Results 141 to 150 of about 747,950 (326)

Datasets for lot sizing and scheduling problems in the fruit-based beverage production process

open access: yesData in Brief, 2021
The datasets presented here were partially used in “Formulation and MIP-heuristics for the lot sizing and scheduling problem with temporal cleanings” (Toscano, A.,  Ferreira, D., Morabito, R., Computers & Chemical Engineering) [1], in “A ...
Juan Piñeros   +3 more
doaj  

A mathematical model for simultaneous personnel shift planning and unrelated parallel machine scheduling [PDF]

open access: yesarXiv
This paper addresses a production scheduling problem derived from an industrial use case, focusing on unrelated parallel machine scheduling with the personnel availability constraint. The proposed model optimizes the production plan over a multi-period scheduling horizon, accommodating variations in personnel shift hours within each time period.
arxiv  

AN INTEGRATED OPTIMIZATION OF PRODUCTION AND PREVENTIVE MAINTENANCE SCHEDULING IN INDUSTRY 4.0 [PDF]

open access: yes
Preventive Maintenance (PM) plays an important role in maximizing machine reliability, improving production efficiency and reducing repair costs. Due to the importance of PM in manufacturing environments, it is necessary to develop an integrated model ...
Babaeimorad, Samane   +3 more
core   +1 more source

Loss of SETD2 in wild‐type VHL clear cell renal cell carcinoma sensitizes cells to STF‐62247 and leads to DNA damage, cell cycle arrest, and cell death characteristic of pyroptosis

open access: yesMolecular Oncology, EarlyView.
Vulnerability to the small molecule STF‐62247 is observed in SETD2‐inactivated VHL‐positive clear cell renal cell carcinoma (ccRCC) cells. DNA damage and loss of CDC25A leads to cell cycle arrest in S phase. Cleavage of caspase‐3 (CASP3) and gasdermin E (GSDME) suggests cell death by pyroptosis.
Mathieu Johnson, Sandra Turcotte
wiley   +1 more source

An organizational systems perspective to business process modeling in small to medium enterprises (smes) : a case of food production [PDF]

open access: yes, 2013
Taking an organizational systems perspective, this paper presents a review to business process modelling and examines the case of food manufacture in a Small to Medium Sized Enterprise (SME), which operates in Cyprus.
Dimopoulos, Christos   +1 more
core  

The CDK12–BRCA1 signaling axis mediates dinaciclib‐associated radiosensitivity through p53‐mediated cellular senescence

open access: yesMolecular Oncology, EarlyView.
Dinaciclib blocks CDK12 activity, leading to downregulation of BRCA1, and probably other proteins involved in homologous recombination, promoting nonhomologous end joining. In this scenario, the presence of ionising radiation triggers a p53‐dependent senescent response that yields increased radiosensitivity. Pan‐cyclin‐dependent‐kinase (CDK) inhibitors
Natalia García Flores   +14 more
wiley   +1 more source

The PTTG1/VASP axis promotes oral squamous cell carcinoma metastasis by modulating focal adhesion and actin filaments

open access: yesMolecular Oncology, EarlyView.
VASP was found to be overexpressed in metastatic oral squamous cell carcinoma (OSCC) tissues. Notably, PTTG1‐ and VASP‐deficient OSCC cells demonstrated suppressed metastatic properties by disrupting the interaction between the cytoskeleton and focal adhesion (FAs) in the filopodia region.
Suyeon Park   +6 more
wiley   +1 more source

A hybrid general lot-sizing and scheduling formulation for a production process with a two-stage product structure [PDF]

open access: green, 2011
Sandra Transchel   +4 more
openalex   +1 more source

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