Serum non‐coding RNAs for diagnosis and stage of liver fibrosis
MicroRNAs, lncRNAs, circRNAs and exosomes which were released from liver enter into circulating vessels. The blood which contain these molecules are drawed from patients. Then the blood specimen are tested for diagnose of early fibrosis or stage fibrosis in patients with liver diseases. Abstract Background All chronic liver diseases could lead to liver
Chao Liu +6 more
wiley +1 more source
Schistosomiasis remains a major global public health concern. Currently, the control of this neglected tropical disease still depends on chemotherapy to reduce the prevalence and intensity of the parasite infection. It has been widely accepted that praziquantel is highly effective against all species of Schistosoma, and this agent is virtually the only
Xuehua Niu +5 more
wiley +1 more source
Field comparison of circulating antibody assays versus circulating antigen assays for the detection of Schistosomiasis japonica in endemic areas of China [PDF]
Schistosomiasis remains a serious public health problem in affected countries, and routine, highly sensitive and cost-effective diagnostic methods are lacking.
Peter Steinmann +23 more
core +1 more source
Higher frequency of circulating Vδ1 γδT cells in patients with advanced schistosomiasis
Abstract Gamma‐delta (γδ) T cells are the bridge between natural and adaptive immunity. In the present study, peripheral blood was collected from 13 patients with advanced schistosomiasis (schistosomiasis group) and 13 uninfected people (control group) to investigate the γδ T cells and their subtypes in human schistosomiasis.
Li Zheng +8 more
wiley +1 more source
Health access livelihood framework reveals potential barriers in the control of schistosomiasis in the Dongting Lake area of Hunan Province, China [PDF]
Background:Access to health care is a major requirement in improving health and fostering socioeconomic development. In the People's Republic of China (P.R.
Utzinger, Jürg +36 more
core +2 more sources
A randomized, double-blind, placebo-controlled trial of safety and efficacy of combined praziquantel and artemether treatment for acute schistosomiasis japonica in China. [PDF]
OBJECTIVE: To evaluate the safety and efficacy of combining artemether (AM) and praziquantel (PZQ) in different regimens for treating acute schistosomiasis japonica.
Gray, Darren J. +22 more
core +1 more source
Tools to support policy decisions related to treatment strategies and surveillance of Schistosomiasis japonica towards elimination. [PDF]
BACKGROUND: Appropriate diagnostics to monitor disease trends and assess the effectiveness and impact of interventions are essential for guiding treatment strategies at different thresholds of schistosomiasis transmission and for certifying elimination ...
Lin, Dan-Dan +50 more
core +2 more sources
PAMAM-Lys, a novel vaccine delivery vector, enhances the protective effects of the SjC23 DNA vaccine against Schistosoma japonicum infection. [PDF]
BACKGROUND: Schistosomiasis japonica remains a major public-health concern in China. Praziquantel-based chemotherapy effectively reduces both infections and intensity; however, it can not prevent re-infection.
Xiaoting Wang +10 more
doaj +1 more source
Schistosomiasis japonica caused by the trematode flukes of Schistosoma japonicum was one of the most grievous infectious diseases in China in the mid-20th century, while its elimination has been placed on the agenda of the national strategic plan of ...
Chao Lv +5 more
doaj +1 more source
Spatio-temporal analysis to identify determinants of Oncomelania hupensis infection with Schistosoma japonicum in Jiangsu province, China [PDF]
With the successful implementation of integrated measures for schistosomiasis japonica control, Jiangsu province has reached low-endemicity status. However, infected Oncomelania hupensis snails could still be found in certain locations along the Yangtze ...
Huang, Yi-Xin +9 more
core +1 more source

