Results 111 to 120 of about 1,844,217 (391)

Scheduling Coordination in a Supply Chain Using Advance Demand Information. [PDF]

open access: yes
In an environment of mass customization where demand information can be placed in advance with sequencing orders, the question of the best use of this information arises in a supply chain.
Giard, Vincent, Mendy-Bilek, Gisèle
core  

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Co-evolutionary Genetic Algorithms for Reactive Scheduling

open access: yesJournal of Advanced Mechanical Design, Systems, and Manufacturing, 2010
Previous researches provided a reactive scheduling method using a genetic algorithm to improve disturbed production schedules, due to unexpected disruptions, such as delays of manufacturing operations.
Yoshitaka TANIMIZU   +4 more
doaj   +1 more source

The challenge of integrating non-continuous processes-milk powder plant case study [PDF]

open access: yes, 2009
The integration of non-continuous processes such as a milk powder plant present a challenge for existing process integration techniques. Current techniques are generally based on steady and continuous operation which for some industries is not the case ...
Atkins, Martin John   +2 more
core  

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Multi-Agent System Interaction in Integrated SCM\ud [PDF]

open access: yes, 2009
Coordination between organizations on strategic, tactical and operation levels leads to more effective and efficient supply chains. Supply chain management is increasing day by day in modern enterprises..
Purohit, G. N.   +2 more
core   +1 more source

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

open access: yesFEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom   +3 more
wiley   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

ÖĞRENME ETKİLİ HAZIRLIK VE TAŞIMA ZAMANLI PARALEL MAKİNELİ ÇİZELGELEME PROBLEMİ

open access: yesHavacılık ve Uzay Teknolojileri Dergisi, 2006
In studies on scheduling problems, generally setup times and removal times of jobs have been neglected or by including those into processing times solution approaches have been developed.
Tamer Eren , Ertan Güner
doaj  

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