Results 31 to 40 of about 1,608 (156)

PAMAM-Lys, a novel vaccine delivery vector, enhances the protective effects of the SjC23 DNA vaccine against Schistosoma japonicum infection. [PDF]

PLoS ONE, 2014
BACKGROUND: Schistosomiasis japonica remains a major public-health concern in China. Praziquantel-based chemotherapy effectively reduces both infections and intensity; however, it can not prevent re-infection.
Xiaoting Wang, Yang Dai, Song Zhao, Jianxia Tang, Hongjun Li, Yuntian Xing, Guoli Qu, Xinsong Li, Jianrong Dai, Yinchang Zhu, Xueguang Zhang   +10 more
doaj   +1 more source

Molecular Techniques as Alternatives of Diagnostic Tools in China as Schistosomiasis Moving towards Elimination

Pathogens, 2022
Schistosomiasis japonica caused by the trematode flukes of Schistosoma japonicum was one of the most grievous infectious diseases in China in the mid-20th century, while its elimination has been placed on the agenda of the national strategic plan of ...
Chao Lv, Wangping Deng, Liping Wang, Zhiqiang Qin, Xiaonong Zhou, Jing Xu   +5 more
doaj   +1 more source

Noninvasive diagnosis of liver fibrosis in schistosomiasis japonica: Opportunities and challenges

, 2023
Portal Hypertension &Cirrhosis, Volume 2, Issue 1, Page 43-45, March 2023.
Tao Wang, HaiYong Hua, JianFeng Zhang, Wei Li, Kun Yang   +4 more
wiley   +1 more source

IgG persistence showed weak clinical aspects in chronic schistosomiasis patients

Scientific Reports, 2023
Schistosomiasis is a chronic parasitic disease, which affects the quality of daily life of patients and imposes a huge burden on society. Hepatic fibrosis in response to continuous insult of eggs to the liver is a significant cause of morbidity and ...
Shudong Xie, Yu Zhang, Junhui Li, Jie Zhou, Jun Li, Pengpeng Zhang, Yang Liu, Yulin Luo, Yingzi Ming   +8 more
doaj   +1 more source

A diagnostic challenge for schistosomiasis japonica in China: consequences on praziquantel-based morbidity control

Parasites & Vectors, 2011
Worldwide schistosomiasis continues to be a serious public health problem. Over the past five decades, China has made remarkable progress in reducing Schistosoma japonicum infections in humans to a relatively low level.
Zheng Hui-min, Zhou Yi-biao, Jiang Qing-wu   +2 more
doaj   +1 more source

A CASE OF SCHISTOSOMIASIS JAPONICA. [PDF]

The Lancet, 1914
n ...
openaire   +1 more source

P21 activated kinase‐1 (PAK1) in macrophages is required for promotion of Th17 cell response during helminth infection

Journal of Cellular and Molecular Medicine, Volume 24, Issue 24, Page 14325-14338, December 2020., 2020
Abstract CD4+T cells differentiate into distinct functional effector and inhibitory subsets are facilitated by distinct cytokine cues present at the time of antigen recognition. Maintaining a balance between T helper 17 (Th17) and regulatory T (Treg) cells are critical for the control of the immunopathogenesis of liver diseases.
Hao Chang, Kai‐Yue He, Chen Li, Yang‐Yue Ni, Mai‐Ning Li, Lin Chen, Min Hou, Zikai Zhou, Zhi‐Peng Xu, Min‐Jun Ji   +9 more
wiley   +1 more source

Follicular helper T cells recruit eosinophils into host liver by producing CXCL12 during Schistosoma japonicum infection

Journal of Cellular and Molecular Medicine, Volume 24, Issue 4, Page 2566-2572, February 2020., 2020
Abstract Schistosomiasis affects at least 200 million people in tropical and subtropical areas. The major pathology of schistosomiasis is egg‐induced liver granuloma characterized by an eosinophil‐rich inflammatory infiltration around the eggs, which subsequently leads to hepatic fibrosis and circulatory impairment in host.
Xiaojun Chen, Zhipeng Xu, Chuan Wei, XiaoWei Yang, Lei Xu, Sha Zhou, Jifeng Zhu, Chuan Su   +7 more
wiley   +1 more source

Sedum sarmentosum Total Flavonoids Alleviate Schistosomiasis‐Induced Liver Fibrosis by Altering TGF‐β1 and Smad7 Expression

Evidence-Based Complementary and Alternative Medicine, Volume 2020, Issue 1, 2020., 2020
Objectives. Schistosomiasis is a parasitic disease that affects over 142 million people worldwide. The main causes of death of schistosomiasis include liver granuloma and secondary hepatic cirrhosis resulting from severe fibrosis. Despite intensive research, controlling liver fibrosis associated with schistosomiasis remains challenging.
Peng-chun Yang, Wei-zhe Bai, Jing Wang, Cai-hua Yan, Wei-feng Huang, Shi-zhu Jiang, Konrad Urech   +6 more
wiley   +1 more source

Elimination of Schistosoma japonica in Central Sulawesi, Indonesia Intermediate Snail Control and Utilization Medicinal Plants

Journal of Parasite Science
Schistosomiasis is a zoonotic health problem caused by infection with the schistosoma class parasite, which lives in human blood vessels and around the intestines and bladder.
Acivrida Mega Charisma, Anjelline Naftalia, Alfian Anwar Putra Ramadhan, Rasyida Salma Aulia, Ferdina Amalia Solikhah, Husnul Muasyaroh, Vina Lailatul Maslakha, Nurul Hikmah, Ken Dyah Ayu Belina, Hilda Adinda, Siska Wulandari   +10 more
doaj   +1 more source