Metagenomic analysis of the intestinal microbiome reveals the potential mechanism involved in Bacillus amyloliquefaciens in treating schistosomiasis japonica in mice [PDF]
Schistosomiasis japonica is one of the neglected tropical diseases characterized by chronic hepatic, intestinal granulomatous inflammation and fibrosis, as well as dysbiosis of intestinal microbiome.
Hao Chen+7 more
doaj +3 more sources
Circulating microRNAs as Biomarkers of Hepatic Fibrosis in Schistosomiasis Japonica Patients in the Philippines [PDF]
Host-derived microRNAs (miRNAs) play important regulatory roles in schistosomiasis-induced hepatic fibrosis. This study analyzed selected serum miRNAs among Filipino schistosomiasis japonica patients with ultrasound (US)-detectable hepatic fibrosis.
Ian Kim B. Tabios+11 more
doaj +3 more sources
Transmission-Blocking Vaccines against Schistosomiasis Japonica. [PDF]
Control of schistosomiasis japonica, endemic in Asia, including the Philippines, China, and Indonesia, is extremely challenging. Schistosoma japonicum is a highly pathogenic helminth parasite, with disease arising predominantly from an immune reaction to entrapped parasite eggs in tissues.
Zumuk CP+4 more
europepmc +4 more sources
Development of a latex microsphere-based lateral flow immunoassay for the diagnosis of schistosomiasis japonica. [PDF]
BackgroundZoonotic schistosomiasis, caused by Schistosoma japonicum, is prevalent in China, the Philippines and Indonesia. Rapid point-of-care (POC) diagnostics are attractive and promising tools for evaluating the efficacy of intervention strategies for
Emmanuel John Tabilin+16 more
doaj +3 more sources
Comparative assessment of the SjSAP4-incorporated gold immunochromatographic assay for the diagnosis of human schistosomiasis japonica. [PDF]
Background Schistosomiasis, a disease caused by parasites of the genus Schistosoma, remains a global public health threat. This study aimed to validate the diagnostic performance of a recently developed gold immunochromatographic assay (GICA) for the ...
Mu Y+9 more
europepmc +4 more sources
Short-Term Efficacy of Laparoscopic Treatment for Colorectal Cancer in Patients with Schistosomiasis Japonica [PDF]
Introduction. Schistosomiasis is associated with numerous complications such as thrombocytopenia, liver cirrhosis, portal hypertension, and colitis. To the best of our knowledge, the feasibility and outcomes of laparoscopic colorectal surgery in patients
Zhu Yi+3 more
doaj +3 more sources
Two Molecular Plasma-Based Diagnostic Methods to Evaluate Early Infection of Schistosoma japonicum and Schistosomiasis Japonica. [PDF]
The prevalence and infectious intensity of schistosomiasis japonica has decreased significantly in China in the past few decades. However, more accurate and sensitive diagnostic methods are urgently required for the further control, surveillance, and ...
Hong Y+13 more
europepmc +4 more sources
A novel fluorescence immunochromatographic assay strip for the diagnosis of schistosomiasis japonica. [PDF]
Schistosomiasis japonica is a severe zoonosis. Domestic animals are the primary source of infection and play an important role in disease transmission. Surveillance and diagnosis play key roles in schistosomiasis control; however, current techniques for ...
Shen Y+10 more
europepmc +4 more sources
The status of schistosomiasis japonica control in the Philippines: The need for an integrated approach to address a multidimensional problem [PDF]
Schistosomiasis japonica remains a public health concern in many areas of the Philippines. Adequate and updated information is essential to enhance policy and service delivery toward control and elimination. Despite the efforts on schistosomiasis control
Vicente Y. Belizario, Jr.+7 more
doaj +2 more sources
High-throughput autoantibody profiling of different stages of Schistosomiasis japonica
Infection by the Schistosoma japonicum can result in acute, chronic and late-stage manifestations. The latter often presents with severe organ failures and premature death.
Xiaorong Zhou+6 more
doaj +2 more sources