Results 71 to 80 of about 65,479 (293)

Anti-embryonation immunity in murine schistosomiasis japonica (Philippines)

Memorias do Instituto Oswaldo Cruz, 1995
The hypothesis that granuloma modulation and disease abatement in chronic infection with Schistosoma japonicum could be ascribed to antibody-mediated effects on egg maturation and egg viability, arose from studies performed with mice in the Philippines ...
G. F. Mitchell, E. G. Garcia, K. M. Davern, W. U. Tiu   +3 more
doaj   +1 more source

JQ-1 ameliorates schistosomiasis liver granuloma in mice by suppressing male and female reproductive systems and egg development of Schistosoma japonicum.

PLoS Neglected Tropical Diseases, 2022
Schistosomiasis is a serious and widespread parasitic disease caused by infection with Schistosoma. Because the parasite's eggs are primarily responsible for schistosomiasis dissemination and pathogenesis, inhibiting egg production is a potential ...
Jiaming Tian, Bingxin Dai, Li Gong, Pingping Wang, Han Ding, Siwei Xia, Weice Sun, Cuiping Ren, Jijia Shen, Miao Liu   +9 more
doaj   +1 more source

Low Transmission to Elimination: Rural Development as a Key Determinant of the End-Game Dynamics of Schistosoma japonicum in China. [PDF]

, 2017
Rural development has been a critical component of China's economic miracle since the start of economic reform in the early 1980s, both benefiting from and contributing to the nation's rapid economic growth.
Liang, Song, Spear, Robert, Zhong, Bo
core   +2 more sources

The Longitudinal Impact of Fetal Malnutrition on the Anthropometric Growth of Young Children in Leyte, the Philippines

Maternal &Child Nutrition, Volume 22, Issue 1, March 2026.
ABSTRACT Poor intrauterine growth has long‐term implications for child growth and nutritional status. Fetal malnutrition (FM) is a type of poor intrauterine growth defined by the presence of soft tissue wasting at birth and is identified using the Clinical Assessment of Nutritional Status Score (CANSCORE) tool, independent of gestational age.
Mackenzie E. Bruzzio, Jennifer Friedman, Christopher Barry, Emily McDonald, Blanca Jarilla, Veronica Tallo, Susannah Colt   +6 more
wiley   +1 more source

A prognostic model for Schistosoma japonicum infection-associated liver hepatocellular carcinoma: strengthening the connection through initial biological experiments

Infectious Agents and Cancer
Background Numerous studies have shown that Schistosoma japonicum infection correlates with an increased risk of liver hepatocellular carcinoma (LIHC). However, data regarding the role of this infection in LIHC oncogenesis are scarce. This study aimed to
Shuyan Sheng, Bangjie Chen, Ruiyao Xu, Yanxun Han, Deshen Mao, Yuerong Chen, Conghan Li, Wenzhuo Su, Xinyang Hu, Qing Zhao, Scott Lowe, Yuting Huang, Wei Shao, Yong Yao   +13 more
doaj   +1 more source

Proliferation of MDSCs may indicate a lower CD4+ T cell immune response in schistosomiasis japonica

Parasite
Background: Schistosoma japonicum (S. japonicum) is the main species of Schistosoma prevalent in China. Myeloid-derived suppressor cells (MDSCs) are important immunoregulatory cells and generally expand in parasite infection, but there is little research
Peng Bo, Luo Yulin, Xie Shudong, Zhuang Quan, Li Junhui, Zhang Pengpeng, Liu Kai, Zhang Yu, Zhou Chen, Guo Chen, Zhou Zhaoqin, Zhou Jie, Cai Yu, Xia Meng, Cheng Ke, Ming Yingzi   +15 more
doaj   +1 more source

Vaccines against the zoonotic trematodes Schistosoma japonicum, Fasciola hepatica and Fasciola gigantica [PDF]

, 2006
Schistosoma japonicum, Fasciola hepatica and F. gigantica are digenetic trematodes and, therefore, possess similar life cycles. While schistosomiasis japonica has for a long time been recognised as a major disease of both humans and animals, infection ...
Dalton, JP, McManus, DP
core   +1 more source

Proteomic and deep sequencing analysis of extracellular vesicles isolated from adult male and female Schistosoma japonicum

PLoS Neglected Tropical Diseases, 2020
Schistosomes are the causative agent of schistosomiasis, which affects more than 200 million people worldwide. Unlike other trematode parasites, schistosomes (along with the Didymozoidae) have evolved separate sexes.
Pengfei Du, B. Giri, Juntao Liu, Tianqi Xia, C. Grevelding, G. Cheng   +5 more
semanticscholar   +1 more source

Wnt Signaling Pathway: Biological Function, Diseases, and Therapeutic Interventions

MedComm, Volume 7, Issue 1, January 2026.
The Wnt signaling pathway is essential for development and tissue homeostasis, while its dysregulation drives diverse diseases. This review systematically outlines its components, functions, regulators, and preclinical models, highlighting secreted frizzled‐related proteins (SFRPs) as context‐dependent, biphasic modulators.
Xiaoyu Jin, Jiahui Wang, Runyi Cao, Dongsheng Jiang   +3 more
wiley   +1 more source

Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry for differential identification of adult Schistosoma worms

Parasites & Vectors, 2023
Background Schistosomiasis is a major neglected tropical disease that affects up to 250 million individuals worldwide. The diagnosis of human schistosomiasis is mainly based on the microscopic detection of the parasite’s eggs in the feces (i.e., for ...
Jurena Christiane Ebersbach, Marcello Otake Sato, Matheus Pereira de Araújo, Megumi Sato, Sören L. Becker, Issa Sy   +5 more
doaj   +1 more source