Results 11 to 20 of about 58,221 (301)

SCFA: mechanisms and functional importance in the gut [PDF]

Proceedings of the Nutrition Society, 2020
In recent years, the importance of the gut microbiota in human health has been revealed and many publications have highlighted its role as a key component of human physiology.
C. Martin-Gallausiaux, L. Marinelli, H. Blottière, P. Larraufie, N. Lapaque   +4 more
semanticscholar   +3 more sources

Fecal SCFAs and SCFA-producing bacteria in gut microbiome of human NAFLD as a putative link to systemic T-cell activation and advanced disease [PDF]

United European Gastroenterology Journal, 2018
Background Intestinal microbiota and their metabolites (e.g. short-chain fatty acids (SCFAs)) may influence nonalcoholic fatty liver disease (NAFLD). Objective The objective of this article is to analyze gut bacterial diversity together with fecal SCFA ...
M. Rau, A. Rehman, M. Dittrich, A. Groen, H. Hermanns, F. Seyfried, N. Beyersdorf, T. Dandekar, P. Rosenstiel, A. Geier   +9 more
semanticscholar   +4 more sources

Microbiota and SCFA in Lean and Overweight Healthy Subjects [PDF]

Obesity, 2010
Obesity has recently been linked to the composition of human microbiota and the production of short chain fatty acids (SCFAs). However, these findings rely on experimental studies carried out using rather small and defined groups of volunteers or model animals.
A. Schwiertz, D. Taras, K. Schäfer, S. Beijer, N. Bos, Christiane Donus, P. Hardt   +6 more
semanticscholar   +4 more sources

Combined effect of microbially derived cecal SCFA and host genetics on feed efficiency in broiler chickens

Microbiome, 2023
Background Improving feed efficiency is the most important goal for modern animal production. The regulatory mechanisms of controlling feed efficiency traits are extremely complex and include the functions related to host genetics and gut microbiota ...
Zhengxiao He, Ranran Liu, Mengjie Wang, Qiao Wang, Jumei Zheng, Jiqiang Ding, J. Wen, A. Fahey, Guiping Zhao   +8 more
semanticscholar   +1 more source

Polysaccharides from Tetrastigma Hemsleyanum Diels et Gilg ameliorated inflammatory bowel disease by rebuilding the intestinal mucosal barrier and inhibiting inflammation through the SCFA-GPR41/43 signaling pathway.

International Journal of Biological Macromolecules, 2023
In this study, the therapeutic effects of Tetrastigma hemsleyanum polysaccharide (THP) on inflammatory bowel disease (IBD) and its possible mechanisms were investigated based on the IBD mouse model induced by dextran sodium sulfate (DSS) and the ...
Yue Lin, Yishan Lv, Zi'an Mao, Xingcan Chen, Yuchi Chen, Bingqi Zhu, Yi Yu, Zhishan Ding, Fangmei Zhou   +8 more
semanticscholar   +1 more source

Genetic and gut microbiome determinants of SCFA circulating and fecal levels, postprandial responses and links to chronic and acute inflammation

Gut microbes, 2023
Short-chain fatty acids (SCFA) are involved in immune system and inflammatory responses. We comprehensively assessed the host genetic and gut microbial contribution to a panel of eight serum and stool SCFAs in two cohorts (TwinsUK, n = 2507; ZOE PREDICT ...
A. Nogal, F. Asnicar, Amrita Vijay, Afroditi Kouraki, A. Visconti, P. Louca, Kari E. Wong, A. Baleanu, Francesca Giordano, J. Wolf, G. Hadjigeorgiou, R. Davies, G. Michelotti, P. Franks, S. Berry, M. Falchi, A. Ikram, B. Ollivere, Amy Zheng, J. Nightingale, M. Mangino, N. Segata, W. Bulsiewicz, T. Spector, A. Valdes, C. Menni   +25 more
semanticscholar   +1 more source

Commensal microbe-derived SCFA alleviates atrial fibrillation via GPR43/NLRP3 signaling

International Journal on Biological Sciences, 2022
Rationale: Dysbiotic gut microbiota (GM) and NLRP3 inflammasome are proarrhythmic factors in atrial fibrillation (AF). Herein, whether short-chain fatty acid (SCFA) produced from GM fermentation of dietary fiber serving as invisible mediators is yet ...
K. Zuo, Chen Fang, Zheng Liu, Yuan Fu, Ye Liu, Lifeng Liu, Yuxing Wang, X. Yin, Xiaoqing Liu, Jing Li, Jiuchang Zhong, Mulei Chen, Li Xu, Xinchun Yang   +13 more
semanticscholar   +1 more source

The Impact of Migration on the Gut Metagenome of South Asian Canadians

Gut Microbes, 2021
South Asian (SA) Canadian immigrants have a higher risk of developing certain immune-mediated inflammatory diseases compared to non-migrant SAs. We sought to investigate the effect of migration on the gut metagenome and to identify microbiological ...
Julia K. Copeland, Gary Chao, Shelley Vanderhout, Erica Acton, Pauline W. Wang, Eric I. Benchimol, Ahmed El-Sohemy, Ken Croitoru, Jennifer L. Gommerman, David S. Guttman, the GEMINI Research Team   +10 more
doaj   +1 more source

Bekatul Beras Hitam Terfermentasi Memperbaiki Kondisi Kolon Mencit yang Diinduksi Senyawa Karsinogen Azoxymethane

Jurnal Teknologi dan Industri Pangan, 2023
Worldwide, colon cancer has become the fourth cause of death in terms of cancer. A high fiber and antioxidants diet help promote a healthy diet and prevent colon cancer. Black rice bran has high content both in fiber and phenolic.
Nouverra Nadya Putri, Slamet Budijanto, Endang Prangdimurti, Bambang Pontjo   +3 more
doaj   +1 more source

Fecal levels of SCFA and BCFA during capecitabine in patients with metastatic or unresectable colorectal cancer

Clinical and Experimental Medicine (Testo stampato), 2023
Gut bacteria-derived short-chain fatty acids (SCFA) and branched-chain fatty acids (BCFA) are considered to have beneficial metabolic, anti-inflammatory as well as anti-carcinogenic effects.
J. Ziemons, R. Aarnoutse, Anne Heuft, L. Hillege, J. Waelen, J. de Vos-Geelen, L. V. Valkenburg-van Iersel, Irene E. G. van Hellemond, G. Creemers, A. Baars, J. Vestjens, J. Penders, Koen Venema, M. Smidt   +13 more
semanticscholar   +1 more source