Results 141 to 150 of about 1,844,217 (391)

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

Scheduling with Fuzzy Methods

open access: yes, 2004
Nowadays, manufacturing industries -- driven by fierce competition and rising customer requirements -- are forced to produce a broader range of individual products of rising quality at the same (or preferably lower) cost. Meeting these demands implies an
Eiden, Wolfgang Anthony
core   +1 more source

Solving the problem of scheduling the production process based on heuristic algorithms [PDF]

open access: diamond, 2022
Dagmara Łapczyńska   +3 more
openalex   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Synthesis and Stochastic Assessment of Cost-Optimal Schedules [PDF]

open access: yes, 2006
We present a novel approach to synthesize good schedules for a class of scheduling problems that is slightly more general than the scheduling problem FJm,a|gpr,r_j,d_j|early/tardy.
Bohnenkamp, H.C.   +5 more
core   +2 more sources

Screening for lung cancer: A systematic review of overdiagnosis and its implications

open access: yesMolecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz   +12 more
wiley   +1 more source

Enabling Adaptive Grid Scheduling and Resource Management [PDF]

open access: yes, 2005
Wider adoption of the Grid concept has led to an increasing amount of federated computational, storage and visualisation resources being available to scientists and researchers.
Lazarevic, A., Prnjat, O., Sacks, L.
core  

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