Results 31 to 40 of about 51,375 (256)

Gut microbiota is correlated with gastrointestinal adverse events of metformin in patients with type 2 diabetes

Frontiers in Endocrinology, 2022
AimGastrointestinal discomfort is the most common adverse event in metformin treatment for type 2 diabetes. The mechanism of action of metformin is associated with gut microbiota.
Yuxin Huang, Xudan Lou, Cuiping Jiang, Xueying Ji, Xiaoming Tao, Jiao Sun, Zhijun Bao   +6 more
doaj   +1 more source

Microbiota-derived short chain fatty acids modulate microglia and promote Aβ plaque deposition

eLife, 2021
Previous studies have identified a crucial role of the gut microbiome in modifying Alzheimer’s disease (AD) progression. However, the mechanisms of microbiome–brain interaction in AD were so far unknown.
Alessio Vittorio Colombo, Rebecca Katie Sadler, Gemma Llovera, Vikramjeet Singh, Stefan Roth, Steffanie Heindl, Laura Sebastian Monasor, Aswin Verhoeven, Finn Peters, Samira Parhizkar, Frits Kamp, Mercedes Gomez de Aguero, Andrew J MacPherson, Edith Winkler, Jochen Herms, Corinne Benakis, Martin Dichgans, Harald Steiner, Martin Giera, Christian Haass, Sabina Tahirovic, Arthur Liesz   +21 more
doaj   +1 more source

SCFA

, 2015
SCF
Andres Gomez (169335), Ingrid Koppova (3322596), David Modry (3322593), Manolito Torralba (123370), Bryan A. White (169362), Stumpf, Rebecca M., Alexander Ulanov (430845), Brenda Wilson (2228395), Gaskins, H. Rex, H. Rex Gaskins (204198), Carbonero, Franck, Todd, Angelique, White, Bryan A., Karen Nelson (287278), Petrzelkova, Klara, Vlckova, Klara, Jakub Mrázek (3322587), Yeoman, Carl J., Franck Carbonero (206021), Modry, David, Gomez, Andres, Klara Vlckova (3322584), Steven R. Leigh (237563), Rebecca M. Stumpf (237560), Koppova, Ingrid, Nelson, Karen, Angelique Todd (112930), Carl J. Yeoman (169344), Ulanov, Alexander, Klara Petrzelkova (3322590), Torralba, Manolito, Mrázek, Jakub, Leigh, Steven R., Wilson, Brenda   +33 more
core   +1 more source

Short chain fatty acids and monocarboxylate transporters in irritable bowel syndrome

The Turkish Journal of Gastroenterology, 2020
Background/Aims: Gut microbiota ferments indigestible food that rests in the colon to produce short-chain fatty acids (SCFAs) acetate, propionate, and butyrate.
Ernst Fredericks, Reza Theunissen, Saartjie Roux   +2 more
doaj   +1 more source

Short-chain fatty acid acetate triggers antiviral response mediated by RIG-I in cells from infants with respiratory syncytial virus bronchiolitis

EBioMedicine, 2022
Summary: Background: Gut microbiota-derived short-chain fatty-acid (SFCA) acetate protects mice against RSV A2 strain infection by increasing interferon-β production and expression of interferon-stimulated genes (ISGs).
Krist H. Antunes, Renato T. Stein, Caroline Franceschina, Emanuelle F. da Silva, Deise N. de Freitas, Josiane Silveira, Magáli Mocellin, Lidiane Leitão, José L. Fachi, Laís P. Pral, Amanda Gonzalez, Sarah Oliveira, Leonardo Duarte, Gisele Cassão, João I.B. Gonçalves, Tatiane M. Reis, Bruno L Abbadi, Maiele Dornelles, Nathália D.M. Sperotto, Maurício Rigo, Hosana Rodrigues, Marcus Jones, Matias Epifanio, Suzana Guima, João C. Setubal, Taissa R. Jorge, Daniel S. Mansur, Fabiana Q. Mayer, Ana Paula M. Varela, Cristiano V. Bizarro, Pablo Machado, Luiz A. Basso, Fernando P. Polack, Adnan Custovic, Marco A.R. Vinolo, Ana Paula D. de Souza   +35 more
doaj   +1 more source

Fecal SCFA concentrations and proportion of total SCFA content in rats.

, 2014
(A) Fecal acetic acid concentration and percentage as total SCFA content. (B) Fecal propionic acid concentration and percentage of total SCFA content. (C) Fecal isobutyric acid concentration and percentage of total SCFA content.
Yonghua Yang (374048), Mingming Zhang (362844), Chenggong Yu (49442), Xiaotong Yang (638629), Hui Chen (28597), Na Hong (638630), Xinyun Qiu (638628), Hao Zhang (15339)   +7 more
core   +1 more source

Gut-muscle crosstalk: The effect of endurance training and probiotic supplementation on intestinal villus structure, postbiotics and VO2max in old male rats [PDF]

Journal of Exercise & Organ Cross Talk
The aim of this study was the effect of endurance exercise and probiotic supplement enriched with amino acid leucine and vitamin D on the gut-muscle axis in aged male rats. For this purpose, 25 male Wistar rats (5 rats in each group) in two age groups of
Lotfali Lotfi, Bahman Mirzaei, Javad Mehrabani   +2 more
doaj   +1 more source

Short Chain Fatty Acids Modulate the Growth and Virulence of Pathosymbiont Escherichia coli and Host Response

Antibiotics, 2020
Short chain fatty acids (SCFA), principally acetate, propionate, and butyrate, are produced by fermentation of dietary fibers by the gut microbiota. SCFA regulate the growth and virulence of enteric pathogens, such as enterohemorrhagic E.
Shiying Zhang, Belgin Dogan, Cindy Guo, Deepali Herlekar, Katrina Stewart, Ellen J. Scherl, Kenneth W. Simpson   +6 more
doaj   +1 more source

Relationship Between Short Chain Fatty Acids and Menarche in Elementary School Students in Padang City

Andalas Obstetrics and Gynecology Journal
Introduction: Early menarche is associated with long-term health problems. Currently, adolescent girls are increasingly experience the change of menarche age.
Zulfiqar MS, Haviz Yuad, Husna Yetti, Defrin Defrin, Ferdinal Ferry, Mondale Saputra   +5 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source