Results 141 to 150 of about 775,681 (328)

Cellular liquid biopsy provides unique chances for disease monitoring, preclinical model generation and therapy adjustment in rare salivary gland cancer patients

open access: yesMolecular Oncology, EarlyView.
We quantified and cultured circulating tumor cells (CTCs) of 62 patients with various cancer types and generated CTC‐derived tumoroid models from two salivary gland cancer patients. Cellular liquid biopsy‐derived information enabled molecular genetic assessment of systemic disease heterogeneity and functional testing for therapy selection in both ...
Nataša Stojanović Gužvić   +31 more
wiley   +1 more source

S-Graph-Based Reactive Scheduling with Unexpected Arrivals of New Orders

open access: yesMachines
Manufacturing processes are often disrupted by unexpected events, such as machine breakdowns, raw material shortages, and the arrival of new orders. Effectively managing these uncertainties is crucial for maintaining the feasibility and optimality of the
Krisztián Attila Bakon   +1 more
doaj   +1 more source

Scalable Multi-agent Reinforcement Learning for Factory-wide Dynamic Scheduling [PDF]

open access: yesarXiv
Real-time dynamic scheduling is a crucial but notoriously challenging task in modern manufacturing processes due to its high decision complexity. Recently, reinforcement learning (RL) has been gaining attention as an impactful technique to handle this challenge. However, classical RL methods typically rely on human-made dispatching rules, which are not
arxiv  

Comparative study of different approaches to solve batch process scheduling and optimisation problems [PDF]

open access: yes, 2012
Effective approaches are important to batch process scheduling problems, especially those with complex constraints. However, most research focus on improving optimisation techniques, and those concentrate on comparing their difference are inadequate ...
Huang, Wei   +3 more
core  

Genomic landscape and preclinical models of angiosarcoma

open access: yesMolecular Oncology, Volume 19, Issue 4, Page 965-983, April 2025.
Angiosarcomas are a rare and aggressive cancer with a poor prognosis for patients. The genomic landscape of angiosarcoma can be highly complex and heterogenous; however, recent studies have identified some common features especially within anatomic and molecular subgroups.
Annaleigh Benton   +3 more
wiley   +1 more source

Is the GPU Half-Empty or Half-Full? Practical Scheduling Techniques for LLMs [PDF]

open access: yesarXiv
Serving systems for Large Language Models (LLMs) improve throughput by processing several requests concurrently. However, multiplexing hardware resources between concurrent requests involves non-trivial scheduling decisions. Practical serving systems typically implement these decisions at two levels: First, a load balancer routes requests to different ...
arxiv  

Combined spatially resolved metabolomics and spatial transcriptomics reveal the mechanism of RACK1‐mediated fatty acid synthesis

open access: yesMolecular Oncology, EarlyView.
The authors analyzed the spatial distributions of gene and metabolite profiles in cervical cancer through spatial transcriptomic and spatially resolved metabolomic techniques. Pivotal genes and metabolites within these cases were then identified and validated.
Lixiu Xu   +3 more
wiley   +1 more source

Optimizing Job Shop Scheduling in the Furniture Industry: A Reinforcement Learning Approach Considering Machine Setup, Batch Variability, and Intralogistics [PDF]

open access: yesarXiv
This paper explores the potential application of Deep Reinforcement Learning in the furniture industry. To offer a broad product portfolio, most furniture manufacturers are organized as a job shop, which ultimately results in the Job Shop Scheduling Problem (JSSP).
arxiv  

Gut microbiota diversity is prognostic and associated with benefit from chemo‐immunotherapy in metastatic triple‐negative breast cancer

open access: yesMolecular Oncology, Volume 19, Issue 4, Page 1229-1243, April 2025.
We assessed the associations between the gut microbiota and outcome in metastatic triple‐negative breast cancer patients treated with chemotherapy alone or chemotherapy in combination with immunotherapy. Our data indicate that high gut microbiota alpha diversity was associated with improved clinical outcome and with benefit from immunotherapy.
Andreas Ullern   +8 more
wiley   +1 more source

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