Results 91 to 100 of about 1,782,050 (353)
Molecular Oncology, EarlyView.Small extracellular vesicles are a promising source of diagnostic molecules. We conducted a comprehensive study, including transcriptome profiling and RT‐qPCR validation on large cohorts of samples. Diagnostic panels enabling sensitive detection of colorectal cancer and precancerous lesions were established. Some molecules were differentially expressed
Petra Vychytilova‐Faltejskova +26 more
wiley +1 more source
Planning and Scheduling of Business Processes in Run-Time: A Repair Planning Example [PDF]
, 2010 Over the last decade, the efficient and flexible management of business processes has become one of the most critical success aspects. Furthermore, there exists a growing interest in the application of Artificial Intelligence Planning and Scheduling ...
Barba Rodríguez, Irene +1 more
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Multi-objective decision making and search space for the evaluation of production process scheduling [PDF]
, 2009 Tadeusz Witkowski +2 more
openalex +1 more source
Molecular Oncology, EarlyView.Stemness properties, including quiescence, self‐renewal, and chemoresistance, are closely associated with leukemia relapse. Here, we demonstrate that DNA damage‐inducible transcript 4 (DDIT4) is induced in the hypoxic bone marrow niche and is essential for maintaining the stemness of AML1‐ETO9a leukemia cells.
Yishuang Li +12 more
wiley +1 more source
Development and characterization of treated kaolin filled polypropylene/kaolin nanocomposites [PDF]
, 2018 This research work focused on producing modified kaolin filler in polypropylene/kaolin (PP/K) nanocomposite by melt compounding process in order to improve its mechanical and thermal properties for industrial applications.
Yahaya, Shehu
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Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
Theory of constraints (TOC) production and manufacturing performance [PDF]
, 2016 This paper is based on an empirical study of the relationship between Theory of Constraints (TOC) production and operational performance in manufacturing plants.
Panizzolo, Roberto
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Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
Enabling Adaptive Grid Scheduling and Resource Management [PDF]
, 2005 Wider adoption of the Grid concept has led to an increasing amount of federated computational, storage and visualisation resources being available to scientists and researchers.
Lazarevic, A., Prnjat, O., Sacks, L.
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A hybrid general lot-sizing and scheduling formulation for a production process with a two-stage product structure [PDF]
, 2011 Sandra Transchel +4 more
openalex +1 more source