Results 131 to 140 of about 275,856 (278)
Optimal schedules for annealing algorithms
Physical Review EAnnealing algorithms such as simulated annealing and population annealing are widely used both for sampling the Gibbs distribution and solving optimization problems (i.e. finding ground states). For both statistical mechanics and optimization, additional parameters beyond temperature are often needed such as chemical potentials, external fields or ...
Amin Barzegar +3 more
openaire +3 more sources
Targeting p38α in cancer: challenges, opportunities, and emerging strategies
Molecular Oncology, EarlyView.p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley +1 more source
Results in EngineeringThe optimal scheduling method of the power grid considering the node coupling degree and the duality of mutual inverse mapping is studied to effectively establish the random dynamic scene of the power grid and improve its optimal scheduling effect ...
Yunhui Wang +4 more
doaj +1 more source
Polynomial optimization techniques for activity scheduling. Optimization based prototype scheduler [PDF]
Polynomial optimization techniques for activity scheduling (optimization based prototype scheduler) are presented in the form of the viewgraphs. The following subject areas are covered: agenda; need and viability of polynomial time techniques for SNC ...
Reddy, Surender
core +1 more source
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Bi-objective bus scheduling optimization with passenger perception in mind. [PDF]
Sci Rep, 2023 Liu S, Liu L, Pei D, Wang J.
europepmc +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Order scheduling optimization in manufacturing enterprises based on MDP and dynamic programming. [PDF]
Sci Rep, 2023 Wulan Q.
europepmc +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Modeling and Optimization of Cable Production Scheduling by Incorporating an Ant Colony Algorithm
MathematicsWith the development of small batch and multi-batch service production mode, manual scheduling by hand has been difficult to adapt to the production of a large number of complex orders. This work proposed a cable production scheduling optimization method
Changbiao Zhu +4 more
doaj +1 more source