Results 91 to 100 of about 1,844,217 (391)
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Simulation scheduling in food industry application
Czech Journal of Food Sciences, 2002 Nowadays manufacturers are facing rapid and fundamental changes in the ways business is done. Producers are looking for simulation systems increasing throughput and profit, reducing cycle time, improving due-date performance, reducing WIP, providing ...
S. Simeonov, J. Simeonovová
doaj +1 more source
Planning and Scheduling of Business Processes in Run-Time: A Repair Planning Example [PDF]
, 2010 Over the last decade, the efficient and flexible management of business processes has become one of the most critical success aspects. Furthermore, there exists a growing interest in the application of Artificial Intelligence Planning and Scheduling ...
Barba Rodríguez, Irene +1 more
core
B2C Mass Customization in the Classroom [PDF]
, 2012 The purpose of this article is to describe an internet-based mass customization assignment in Operations Management/Supply Chain Management classes where students utilize the Web site of a company that offers a customized product.
Gu, Qiannong +2 more
core +2 more sources
Production scheduling in the process industry [PDF]
, 2013 The purpose of this paper is to formulate an optimization model for the production scheduling problem at continuous production sites. The production scheduling activity should produce a monthly schedule that accounts for orders and forecasts of all products.
Lindholm, Anna +5 more
openaire +1 more source
FEBS Letters, EarlyView.Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
Configuration of robust manufacturing systems [PDF]
, 2013 Considering the increasing turbulence in the markets, many companies are faced with the task of responding to changes in customer demand in a flexible and timely manner.
Heinicke, Matthias
core
Reengineering Production Systems: the Royal Netherlands Naval Dockyard [PDF]
, 1996 Reengineering production systems in an attempt to meet tight cost, quality and leadtime standards has received considerable attention in the last decade. In this paper, we discuss the reengineering process at the Royal Netherlands Naval Dockyard.
Zijm, W.H.M.
core +3 more sources
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source