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The Therapeutic Effect of SCFA-Mediated Regulation of the Intestinal Environment on Obesity

open access: yesFrontiers in Nutrition, 2022
Intestinal environment disorder is a potential pathological mechanism of obesity. There is increasing evidence that disorders in the homeostasis of the intestinal environment can affect various metabolic organs, such as fat and liver, and lead to ...
Wei-ai Zhang
exaly   +3 more sources

SCFA biotherapy delays diabetes in humanized gnotobiotic mice by remodeling mucosal homeostasis and metabolome

open access: yesNature Communications
Type 1 diabetes (T1D) is linked to an altered gut microbiota characterized by reduced short-chain fatty acid (SCFA) production. Oral delivery of a SCFA-yielding biotherapy in adults with T1D was followed by increased SCFAs, altered gut microbiota and ...
Sonia Saad   +2 more
exaly   +2 more sources

Production of Organic Acid and Short-Chain Fatty Acids (SCFA) from Lactic Acid Bacteria Isolate on Oligosaccharide Media

open access: yesJurnal Kimia Sains dan Aplikasi, 2021
The growth of microorganisms in food, one of which is lactic acid bacteria (LAB), can produce metabolites beneficial to health. It is essential to study the results of LAB metabolism to improve the quality of a functional food product.
Yati Maryati   +2 more
doaj   +1 more source

Pilot study on gut microbiota profile in Indian children with type 1 diabetes

open access: yesIndian Journal of Endocrinology and Metabolism, 2023
Background: Non-genetic factors like microbial dysbiosis may be contributing to the increasing incidence/progression of type 1 diabetes mellitus (T1DM).
Nikhil Shah   +11 more
doaj   +1 more source

Nourishing Immunity and Combatting Neuroinflammation: The Power of Immunonutrition and The Microbiome

open access: yesFrontiers in Bioscience-Landmark, 2023
The gut-microbiome-brain axis plays a crucial role in the control of systemic metabolism and homeostasis. Recent research has shown that dietary habits and nutrients can affect immune system and inflammatory status by influencing various factors ...
Eda Nur Dübüş   +3 more
doaj   +1 more source

The Impact of Migration on the Gut Metagenome of South Asian Canadians

open access: yesGut Microbes, 2021
South Asian (SA) Canadian immigrants have a higher risk of developing certain immune-mediated inflammatory diseases compared to non-migrant SAs. We sought to investigate the effect of migration on the gut metagenome and to identify microbiological ...
Julia K. Copeland   +10 more
doaj   +1 more source

IRON-FORTIFIED SYNBIOTIC FERMENTED MILK WITH TEMPEH EXTRACT TO ENHANCES PROPIONIC ACID, BUTYRIC ACID, AND NON-PATHOGEN MICROBIOME IN ANEMIC WISTAR RAT

open access: yesMedia Gizi Mikro Indonesia, 2020
Background. Anemia, as a global public health problem, needs to be solved. The previous study by the researcher found the potency of iron-fortified synbiotic fermented milk with tempeh extract as an alternative to overcome anemia. Objective.
Mohammad Juffrie, Siti Helmyati
doaj   +1 more source

The anti-inflammatory effect of bacterial short chain fatty acids is partially mediated by endocannabinoids

open access: yesGut Microbes, 2021
The endocannabinoid (EC) system has pleiotropic functions in the body. It plays a key role in energy homeostasis and the development of metabolic disorders being a mediator in the relationship between the gut microbiota and host metabolism.
Amrita Vijay   +8 more
doaj   +1 more source

Research Progress on the Functions of Short Chain Fatty Acid [PDF]

open access: yesShipin Kexue, 2023
Short chain fatty acid (SCFA), a class of fatty acids with six or less carbon atoms, have important physiological functions for human health. As metabolites of the intestinal flora, SCFA can maintain intestinal health.
YANG Xue, GAO Yanan, WANG Jiaqi, ZHENG Nan
doaj   +1 more source

Gut Microbial Protein Expression in Response to Dietary Patterns in a Controlled Feeding Study: A Metaproteomic Approach

open access: yesMicroorganisms, 2020
Although the gut microbiome has been associated with dietary patterns linked to health, microbial metabolism is not well characterized. This ancillary study was a proof of principle analysis for a novel application of metaproteomics to study microbial ...
Sheng Pan   +11 more
doaj   +1 more source

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