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The Therapeutic Effect of SCFA-Mediated Regulation of the Intestinal Environment on Obesity
Frontiers in Nutrition, 2022 Intestinal environment disorder is a potential pathological mechanism of obesity. There is increasing evidence that disorders in the homeostasis of the intestinal environment can affect various metabolic organs, such as fat and liver, and lead to ...
Jincan He, Hua Cao, Qishi Che
exaly +6 more sources
The Associations of SCFA with Anthropometric Parameters and Carbohydrate Metabolism in Pregnant Women [PDF]
International Journal of Molecular Sciences, 2020 Short-chain fatty acids (SCFAs) mediate the transmission of signals between the microbiome and the immune system and are responsible for maintaining balance in the anti-inflammatory reaction. Pregnancy stages alter the gut microbiota community structure, which also synthesizes SCFAs.
Małgorzata Szczuko +2 more
exaly +4 more sources
Fecal SCFAs and SCFA‐producing bacteria in gut microbiome of human NAFLD as a putative link to systemic T‐cell activation and advanced disease [PDF]
United European Gastroenterology Journal, 2018 BackgroundIntestinal microbiota and their metabolites (e.g. short‐chain fatty acids (SCFAs)) may influence nonalcoholic fatty liver disease (NAFLD).ObjectiveThe objective of this article is to analyze gut bacterial diversity together with fecal SCFA concentrations and immunophenotyping of peripheral blood in histology‐proven NAFLD patients ...
Monika Rau +2 more
exaly +5 more sources
SCFA: mechanisms and functional importance in the gut [PDF]
Proceedings of the Nutrition Society, 2020 In recent years, the importance of the gut microbiota in human health has been revealed and many publications have highlighted its role as a key component of human physiology. Owing to the use of modern sequencing approaches, the characterisation of the microbiome in healthy individuals and in disease has demonstrated a disturbance of the microbiota ...
Camille Martin-Gallausiaux +4 more
openaire +3 more sources
Methanol-driven esterification of volatile short-chain fatty acids in thermal desorption-based analysis [PDF]
Communications ChemistryBreath volatile organic compound analysis can non-invasively detect diseases, with short-chain fatty acids (SCFAs) identified as key biomarkers. However, SCFA quantification is technically challenging due to chemical instability during thermal desorption
Philip Kwan Hung Leung +9 more
doaj +2 more sources
Jurnal Kimia Sains dan Aplikasi, 2021 The growth of microorganisms in food, one of which is lactic acid bacteria (LAB), can produce metabolites beneficial to health. It is essential to study the results of LAB metabolism to improve the quality of a functional food product.
Yati Maryati +2 more
doaj +1 more source
Pilot study on gut microbiota profile in Indian children with type 1 diabetes
Indian Journal of Endocrinology and Metabolism, 2023 Background: Non-genetic factors like microbial dysbiosis may be contributing to the increasing incidence/progression of type 1 diabetes mellitus (T1DM).
Nikhil Shah +11 more
doaj +1 more source
Frontiers in Bioscience-Landmark, 2023 The gut-microbiome-brain axis plays a crucial role in the control of systemic metabolism and homeostasis. Recent research has shown that dietary habits and nutrients can affect immune system and inflammatory status by influencing various factors ...
Eda Nur Dübüş +3 more
doaj +1 more source
The SCFA Receptor GPR43 and Energy Metabolism [PDF]
Frontiers in Endocrinology, 2014 Free fatty acids (FFAs) are essential nutrients and act as signaling molecules in various cellular processes via binding with FFA receptors. Of these receptors, GPR43 is activated by short-chain fatty acids (SCFAs; e.g., acetate, propionate, and butyrate).
Ikuo eKimura +4 more
openaire +3 more sources
The Impact of Migration on the Gut Metagenome of South Asian Canadians
Gut Microbes, 2021 South Asian (SA) Canadian immigrants have a higher risk of developing certain immune-mediated inflammatory diseases compared to non-migrant SAs. We sought to investigate the effect of migration on the gut metagenome and to identify microbiological ...
Julia K. Copeland +10 more
doaj +1 more source