Results 61 to 70 of about 14,456 (265)

A Low-Cost Add-On Sensor and Algorithm to Help Small- and Medium-Sized Enterprises Monitor Machinery and Schedule Processes

Applied Sciences, 2019
Since the concept of Industry 4.0 emerged, an increasing number of major manufacturers have incorporated relevant technologies to monitor machinery and schedule processes so as to increase yield and optimize production. However, most machinery monitoring
Yi-Chung Chen, Kuo-Cheng Ting, Yo-Ming Chen, Don-Lin Yang, Hsi-Min Chen, Josh Jia-Ching Ying   +5 more
doaj   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

A Data-Driven Robust Scheduling Method Integrating Particle Swarm Optimization Algorithm with Kernel-Based Estimation

Applied Sciences, 2021
The assembly job shop scheduling problem (AJSSP) widely exists in the production process of many complex products. Robust scheduling methods aim to optimize the given criteria for improving the robustness of the schedule by organizing the assembly ...
Peng Zheng, Peng Zhang, Ming Wang, Jie Zhang   +3 more
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Design of A Digitalization System for Machine Scheduling and Allocation in Flexible Job Shop Heavy Equipment Manufacturing Industry

Journal of Applied Engineering and Technological Science
This study aims to develop a digitalized scheduling system based on the Flexible Job Shop (FJS) model to optimize production efficiency in the heavy equipment manufacturing industry.
Mohammad Alfin Karim, Taufik Roni Sahroni   +1 more
doaj   +1 more source

The Modelling Methodology of the New Product Release on the Open Market Based on the Production Systems and Rival Products Interaction Dynamics

Proceedings of the International Conference on Applied Innovations in IT, 2020
The relevance of the problem is related to the necessity of improving production systems economical efficiency in constantly changing market conditions and their rivals' behaviour. In the article, it is suggested to use predictions that include diffusion
Leonid Mylnikov, Dmitrii Vershinin, Rustam Faizrahmanov   +2 more
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Artificial Intelligence overview for optimizing production scheduling in a picture framing company

Technical Transactions
Artificial Intelligence is significantly transforming manufacturing and impacting warehouse planning, production, operations, and logistics. This article explores AI applications in these areas, analyzing its role in optimizing scheduling and comparing ...
Krupnik-Worek Jadwiga, Skoczypiec Sebastian, Habel Jacek   +2 more
doaj   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Simulation scheduling in food industry application

Czech Journal of Food Sciences, 2002
Nowadays manufacturers are facing rapid and fundamental changes in the ways business is done. Producers are looking for simulation systems increasing throughput and profit, reducing cycle time, improving due-date performance, reducing WIP, providing ...
S. Simeonov, J. Simeonovová
doaj   +1 more source