Results 21 to 30 of about 64,179 (295)

Protein Kinases: Potential Drug Targets Against Schistosoma japonicum

Frontiers in Cellular and Infection Microbiology, 2021
Schistosoma japonicum (S. japonicum) infection can induce serious organ damage and cause schistosomiasis japonica which is mainly prevalent in Asia and currently one of the most seriously neglected tropical diseases.
Kaijuan Wu, Xingyu Zhai, Shuaiqin Huang, Liping Jiang, Zhengwang Yu, Jing Huang   +5 more
semanticscholar   +1 more source

Bacillus subtilis Attenuates Hepatic and Intestinal Injuries and Modulates Gut Microbiota and Gene Expression Profiles in Mice Infected with Schistosoma japonicum

Frontiers in Cell and Developmental Biology, 2021
Parasitic infection can induce pathological injuries and impact the gut microbiota diversity and composition of the host. Bacillus subtilis is a nonpathogenic and noninvasive probiotic bacterium for humans and other animals, playing an important role in ...
Datao Lin, Qiuyue Song, Yi-shu Zhang, Jiahua Liu, Fang Chen, Shuling Du, Suoyu Xiang, Lifu Wang, Xiaoying Wu, Xi Sun   +9 more
semanticscholar   +1 more source

Proteomics Investigations of Potential Protein Biomarkers in Sera of Rabbits Infected With Schistosoma japonicum

Frontiers in Cellular and Infection Microbiology, 2021
Schistosomiasis is a chronic parasitic disease that continues to be a pressing public health problem in many developing countries. The primary pathological damage from the disease is granuloma and fibrosis caused by egg aggregation, and early treatment ...
N. Bi, Song-Yao Zhao, Jian-feng Zhang, Ying Cheng, Chenxiang Zuo, Gang-Long Yang, Kun Yang   +6 more
semanticscholar   +1 more source

Single-sex schistosome infections of definitive hosts: Implications for epidemiology and disease control in a changing world [PDF]

, 2018
Parasites of the genus Schistosoma cause schistosomiasis, a life-threatening infectious disease for humans and animals worldwide. Among the remarkable biological features of schistosomes is the differentiation of the female gonads which is controlled by ...
A Danso-Appiah, AL Willingham 3rd, AR Harris, BL Webster, C Dye, Carolyn B. Coyne, Da-Bing Lu, DG Colley, E Leger, E Sorensen, GJ van Dam, H Mone, HP Shi, Huan Ding, I Popiel, J Boissier, J Boissier, Joanne P. Webster, JP Webster, JP Webster, JT Ribeiro-Paes, JW Rudge, KC King, KG Weerakoon, L Pica-Mattoccia, LS Qiu, M Dumont, PF Basch, PH Lamberton, PJ Skelly, PT Li, PT Loverde, RM Maizels, S Morand, S Morand, SJ Krauth, T Crellen, W Kunz, Yao Deng, YB Zhou, You-Sheng Liang, ZW Tu   +41 more
core   +8 more sources

Schistosoma japonicum Infection Leads to the Reprogramming of Glucose and Lipid Metabolism in the Colon of Mice

Frontiers in Veterinary Science, 2021
The deposition of Schistosoma japonicum (S. japonicum) eggs commonly induces inflammation, fibrosis, hyperplasia, ulceration, and polyposis in the colon, which poses a serious threat to human health. However, the underlying mechanism is largely neglected.
Xiaoying Yang, Wei-min Ding, Xin-yu Qian, Pengfei Jiang, Qing-qing Chen, Xin Zhang, Yang Lu, Jiacheng Wu, Fen-fen Sun, Zhihua Pan, Xiangyang Li, W. Pan   +11 more
semanticscholar   +1 more source

Thioredoxin glutathione reductase as a novel drug target: evidence from Schistosoma japonicum. [PDF]

PLoS ONE, 2012
BACKGROUND: Schistosomiasis remains a major public health concern affecting billions of people around the world. Currently, praziquantel is the only drug of choice for treatment of human schistosomiasis.
LiJun Song, JiaHuang Li, ShuYing Xie, ChunYan Qian, Jie Wang, Wei Zhang, Xuren Yin, ZiChun Hua, ChuanXin Yu   +8 more
doaj   +1 more source

Alterations of Gut Microbiome and Metabolite Profiling in Mice Infected by Schistosoma japonicum

Frontiers in Immunology, 2020
Schistosoma japonicum (S. japonicum) is one of the etiological agents of schistosomiasis, a widespread zoonotic parasitic disease. However, the mechanism of the balanced co-existence between the host immune system and S.
Yue Hu, Jiansong Chen, Yiyue Xu, Hongli Zhou, Ping Huang, Yubin Ma, Minzhao Gao, Shaoyun Cheng, Haiyun Zhou, Z. Lv   +9 more
semanticscholar   +1 more source

Myricetin Possesses Anthelmintic Activity and Attenuates Hepatic Fibrosis via Modulating TGFβ1 and Akt Signaling and Shifting Th1/Th2 Balance in Schistosoma japonicum-Infected Mice

Frontiers in Immunology, 2020
Schistosomiasis is a zoonotic and debilitating parasitic disease caused by Schistosoma japonicum. Praziquantel remains the choice for treating schistosomiasis, but its efficacy could be hampered by emergence of resistance.
Ping Huang, Minyu Zhou, Shaoyun Cheng, Yue Hu, Minzhao Gao, Yubin Ma, Yanin Limpanont, Hongli Zhou, P. Dekumyoy, Yixin Cheng, Z. Lv   +10 more
semanticscholar   +1 more source

Bionomik Schistosoma japonicum pada Mencit (Mus musculus) di Laboratorium

Jurnal Vektor Penyakit, 2017
Schistosomiasis is still a public health problem in endemic areas. Schistosomiasis in Indonesia was distributed in Napu, Lindu, and Bada Highlands. Schistosomiasis control was complex because so many aspect were related with schistosoma life cycle.
Anis Nurwidayati
doaj   +1 more source

Granuloma formation and tissue pathology in Schistosoma japonicum versus Schistosoma mansoni infections

Parasite immunology (Print), 2020
Schistosomiasis is the most important helminth disease in the world from a public health perspective. S mansoni and S japonicum account for the majority of global intestinal schistosomiasis cases, and the pathogenesis is widely assumed to be ...
Felix Llanwarne, H. Helmby
semanticscholar   +1 more source