Results 61 to 70 of about 1,608 (156)

A novel immunodiagnostic assay to detect serum antibody response against selected soluble egg antigen fractions from Schistosoma japonicum. [PDF]

PLoS ONE, 2012
BACKGROUND: Schistosomiasis japonica remains a real threat to public health in China. The currently used immunodiagnostic assays are sensitive and have a certain degree of specificity, however, they all use complex crude antigens, are based on detection ...
Yinchang Zhu, Wanquan Hua, Ming Xu, Wei He, Xiaoting Wang, Yang Dai, Song Zhao, Jianxia Tang, Shixia Wang, Shan Lu   +9 more
doaj   +1 more source

Schistosomiasis Chemotherapy, Chemoprevention, and Vaccines: History, Progress, and Priorities

Immunity, Inflammation and Disease, Volume 12, Issue 11, November 2024.
Schistosomiasis is a major human disease of public health importance. The goal is to provide an overview of the history and advancements in schistosomiasis chemotherapy, chemoprevention, and vaccine research. Praziquantel is effective against all species of schistosomiasis, but schistosomiasis prevalence has largely remained unaffected, due to ...
Alaa Oqalaa E. Alibrahim, Walaa A. Elkholy, Mona M. El‐Derbawy, Noha F. Zahran, Athanasios Alexiou, Marios Papadakis, Gaber El‐Saber Batiha   +6 more
wiley   +1 more source

A Parallel Comparison of Antigen Candidates for Development of an Optimized Serological Diagnosis of Schistosomiasis Japonica in the Philippines

EBioMedicine, 2017
Schistosoma japonicum is stubbornly persistent in China and the Philippines. Fast and accurate diagnostic tools are required to monitor effective control measures against schistosomiasis japonica.
Pengfei Cai, Kosala G. Weerakoon, Yi Mu, David U. Olveda, Xianyu Piao, Shuai Liu, Remigio M. Olveda, Qijun Chen, Allen G. Ross, Donald P. McManus   +9 more
doaj   +1 more source

Parasite‐derived microRNA let‐7‐5p detection for metacestodiasis based on rolling circular amplification‐assisted CRISPR/Cas9

The FASEB Journal, Volume 38, Issue 10, 31 May 2024.
MicroRNA extraction and RCA‐assisted CRISPR/Cas9 detection. Abstract Metacestodiasis is an infectious disease caused by the larval stage of cestode parasites. This disease poses a serious health hazard to wildlife, livestock, and humans, and it incurs substantial economic losses by impacting the safety of the livestock industry, the quality of meat ...
Liqun Wang, Guiting Pu, Tingli Liu, Guoliang Chen, Hong Li, Tharheer Oluwashola Amuda, Shanling Cao, Hongbin Yan, Hong Yin, Baoquan Fu, Xuenong Luo   +10 more
wiley   +1 more source

Real-time PCR demonstrates high prevalence of Schistosoma japonicum in the Philippines: implications for surveillance and control.

PLoS Neglected Tropical Diseases, 2015
BackgroundThe Philippines has a population of approximately 103 million people, of which 6.7 million live in schistosomiasis-endemic areas with 1.8 million people being at risk of infection with Schistosoma japonicum. Although the country-wide prevalence
Catherine A Gordon, Luz P Acosta, Geoffrey N Gobert, Remigio M Olveda, Allen G Ross, Gail M Williams, Darren J Gray, Donald Harn, Yuesheng Li, Donald P McManus   +9 more
doaj   +1 more source

Schistosome eggs stimulate reactive oxygen species production to enhance M2 macrophage differentiation and promote hepatic pathology in schistosomiasis.

PLoS Neglected Tropical Diseases, 2021
Schistosomiasis is a neglected tropical disease of public health concern. The most devastating pathology in schistosomiasis japonica and mansoni is mainly attributed to the egg-induced granulomatous response and secondary fibrosis in host liver, which ...
Yanxiong Yu, Junling Wang, Xiaohong Wang, Pan Gu, Zhigang Lei, Rui Tang, Chuan Wei, Lei Xu, Chun Wang, Ying Chen, Yanan Pu, Xin Qi, Beibei Yu, Xiaojun Chen, Jifeng Zhu, Yalin Li, Zhijie Zhang, Sha Zhou, Chuan Su   +18 more
doaj   +1 more source

One Health and Zoonotic Diseases: A Collaborative Approach to Global Health

Animal Research and One Health, Volume 3, Issue 2, Page 146-148, May 2025.
Peng Li, Jiabo Ding
wiley   +1 more source

Schistosoma japonicum EKLF/KLF1 is a potential immune target to tackle schistosomiasis

Parasites & Vectors, 2023
Background Interruption of parasite reproduction by targeting migrating schistosomula is a promising strategy for managing schistosomiasis. Hepatic schistosomula proteins previously identified based on second-generation schistosome DNA sequencing were ...
Xianyu Piao, Ning Jiang, Shuai Liu, Jiamei Duan, Hang dai, Nan Hou, Qijun Chen   +6 more
doaj   +1 more source

Composition and Laboratory Examination Characteristics of 187 Colorectal Cancer Patients with Schistosomiasis

Zhongliu Fangzhi Yanjiu, 2019
Objective To analyze whether schistosomiasis japonica has a certain correlation with the occurrence of intestinal cancer and investigate the characteristics of intestinal cancer with schistosomiasis. Methods We retrospectively analyzed the clinical data,
YANG Jianghua, DU Zhixiang, XUAN Kun, WANG Wenjie, SHENG Haoyu   +4 more
doaj   +1 more source

Schistosomiasis control in China

Memorias do Instituto Oswaldo Cruz, 1995
After three decades' efforts, schistosomiasis japonica were controlled in one-third (4/12) of endemic provinces and 68.2 (259/380) of endemic counties throughout the country.
Hong-Chang Yuan
doaj   +1 more source