Inhibition of COX-2 ameliorates murine liver schistosomiasis japonica through splenic cellular immunoregulation. [PDF]
Background We have reported the positive association of the cyclooxygenase 2 (COX-2)/prostaglandin E2 (PGE2) axis with liver fibrosis induced by Schistosoma japonicum ( Sj ) infection, and TLR4 signaling controlled this axis. However, how COX-2 regulates
Qi Z+7 more
europepmc +4 more sources
Circulating microRNAs as Biomarkers of Hepatic Fibrosis in Schistosomiasis Japonica Patients in the Philippines [PDF]
Host-derived microRNAs (miRNAs) play important regulatory roles in schistosomiasis-induced hepatic fibrosis. This study analyzed selected serum miRNAs among Filipino schistosomiasis japonica patients with ultrasound (US)-detectable hepatic fibrosis.
Ian Kim B. Tabios+11 more
doaj +3 more sources
A novel fluorescence immunochromatographic assay strip for the diagnosis of schistosomiasis japonica. [PDF]
Schistosomiasis japonica is a severe zoonosis. Domestic animals are the primary source of infection and play an important role in disease transmission. Surveillance and diagnosis play key roles in schistosomiasis control; however, current techniques for ...
Shen Y+10 more
europepmc +4 more sources
Development of a Recombinase Polymerase Amplification Assay for Schistosomiasis Japonica Diagnosis in the Experimental Mice and Domestic Goats [PDF]
Although the prevalence of schistosomiasis japonica has declined gradually in China, more accurate and sensitive diagnostic methods are urgently needed for the prevention and control of this disease. Molecular diagnostic methods are advantageous in terms
Qinghong Guo+22 more
doaj +3 more sources
Development of a latex microsphere-based lateral flow immunoassay for the diagnosis of schistosomiasis japonica. [PDF]
BackgroundZoonotic schistosomiasis, caused by Schistosoma japonicum, is prevalent in China, the Philippines and Indonesia. Rapid point-of-care (POC) diagnostics are attractive and promising tools for evaluating the efficacy of intervention strategies for
Emmanuel John Tabilin+16 more
doaj +3 more sources
Transmission-Blocking Vaccines against Schistosomiasis Japonica. [PDF]
Control of schistosomiasis japonica, endemic in Asia, including the Philippines, China, and Indonesia, is extremely challenging. Schistosoma japonicum is a highly pathogenic helminth parasite, with disease arising predominantly from an immune reaction to
Zumuk CP+4 more
europepmc +4 more sources
Estimating the prevalence of schistosomiasis japonica in China: a serological approach. [PDF]
BackgroundThe prevalence of schistosomiasis japonica has decreased significantly, and the responses changing from control to elimination in Jiangsu Province, P.R. China.
Wang XY+7 more
europepmc +4 more sources
Development and assessment of a novel gold immunochromatographic assay for the diagnosis of schistosomiasis japonica. [PDF]
Background The neglected zoonosis, schistosomiasis japonica, remains a major public health problem in the Philippines. The current study aims to develop a novel gold immunochromatographic assay (GICA) and evaluate its performance in the detection of ...
Mu Y+6 more
europepmc +2 more sources
The status of schistosomiasis japonica control in the Philippines: The need for an integrated approach to address a multidimensional problem [PDF]
Schistosomiasis japonica remains a public health concern in many areas of the Philippines. Adequate and updated information is essential to enhance policy and service delivery toward control and elimination. Despite the efforts on schistosomiasis control
Vicente Y. Belizario, Jr.+7 more
doaj +2 more sources
Network Analysis and Nomogram in the Novel Classification and Prognosis Prediction of Advanced Schistosomiasis Japonica. [PDF]
. Clinical classification of advanced schistosomiasis japonica is important for treatment options and prognosis prediction. Network analysis was used to solve the problem of complexity and co-occurrence complications in classification of advanced ...
Liu XF, Li Y, Ju S, Zhou YL, Qiang JW.
europepmc +2 more sources