Results 81 to 90 of about 64,179 (295)

The swine flu alert: keeping Asia safe [PDF]

open access: yes, 2009
After years of concern about H5N1 bird flu, the new flu causing global alarm is a pig virus of the H1N1 family. As influenza reports erupt around the world, inevitable questions are arising. Is this the big one?
Balen, J, Caballerho-Anthony, M, Chng, B
core  

Dr. Yang Zhong: an explorer on the road forever [PDF]

open access: yes, 2017
On the morning of September 25th 2017, grievous news spread from the remote Ordos region of Inner Mongolia to Fudan University campus in Shanghai. Professor Yang Zhong, a famous botanist and the Dean of Fudan University’s graduate school, passed away in ...
FA Bisby   +16 more
core   +3 more sources

Genome-wide identification of Schistosoma japonicum microRNAs using a deep-sequencing approach. [PDF]

open access: yesPLoS ONE, 2009
BackgroundHuman schistosomiasis is one of the most prevalent and serious parasitic diseases worldwide. Schistosoma japonicum is one of important pathogens of this disease.
Jian Huang   +6 more
doaj   +1 more source

Sigmoid Schistosomiasis Granuloma Manifested as a Large Painless Supra‐Pubic Mass: A Case Report

open access: yesClinical Case Reports, Volume 13, Issue 8, August 2025.
ABSTRACT Schistosomiasis remains a prevalent parasitic disease in tropical and subtropical regions, ranking second to malaria in terms of parasitic burden. The disease manifests in two primary forms: urinary schistosomiasis, caused by Schistosoma haematobium, and intestinal schistosomiasis, associated with S. mansoni and S. japonicum.
Rawa Badri   +5 more
wiley   +1 more source

The in vivo transcriptome of Schistosoma mansoni in the prominent vector species Biomphalaria pfeifferi with supporting observations from Biomphalaria glabrata. [PDF]

open access: yes, 2019
BackgroundThe full scope of the genes expressed by schistosomes during intramolluscan development has yet to be characterized. Understanding the gene products deployed by larval schistosomes in their snail hosts will provide insights into their ...
Bu, Lijing   +6 more
core   +2 more sources

Enhancing schistosomiasis drug discovery approaches with optimized proteasome substrates

open access: yesProtein Science, Volume 34, Issue 6, June 2025.
Abstract Schistosomiasis, a neglected tropical disease infecting over 200 million people globally, has limited therapeutic options. The 20S proteasome is a validated drug target for many parasitic infections, including those caused by Plasmodium and Leishmania, and we have previously demonstrated antischistosomal activity with inhibitors targeting ...
Elany B. Silva   +12 more
wiley   +1 more source

Expression of microRNA-454 in TGF-β1-stimulated hepatic stellate cells and in mouse livers infected with Schistosoma japonicum

open access: yesParasites & Vectors, 2014
Background In the process of hepatic fibrosis, hepatic stellate cells (HSCs) can be activated by many inflammatory cytokines. The transforming growth factor-β1 (TGF-β1) is one of the main profibrogenic mediators.
Dandan Zhu   +10 more
doaj   +1 more source

Analysis of miR‐10a and IFNG Expression Before and After Treatment for Chronic Schistosomiasis mansoni

open access: yesParasite Immunology, Volume 47, Issue 6, June 2025.
ABSTRACT Mir‐10a acts in signalling pathways regulating transcription, translation, and RNA‐mediated gene silencing, while IFNG acts in the T‐cell receptor signalling pathway. Thus, both can be considered potential targets for understanding regulatory processes in chronic inflammation in patients with schistosomiasis.
Débora Nascimento da Nóbrega   +9 more
wiley   +1 more source

Fragment-based discovery of a regulatory site in thioredoxin glutathione reductase acting as "doorstop" for NADPH entry [PDF]

open access: yes, 2018
Members of the FAD/NAD-linked reductase family are recognized as crucial targets in drug development for cancers, inflammatory disorders, and infectious diseases.
Angelucci, Francesco   +16 more
core   +3 more sources

Development of monoclonal antibodies against Sj29 and its possible application for schistosomiasis diagnosis

open access: yesInternational Journal of Infectious Diseases, 2017
Objective: Timely Schistosoma japonicum detection improves outcomes in schistosomiasis. Here, we established a double antibody sandwich ELISA to detect Schistosoma japonicum.
Cui-Ping Ren   +9 more
doaj   +1 more source

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