Results 121 to 130 of about 1,844,217 (391)

An optimal-control based integrated model of supply chain [PDF]

Problems of supply chain scheduling are challenged by high complexity, combination of continuous and discrete processes, integrated production and transportation operations as well as dynamics and resulting requirements for adaptability and stability ...
Ivanov, Dmitry
core   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Development and characterization of treated kaolin filled polypropylene/kaolin nanocomposites [PDF]

, 2018
This research work focused on producing modified kaolin filler in polypropylene/kaolin (PP/K) nanocomposite by melt compounding process in order to improve its mechanical and thermal properties for industrial applications.
Yahaya, Shehu
core  

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Ladle Intelligent Re-scheduling Method in Steelmaking–Refining–Continuous Casting Production Process based on BP Neural Network Working Condition Estimation [PDF]

, 2021
Wei Liu, Xinfu Pang, Haibo Li, Liangliang Sun   +3 more
openalex   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

Integrated Production and Transportation Scheduling on Parallel Batch-Processing Machines [PDF]

, 2019
Xin Feng, Zhongyue Xu
openalex   +1 more source

Scheduling in a flexible flow shop with unrelated parallel machines and machine-dependent process stages: Trade-off between Makespan and production costs

, 2022
Ali Hasani, Seyed Mohammad Hassan Hosseini, Shib Sankar Sana   +2 more
openalex   +1 more source

Industry 4.0: Smart Scheduling

International Journal of Production Research, 2018
Smart Manufacturing and Industry 4.0 production environments integrate the physical and decisional aspects of manufacturing processes into autonomous and decentralised systems.
D. Rossit, F. Tohmé, Mariano Frutos
semanticscholar   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source