Results 41 to 50 of about 3,460 (196)

Assessment of morbidity due to Schistosoma japonicum infection in China [PDF]

open access: yes, 2014
This paper presents a historical assessment of morbidity due to the Schistosoma japonicum infection in China. Due to the socio-economic situation, which did not allow for a control program to be implemented until the early 1950s, morbidity was serious ...
Ming-gang Chen
core   +1 more source

P21 activated kinase‐1 (PAK1) in macrophages is required for promotion of Th17 cell response during helminth infection

open access: yesJournal of Cellular and Molecular Medicine, Volume 24, Issue 24, Page 14325-14338, December 2020., 2020
Abstract CD4+T cells differentiate into distinct functional effector and inhibitory subsets are facilitated by distinct cytokine cues present at the time of antigen recognition. Maintaining a balance between T helper 17 (Th17) and regulatory T (Treg) cells are critical for the control of the immunopathogenesis of liver diseases.
Hao Chang   +9 more
wiley   +1 more source

Follicular helper T cells recruit eosinophils into host liver by producing CXCL12 during Schistosoma japonicum infection

open access: yesJournal of Cellular and Molecular Medicine, Volume 24, Issue 4, Page 2566-2572, February 2020., 2020
Abstract Schistosomiasis affects at least 200 million people in tropical and subtropical areas. The major pathology of schistosomiasis is egg‐induced liver granuloma characterized by an eosinophil‐rich inflammatory infiltration around the eggs, which subsequently leads to hepatic fibrosis and circulatory impairment in host.
Xiaojun Chen   +7 more
wiley   +1 more source

A strategy for emergency treatment of Schistosoma japonicum-infested water [PDF]

open access: yes, 2011
Background Schistosomiasis japonica, caused by contact with Schistosoma japonicum cercaria-infested water when washing, bathing or production, remains a major public-health concern in China.
You-Sheng Liang   +8 more
core   +2 more sources

Sedum sarmentosum Total Flavonoids Alleviate Schistosomiasis‐Induced Liver Fibrosis by Altering TGF‐β1 and Smad7 Expression

open access: yesEvidence-Based Complementary and Alternative Medicine, Volume 2020, Issue 1, 2020., 2020
Objectives. Schistosomiasis is a parasitic disease that affects over 142 million people worldwide. The main causes of death of schistosomiasis include liver granuloma and secondary hepatic cirrhosis resulting from severe fibrosis. Despite intensive research, controlling liver fibrosis associated with schistosomiasis remains challenging.
Peng-chun Yang   +6 more
wiley   +1 more source

Long‐Term Traditional Chinese Medicine Combined with NA Antiviral Therapy on Cirrhosis Incidence in Chronic Hepatitis B Patients in the Real‐World Setting: A Retrospective Study

open access: yesEvidence-Based Complementary and Alternative Medicine, Volume 2020, Issue 1, 2020., 2020
Objective. To evaluate the impact of long‐term Traditional Chinese Medicine (TCM) syndrome differentiation combined with antiviral therapy with Nucleos (t) ide analogues (NAs) on the incidence of cirrhosis in patients with chronic hepatitis B. Methods.
Zhi-Jun Hou   +12 more
wiley   +1 more source

Current Status of Schistosomiasis Control and Prospects for Elimination in the Dongting Lake Region of the People’s Republic of China

open access: yesFrontiers in Immunology, 2020
Schistosomiasis japonica is an ancient parasitic disease that has severely impacted human health causing a substantial disease burden not only to the Chinese people but also residents of other countries such as the Philippines, Indonesia and, before the ...
Fei-Yue Li   +12 more
doaj   +1 more source

Circulating miRNAs: Potential Novel Biomarkers for Hepatopathology Progression and Diagnosis of Schistosomiasis Japonica in Two Murine Models. [PDF]

open access: yesPLoS Neglected Tropical Diseases, 2015
Schistosomiasis remains a major public health issue, with an estimated 230 million people infected worldwide. Novel tools for early diagnosis and surveillance of schistosomiasis are currently needed.
Pengfei Cai   +4 more
doaj   +1 more source

The basic reproductive ratio of Barbour's two-host schistosomiasis model with seasonal fluctuations [PDF]

open access: yes, 2017
Motivated by the first mathematical model for schistosomiasis proposed by Macdonald and Barbour's classical schistosomiasis model tracking the dynamics of infected human population and infected snail hosts in a community, in our previous study, we ...
Cao, Hua-Hua   +6 more
core   +2 more sources

Elimination of Schistosoma japonica in Central Sulawesi, Indonesia Intermediate Snail Control and Utilization Medicinal Plants

open access: yesJournal of Parasite Science
Schistosomiasis is a zoonotic health problem caused by infection with the schistosoma class parasite, which lives in human blood vessels and around the intestines and bladder.
Acivrida Mega Charisma   +10 more
doaj   +1 more source

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