Results 31 to 40 of about 58,221 (301)

Fecal microbiota transplantation enhances cell therapy in a rat model of hypoganglionosis by SCFA‐induced MEK1/2 signaling pathway

EMBO Journal, 2022
Hirschsprung disease (HSCR), one of several neurocristopathies in children, is characterized by nerve loss in the large intestine and is mainly treated by surgery, which causes severe complications.
Donghao Tian, Wenyao Xu, Weikang Pan, Baijun Zheng, Weili Yang, Wanying Jia, Yong Liu, M. Garstka, Ya Gao, Hui Yu   +9 more
semanticscholar   +1 more source

The influence of orally administered short chain fatty acids on intestinal histopathological changes and intensity of Trichinella spiralis infection in mice

Veterinární Medicína, 2010
The influence of short chain fatty acids (SCFA) on histopathological changes in the small intestine and the intensity of invasion of T. spiralis in mice were investigated in this study. The animals were infected with doses of 500 and 250 T.
D. Mista, J. Piekarska, M. Houszka, W. Zawadzki, M. Gorczykowski   +4 more
doaj   +1 more source

Gut microbiota-derived short chain fatty acids are potential mediators in gut inflammation

Animal Nutrition, 2022
Gut inflammation is a challenging concern in humans and animals, which disturbs normal growth and leads to severe bowel diseases. Short chain fatty acids (SCFA) are the gut microbiota metabolites produced from fermentation of non-digestible carbohydrates,
Muhammad Akhtar, Yan Chen, Ziyu Ma, Xiaolong Zhang, Deshi Shi, Jawaria A. Khan, Huazhen Liu   +6 more
doaj   +1 more source

SCFA Treatment Alleviates Pathological Signs of Migraine and Related Intestinal Alterations in a Mouse Model of NTG-Induced Migraine

Cells, 2021
Background: There is a growing realization that the gut–brain axis signaling is critical for maintaining the health and homeostasis of the Central Nervous System (CNS) and the intestinal environment.
M. Lanza, A. Filippone, Alessio Ardizzone, Giovanna Casili, I. Paterniti, E. Esposito, M. Campolo   +6 more
semanticscholar   +1 more source

Noninvasive monitoring of fibre fermentation in healthy volunteers by analyzing breath volatile metabolites: lessons from the FiberTAG intervention study

Gut Microbes, 2021
The fermentation of dietary fibre (DF) leads to the production of bioactive metabolites, the most volatile ones being excreted in the breath.
Audrey M. Neyrinck, Julie Rodriguez, Zhengxiao Zhang, Benjamin Seethaler, Florence Mailleux, Joeri Vercammen, Laure B. Bindels, Patrice D. Cani, Julie-Anne Nazare, Véronique Maquet, Martine Laville, Stephan C. Bischoff, Jens Walter, Nathalie M. Delzenne   +13 more
doaj   +1 more source

Implications of SCFAs on the Parameters of the Lipid and Hepatic Profile in Pregnant Women [PDF]

Nutrients, 2021
Short-chain fatty acids (SCFAs) are the product of the anaerobic intestinal bacterial fermentation of dietary fiber and resistant starch. An abnormal intestinal microbiota may cause a reduction in the production of SCFAs, which stimulate the development of intestinal epithelial cells, nourish enterocytes, influence their maturation and proper ...
Maciej Ziętek, Zbigniew Celewicz, Justyna Kikut, Małgorzata Szczuko   +3 more
openaire   +2 more sources

Dietary betaine prevents obesity through gut microbiota-drived microRNA-378a family

Gut Microbes, 2021
Betaine is a natural compound present in commonly consumed foods and may have a potential role in the regulation of glucose and lipids metabolism. However, the underlying molecular mechanism of its action remains largely unknown.
Jingjing Du, Peiwen Zhang, Jiang Luo, Linyuan Shen, Shunhua Zhang, Hao Gu, Jin He, Linghui Wang, Xue Zhao, Mailing Gan, Liu Yang, Lili Niu, Ye Zhao, Qianzi Tang, Guoqing Tang, Dongmei Jiang, Yanzhi Jiang, Mingzhou Li, Anan Jiang, Long Jin, Jideng Ma, Surong Shuai, Lin Bai, Jinyong Wang, Bo Zeng, De Wu, Xuewei Li, Li Zhu   +27 more
doaj   +1 more source

Early life administration of milk fat globule membrane promoted SCFA-producing bacteria colonization, intestinal barriers and growth performance of neonatal piglets

Animal Nutrition, 2021
Milk fat globule membrane (MFGM) possesses various nutritional and biological benefits for mammals, whereas its effects on neonatal gut microbiota and barrier integrity remained unclear.
Yujun Wu, Xiangyu Zhang, Dandan Han, Y. Pi, S. Tao, Shiyi Zhang, Shilan Wang, Junying Zhao, Lijun Chen, Junjun Wang   +9 more
semanticscholar   +1 more source

SCFA transport in rat duodenum

American Journal of Physiology-Gastrointestinal and Liver Physiology, 2015
Bacterial or ingested food-derived short-chain fatty acids (SCFAs) are present in the duodenal lumen. Acetate, the most abundant SCFA in the foregut lumen, is absorbed immediately after ingestion, although the mechanism by which this absorption occurs is not fully understood. We investigated the distribution and function of candidate SCFA transporters
Izumi, Kaji, Toshihiko, Iwanaga, Masahiko, Watanabe, Paul H, Guth, Eli, Engel, Jonathan D, Kaunitz, Yasutada, Akiba   +6 more
openaire   +3 more sources

Low-Dose Interleukin-2 Altered Gut Microbiota and Ameliorated Collagen-Induced Arthritis

Journal of Inflammation Research, 2022
Na Li,1 Xuefei Li,1 Rui Su,1 Ruihe Wu,1 Hong-Qing Niu,1 Jing Luo,1 Chong Gao,2 Xiaofeng Li,1 Caihong Wang1 1Department of Rheumatology, The Second Hospital of Shanxi Medical University, Taiyuan, Shanxi, People’s Republic of China; 2Pathology, Joint ...
Li N, Li X, Su R, Wu R, Niu HQ, Luo J, Gao C, Li X, Wang C   +8 more
doaj