Results 21 to 30 of about 65,479 (293)
Pathology and molecular mechanisms of Schistosoma japonicum-associated liver fibrosis
Frontiers in Cellular and Infection Microbiology, 2022 Schistosomiasis has been widely disseminated around the world, and poses a significant threat to human health. Schistosoma eggs and soluble egg antigen (SEA) mediated inflammatory responses promote the formation of egg granulomas and liver fibrosis. With
Zhilong Liu +3 more
semanticscholar +1 more source
Parasites & Vectors, 2022 Background Schistosoma japonicum infection is an important public health problem, imposing heavy social and economic burdens in 78 countries worldwide. However, the mechanism of transition from chronic to advanced S.
Chen Zhou +9 more
semanticscholar +1 more source
Frontiers in Cellular and Infection Microbiology, 2022 The microRNA‐124‐3p plays an important role in regulating development and neurogenesis. Previous microRNA sequencing analyses of Schistosoma japonicum revealed sja-miR-124-3p differential expression patterns in schistosomes from different hosts and at ...
Xue Zhou +5 more
semanticscholar +1 more source
PLoS Pathogens, 2022 Schistosomiasis, which is caused by infection with Schistosoma spp., is characterized by granuloma and fibrosis in response to egg deposition. Pattern recognition receptors are important to sense invading Schistosoma, triggering an innate immune response,
Le Liang +4 more
semanticscholar +1 more source
Alteration of the fecal microbiota in Chinese patients with Schistosoma japonicum infection
Parasite, 2021 Schistosoma japonicum infection causes pathological injury to the host. Multiple studies have shown that intestinal helminth infection causes dysbiosis for the gut microbial community and impacts host immunology. However, the effect of acute S. japonicum
Yan-yan Jiang +8 more
semanticscholar +1 more source
Protein Kinases: Potential Drug Targets Against Schistosoma japonicum
Frontiers in Cellular and Infection Microbiology, 2021 Schistosoma japonicum (S. japonicum) infection can induce serious organ damage and cause schistosomiasis japonica which is mainly prevalent in Asia and currently one of the most seriously neglected tropical diseases.
Kaijuan Wu +5 more
semanticscholar +1 more source
Frontiers in Cell and Developmental Biology, 2021 Parasitic infection can induce pathological injuries and impact the gut microbiota diversity and composition of the host. Bacillus subtilis is a nonpathogenic and noninvasive probiotic bacterium for humans and other animals, playing an important role in ...
Datao Lin +9 more
semanticscholar +1 more source
Thioredoxin glutathione reductase as a novel drug target: evidence from Schistosoma japonicum. [PDF]
PLoS ONE, 2012 BACKGROUND: Schistosomiasis remains a major public health concern affecting billions of people around the world. Currently, praziquantel is the only drug of choice for treatment of human schistosomiasis.
LiJun Song +8 more
doaj +1 more source
Frontiers in Cellular and Infection Microbiology, 2021 Schistosomiasis is a chronic parasitic disease that continues to be a pressing public health problem in many developing countries. The primary pathological damage from the disease is granuloma and fibrosis caused by egg aggregation, and early treatment ...
N. Bi +6 more
semanticscholar +1 more source
Serological Prevalence of Schistosoma japonicum in Mobile Populations in Previously Endemic but Now Non-Endemic Regions of China: A Systematic Review and Meta-Analysis. [PDF]
, 2015 Background: Schistosomiasis japonica has been resurging in certain areas of China where its transmission was previously well controlled or interrupted.
Bian, CR +5 more
core +9 more sources