Results 61 to 70 of about 78,832 (263)

Schistosoma mansoni infection is associated with quantitative and qualitative modifications of the mammalian intestinal microbiota

Scientific Reports, 2018
In spite of the extensive contribution of intestinal pathology to the pathophysiology of schistosomiasis, little is known of the impact of schistosome infection on the composition of the gut microbiota of its mammalian host.
T. Jenkins, L. Peachey, N. Ajami, A. MacDonald, M. Hsieh, P. Brindley, C. Cantacessi, G. Rinaldi   +7 more
semanticscholar   +1 more source

Identification of β‐galactosidases along the secretory pathway of Nicotiana benthamiana that collectively hamper engineering of galactose‐extended glycans on recombinant glycoproteins

Plant Biotechnology Journal, EarlyView.
Summary Glycosylation is an important aspect for many biopharmaceuticals, including vaccines against parasitic helminths. Plants, especially Nicotiana benthamiana, have proven to be excellent production hosts for biopharmaceuticals with tailor‐made glycosylation.
Alex van der Kaaij, Myrna J. M. Bunte, Lisa Nijhof, Sanaz Mokhtari, Hein Overmars, Arjen Schots, Ruud H. P. Wilbers, Pieter Nibbering   +7 more
wiley   +1 more source

Nanotechnological approaches in the treatment of schistosomiasis: an overview

Beilstein Journal of Nanotechnology
Schistosomiasis causes over 200,000 deaths annually. The current treatment option, praziquantel, presents limitations, including low bioavailability and resistance.
Lucas Carvalho, Michelle Sarcinelli, Beatriz Patrício   +2 more
doaj   +1 more source

Peptide-Alkoxyamine Drugs: An Innovative Approach to Fight Schistosomiasis: “Digging Their Graves with Their Forks”

Pathogens
The expansion of drug resistant parasites sheds a serious concern on several neglected parasitic diseases. Our recent results on cancer led us to envision the use of peptide-alkoxyamines as a highly selective and efficient new drug against schistosome ...
Ange W. Embo-Ibouanga, Michel Nguyen, Jean-Patrick Joly, Mathilde Coustets, Jean-Michel Augereau, Lucie Paloque, Nicolas Vanthuyne, Raphaël Bikanga, Anne Robert, Françoise Benoit-Vical, Gérard Audran, Philippe Mellet, Jérôme Boissier, Sylvain R. A. Marque   +13 more
doaj   +1 more source

The association of Schistosoma mansoni infection with hepatocellular carcinoma

Revista da Sociedade Brasileira de Medicina Tropical, 1984
The association of Schistosoma mansoni infection with hepatocellular carcinoma (HCC) was studied in Espirito Santo State, Brazil. Schistosoma infection was diagnosed by stool examinations or by histological finding at autopsy. HCC was diagnosed by biopsy,
Fausto Edmundo Lima Pereira, Carlos Sandoval Gonçalves   +1 more
doaj   +1 more source

Molecular characterization and distribution of Schistosoma cercariae collected from naturally infected bulinid snails in northern and central Côte d’Ivoire

Parasites & Vectors, 2019
Accurate identification of schistosome species infecting intermediate host snails is important for understanding parasite transmission, schistosomiasis control and elimination.
Yves-Nathan T. Tian-Bi, B. Webster, Cyrille K. Konan, F. Allan, Nana R. Diakité, M. Ouattara, D. Salia, A. Koné, Adolphe K. Kakou, M. Rabone, J. Coulibaly, S. Knopp, Aboulaye Meïté, J. Utzinger, E. N'Goran, D. Rollinson   +15 more
semanticscholar   +1 more source

Photodynamic therapy of cancer‐associated infections

Photochemistry and Photobiology, EarlyView.
Pathogens can be involved in tumor initiation, promotion and progression through different mechanisms, and their treatment can prevent new cancer cases, improve outcomes, and revert poor‐prognostic phenotypes. Photodynamic therapy (PDT) successfully treats different types of cancers and infections, and, therefore, has a unique potential to address ...
Giulia Kassab, Juan Chen, Gang Zheng
wiley   +1 more source

Reduced Efficacy of Praziquantel Against Schistosoma mansoni Is Associated With Multiple Rounds of Mass Drug Administration

Clinical Infectious Diseases, 2016
The efficacy of praziquantel against Schistosoma mansoni was significantly lower in Ugandan schools that had received more prior rounds of mass drug administration, as determined by fitting a statistical model to parasite egg counts before and after ...
Thomas Crellen, M. Walker, P. Lamberton, N. Kabatereine, E. Tukahebwa, J. Cotton, J. Webster   +6 more
semanticscholar   +1 more source

Identification of training needs in schistosomiasis research to build capacity for schistosomiasis control in Uganda

Tropical Medicine &International Health, Volume 30, Issue 4, Page 314-321, April 2025.
Abstract Background Schistosomiasis is the leading cause of fatal upper gastrointestinal bleeding among adults in East Africa. The prevalence among school‐aged children in villages along the Albert–Nile shoreline in North‐Western Uganda is estimated at 85%.
Damalie Nakanjako, Moses Egesa, Helen Byakwaga, Casim Umba Tolo, Anatol Maranda Byaruhanga, Prudence Beinamaryo, Grace Banturaki, Lydia Nakiyingi, Ponsiano Ocama, Moses R. Kamya, Alison M. Elliott   +10 more
wiley   +1 more source

High prevalence of Schistosoma haematobium × Schistosoma bovis hybrids in schoolchildren in Côte d'Ivoire

Parasitology, 2019
Schistosomiasis is a neglected tropical disease, though it is highly prevalent in many parts of sub-Saharan Africa. While Schistosoma haematobium-bovis hybrids have been reported in West Africa, no data about Schistosoma hybrids in humans are available ...
E. Angora, J. Allienne, O. Rey, H. Menan, A. Touré, J. Coulibaly, G. Raso, W. Yavo, E. N'Goran, J. Utzinger, O. Balmer, J. Boissier   +11 more
semanticscholar   +1 more source