Results 31 to 40 of about 1,542 (158)

Noninvasive diagnosis of liver fibrosis in schistosomiasis japonica: Opportunities and challenges

open access: yes, 2023
Portal Hypertension &Cirrhosis, Volume 2, Issue 1, Page 43-45, March 2023.
Tao Wang   +4 more
wiley   +1 more source

IgG persistence showed weak clinical aspects in chronic schistosomiasis patients

open access: yesScientific Reports, 2023
Schistosomiasis is a chronic parasitic disease, which affects the quality of daily life of patients and imposes a huge burden on society. Hepatic fibrosis in response to continuous insult of eggs to the liver is a significant cause of morbidity and ...
Shudong Xie   +8 more
doaj   +1 more source

Molecular Techniques as Alternatives of Diagnostic Tools in China as Schistosomiasis Moving towards Elimination

open access: yesPathogens, 2022
Schistosomiasis japonica caused by the trematode flukes of Schistosoma japonicum was one of the most grievous infectious diseases in China in the mid-20th century, while its elimination has been placed on the agenda of the national strategic plan of ...
Chao Lv   +5 more
doaj   +1 more source

A diagnostic challenge for schistosomiasis japonica in China: consequences on praziquantel-based morbidity control

open access: yesParasites & Vectors, 2011
Worldwide schistosomiasis continues to be a serious public health problem. Over the past five decades, China has made remarkable progress in reducing Schistosoma japonicum infections in humans to a relatively low level.
Zheng Hui-min   +2 more
doaj   +1 more source

P21 activated kinase‐1 (PAK1) in macrophages is required for promotion of Th17 cell response during helminth infection

open access: yesJournal of Cellular and Molecular Medicine, Volume 24, Issue 24, Page 14325-14338, December 2020., 2020
Abstract CD4+T cells differentiate into distinct functional effector and inhibitory subsets are facilitated by distinct cytokine cues present at the time of antigen recognition. Maintaining a balance between T helper 17 (Th17) and regulatory T (Treg) cells are critical for the control of the immunopathogenesis of liver diseases.
Hao Chang   +9 more
wiley   +1 more source

Follicular helper T cells recruit eosinophils into host liver by producing CXCL12 during Schistosoma japonicum infection

open access: yesJournal of Cellular and Molecular Medicine, Volume 24, Issue 4, Page 2566-2572, February 2020., 2020
Abstract Schistosomiasis affects at least 200 million people in tropical and subtropical areas. The major pathology of schistosomiasis is egg‐induced liver granuloma characterized by an eosinophil‐rich inflammatory infiltration around the eggs, which subsequently leads to hepatic fibrosis and circulatory impairment in host.
Xiaojun Chen   +7 more
wiley   +1 more source

Sedum sarmentosum Total Flavonoids Alleviate Schistosomiasis‐Induced Liver Fibrosis by Altering TGF‐β1 and Smad7 Expression

open access: yesEvidence-Based Complementary and Alternative Medicine, Volume 2020, Issue 1, 2020., 2020
Objectives. Schistosomiasis is a parasitic disease that affects over 142 million people worldwide. The main causes of death of schistosomiasis include liver granuloma and secondary hepatic cirrhosis resulting from severe fibrosis. Despite intensive research, controlling liver fibrosis associated with schistosomiasis remains challenging.
Peng-chun Yang   +6 more
wiley   +1 more source

Long‐Term Traditional Chinese Medicine Combined with NA Antiviral Therapy on Cirrhosis Incidence in Chronic Hepatitis B Patients in the Real‐World Setting: A Retrospective Study

open access: yesEvidence-Based Complementary and Alternative Medicine, Volume 2020, Issue 1, 2020., 2020
Objective. To evaluate the impact of long‐term Traditional Chinese Medicine (TCM) syndrome differentiation combined with antiviral therapy with Nucleos (t) ide analogues (NAs) on the incidence of cirrhosis in patients with chronic hepatitis B. Methods.
Zhi-Jun Hou   +12 more
wiley   +1 more source

Current Status of Schistosomiasis Control and Prospects for Elimination in the Dongting Lake Region of the People’s Republic of China

open access: yesFrontiers in Immunology, 2020
Schistosomiasis japonica is an ancient parasitic disease that has severely impacted human health causing a substantial disease burden not only to the Chinese people but also residents of other countries such as the Philippines, Indonesia and, before the ...
Fei-Yue Li   +12 more
doaj   +1 more source

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