Results 71 to 80 of about 64,179 (295)

Exploring molecular variation in Schistosoma japonicum in China [PDF]

open access: yesScientific Reports, 2015
AbstractSchistosomiasis is a neglected tropical disease that affects more than 200 million people worldwide. The main disease-causing agents, Schistosoma japonicum, S. mansoni and S. haematobium, are blood flukes that have complex life cycles involving a snail intermediate host. In Asia, S.
Teik Min Chong   +19 more
openaire   +6 more sources

Experimental Schistosoma Japonicum-Induced Pulmonary Hypertension

open access: yesC56. COW HOLLOW: PRECLINICAL MODELS OF PULMONARY HYPERTENSION, 2022
BackgroundSchistosomiasis, a major cause of pulmonary arterial hypertension (PAH) worldwide, is most clearly described complicating infection by one species,Schistosoma mansoni. Controlled exposure of mice can be used to induce Type 2 inflammation-dependentS.mansonipulmonary hypertension (PH).
Biruk Kassa   +7 more
openaire   +5 more sources

Key Regulators of Parasite Biology Viewed Through a Post‐Translational Modification Repertoire

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Parasites are the leading causes of morbidity and mortality in both humans and animals, imposing substantial socioeconomic burdens worldwide. Controlling parasitic diseases has become one of the key issues in achieving “One Health”. Most parasites have sophisticated life cycles exhibiting progressive developmental stages, morphologies, and ...
Naiwen Zhang, Ning Jiang, Qijun Chen
wiley   +1 more source

A prognostic model for Schistosoma japonicum infection-associated liver hepatocellular carcinoma: strengthening the connection through initial biological experiments

open access: yesInfectious Agents and Cancer
Background Numerous studies have shown that Schistosoma japonicum infection correlates with an increased risk of liver hepatocellular carcinoma (LIHC). However, data regarding the role of this infection in LIHC oncogenesis are scarce. This study aimed to
Shuyan Sheng   +13 more
doaj   +1 more source

Proliferation of MDSCs may indicate a lower CD4+ T cell immune response in schistosomiasis japonica

open access: yesParasite
Background: Schistosoma japonicum (S. japonicum) is the main species of Schistosoma prevalent in China. Myeloid-derived suppressor cells (MDSCs) are important immunoregulatory cells and generally expand in parasite infection, but there is little research
Peng Bo   +15 more
doaj   +1 more source

Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry for differential identification of adult Schistosoma worms

open access: yesParasites & Vectors, 2023
Background Schistosomiasis is a major neglected tropical disease that affects up to 250 million individuals worldwide. The diagnosis of human schistosomiasis is mainly based on the microscopic detection of the parasite’s eggs in the feces (i.e., for ...
Jurena Christiane Ebersbach   +5 more
doaj   +1 more source

Photodynamic therapy of cancer‐associated infections

open access: yesPhotochemistry and Photobiology, EarlyView.
Pathogens can be involved in tumor initiation, promotion and progression through different mechanisms, and their treatment can prevent new cancer cases, improve outcomes, and revert poor‐prognostic phenotypes. Photodynamic therapy (PDT) successfully treats different types of cancers and infections, and, therefore, has a unique potential to address ...
Giulia Kassab, Juan Chen, Gang Zheng
wiley   +1 more source

Ko-infeksi Schistosoma Japonicum Dan Soil Transmitted Helminth Di Daerah Endemis Schistosomiasis Kecamatan Lore Utara Dan Lore Timur, Kab. Poso, Sulawesi Tengah [PDF]

open access: yes, 2015
Schistosomiasis due to Schistosoma japonicum are still endemic in Indonesia, especially in Lindu, Sigi Regency, Napu and Bada Plateu, Poso Regency, Central Sulawesi.
Nurwidayati, A. (Anis)   +2 more
core  

Role of a mouse monoclonal IgE antibody in passive transfer of immunity to Schistosoma japonicum infection

open access: yesMemorias do Instituto Oswaldo Cruz, 1987
We have been able to produce a mouse monoclonal IgE antibody specific to an adult worm antigen extracted from Schistosoma japonicum (Sj). The antibody was able to elicit passive cutaneous anaphylaxis in the rat skin against Sj with the highest titer of 1:
Somei Kojima   +3 more
doaj   +1 more source

Pharmacological Inhibition of c‐Jun N‐Terminal Kinase Activity Exacerbates Liver Damage in Schistosoma mansoni Infected Mice

open access: yesLiver International, Volume 45, Issue 9, September 2025.
ABSTRACT Background and Aims Schistosomiasis is a neglected tropical disease affecting more than 250 million people worldwide. Eggs of the parasitic helminth S. mansoni cause major morbidity in the liver, spleen and intestine. Of note, egg‐released soluble antigens (SEA) induce the transcription factor c‐Jun in hepatocytes, promoting hepatocellular ...
Frederik Stettler   +18 more
wiley   +1 more source

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