Results 71 to 80 of about 123,784 (291)
Clinical Pharmacology &Therapeutics, EarlyView.Novel compounds targeting the adaptive immune system are commonly initially investigated in healthy volunteers (HV). HV frequently lack constitutively expressed drug‐target engagement biomarkers, complicating the evaluation of pharmacological activity. The keyhole limpet hemocyanin (KLH) neo‐antigen challenge elicits a controlled immune response in HV ...
Micha N. Ronner +10 more
wiley +1 more source
Schistosoma japonicum-Associated Colorectal Cancer: A Review.
American Journal of Tropical Medicine and Hygiene, 2019 Schistosoma japonicum is a digenetic blood fluke that has been implicated in the carcinogenesis of several human malignancies, notably liver and colorectal cancer (CRC). Schistosoma japonicum-associated colorectal cancer (SACC) is a distinct subtype with
H. Hamid
semanticscholar +1 more source
Key Regulators of Parasite Biology Viewed Through a Post‐Translational Modification Repertoire
PROTEOMICS, EarlyView.ABSTRACT Parasites are the leading causes of morbidity and mortality in both humans and animals, imposing substantial socioeconomic burdens worldwide. Controlling parasitic diseases has become one of the key issues in achieving “One Health”. Most parasites have sophisticated life cycles exhibiting progressive developmental stages, morphologies, and ...
Naiwen Zhang, Ning Jiang, Qijun Chen
wiley +1 more source
The Schistosoma Granuloma: Friend or Foe? [PDF]
Frontiers in Immunology, 2013 Infection of man with Schistosoma species of trematode parasite causes marked chronic morbidity. Individuals that become infected with Schistosomes may develop a spectrum of pathology ranging from mild cercarial dermatitis to severe tissue inflammation, in particular within the liver and intestines, which can lead to life threatening hepatosplenomegaly.
Hams E., Aviello G., Fallon P. G.
openaire +7 more sources
SCHISTOSOMIASIS, Hubungan Respon Imun dan Perubahan Patologi
Majalah Kedokteran Andalas, 2011 AbstrakSchistosomiasis merupakan suatu penyakit tropik yang disebabkan oleh cacing genus Schistosoma. Spesies yang dapat menginfeksi manusia antara lain Schistosoma mansoni, Schistosoma japonicum, Schistosoma mekongi, Schistosoma haematobium dan ...
Selfi Renita Rusjdi
doaj +1 more source
Transcriptional responses of Biomphalaria pfeifferi and Schistosoma mansoni following exposure to niclosamide, with evidence for a synergistic effect on snails following exposure to both stressors. [PDF]
, 2019 BackgroundSchistosomiasis is one of the world's most common NTDs. Successful control operations often target snail vectors with the molluscicide niclosamide.
Bu, Lijing +5 more
core +2 more sources
Molecular Ecology Resources, EarlyView.ABSTRACT Helminths infect humans, livestock, and wildlife, yet remain understudied despite their significant impact on public health and agriculture. Because many of the most prevalent helminth‐borne diseases are zoonotic, understanding helminth transmission among wildlife could improve predictions and management of infection risks across species.
Chloe A. Fouilloux +12 more
wiley +1 more source
Schistosome Interactions within the Schistosoma haematobium Group, Malawi
Emerging Infectious Diseases, 2019 Molecular analysis of atypical schistosome eggs retrieved from children in Malawi revealed genetic interactions occurring between human (Schistosoma haematobium) and livestock (S. mattheei and S. bovis) schistosome species.
B. Webster +11 more
semanticscholar +1 more source
Development of a laboratorial platform for diagnosis of schistosomiasis mansoni by PCR-ELISA
BMC Research Notes, 2018 Objective We developed a laboratorial platform to release a commercial platform used in the PCR-ELISA for the molecular diagnosis of schistosomiasis mansoni.
Carolina Senra +5 more
doaj +1 more source
Antibodies to glycans dominate the host response to schistosome larvae and eggs: Is their role protective or subversive? [PDF]
, 2001 Multiple exposures of chimpanzees to the radiation-attenuated schistosome vaccine provoked a strong parasite-specific cellular and humoral immune response. Specific IgM and IgG were directed mainly against glycans on antigens released by cercariae; these
Coulson, P.S. +7 more
core +1 more source