Results 51 to 60 of about 58,221 (301)

Short chain fatty acids and monocarboxylate transporters in irritable bowel syndrome

The Turkish Journal of Gastroenterology, 2020
Background/Aims: Gut microbiota ferments indigestible food that rests in the colon to produce short-chain fatty acids (SCFAs) acetate, propionate, and butyrate.
Ernst Fredericks, Reza Theunissen, Saartjie Roux   +2 more
doaj   +1 more source

Gut-muscle crosstalk: The effect of endurance training and probiotic supplementation on intestinal villus structure, postbiotics and VO2max in old male rats [PDF]

Journal of Exercise & Organ Cross Talk
The aim of this study was the effect of endurance exercise and probiotic supplement enriched with amino acid leucine and vitamin D on the gut-muscle axis in aged male rats. For this purpose, 25 male Wistar rats (5 rats in each group) in two age groups of
Lotfali Lotfi, Bahman Mirzaei, Javad Mehrabani   +2 more
doaj   +1 more source

Modulating the Gut–Muscle Axis: Increasing SCFA-Producing Gut Microbiota Commensals and Decreasing Endotoxin Production to Mitigate Cancer Cachexia

Microorganisms
Cancer cachexia is a multi-organ and multifactorial syndrome characterized by muscle wasting (with or without adipose tissue loss) and systemic inflammation in patients with advanced malignancies.
Sagnik Roy, A. H. Alizadeh Bahmani, M. Davids, H. Herrema, M. Nieuwdorp   +4 more
semanticscholar   +1 more source

Short Chain Fatty Acids Modulate the Growth and Virulence of Pathosymbiont Escherichia coli and Host Response

Antibiotics, 2020
Short chain fatty acids (SCFA), principally acetate, propionate, and butyrate, are produced by fermentation of dietary fibers by the gut microbiota. SCFA regulate the growth and virulence of enteric pathogens, such as enterohemorrhagic E.
Shiying Zhang, Belgin Dogan, Cindy Guo, Deepali Herlekar, Katrina Stewart, Ellen J. Scherl, Kenneth W. Simpson   +6 more
doaj   +1 more source

Short-chain fatty acids (SCFA) in infants’ plasma and corresponding mother’s milk and plasma in relation to subsequent sensitisation and atopic disease

EBioMedicine
Summary Background Short-chain fatty acids (SCFAs) in intestinal contents may influence immune function, while less is known about SCFAs in blood plasma.
M. Barman, Monica Gio-Batta, Léna Andrieux, Mia Stråvik, R. Saalman, Rikard Fristedt, H. Rabe, Anna Sandin, Agnes E. Wold, A. Sandberg   +9 more
semanticscholar   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Impact of the source of fermentable carbohydrate on SCFA production by human gut microbiota in vitro - a systematic scoping review and secondary analysis

Critical reviews in food science and nutrition, 2020
Short chain fatty acids (SCFA) are produced by bacterial fermentation of non-digestible carbohydrates (NDC) and have many potential tissue and SCFA specific actions, from providing fuel for colonic cells to appetite regulation.
H. Harris, D. Morrison, C. Edwards
semanticscholar   +1 more source

Do SCFA have a role in appetite regulation? [PDF]

Proceedings of the Nutrition Society, 2011
The recently discovered SCFA-activated G-coupled protein receptors FFA receptor 2 and FFA receptor 3 are co-localised inl-cells with the anorexigenic ‘ileal brake’ gut hormone peptide YY, and also in adipocytes, with activation stimulating leptin release.
Darzi, J, Frost, GS, Robertson, MD
openaire   +4 more sources

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Distinct fecal and oral microbiota composition in human type 1 diabetes, an observational study. [PDF]

PLoS ONE, 2017
Environmental factors driving the development of type 1 diabetes (T1D) are still largely unknown. Both animal and human studies have shown an association between altered fecal microbiota composition, impaired production of short-chain fatty acids (SCFA ...
Pieter F de Groot, Clara Belzer, Ömrüm Aydin, Evgeni Levin, Johannes H Levels, Steven Aalvink, Fransje Boot, Frits Holleman, Daniël H van Raalte, Torsten P Scheithauer, Suat Simsek, Frank G Schaap, Steven W M Olde Damink, Bart O Roep, Joost B Hoekstra, Willem M de Vos, Max Nieuwdorp   +16 more
doaj   +1 more source