vlckova, Klara, Jakub Mrázek (3322587), Yeoman, Carl J., Franck Carbonero (206021), Modry, David, Gomez, Andres, Klara Vlckova (3322584), Steven R. Leigh (237563), Rebecca M. Stumpf (237560), Koppova, Ingrid, Nelson, Karen, Angelique Todd (112930), Carl J. Yeoman (169344), Ulanov, Alexander, Klara Petrzelkova (3322590), Torralba, Manolito, Mrázek, Jakub, Leigh, Steven R., Wilson, Brenda   +33 more
core   +1 more source

Short chain fatty acids and monocarboxylate transporters in irritable bowel syndrome

The Turkish Journal of Gastroenterology, 2020
Background/Aims: Gut microbiota ferments indigestible food that rests in the colon to produce short-chain fatty acids (SCFAs) acetate, propionate, and butyrate.
Ernst Fredericks, Reza Theunissen, Saartjie Roux   +2 more
doaj   +1 more source