Results 51 to 60 of about 1,608 (156)

Gut Microbiota Modulates Intestinal Pathological Injury in Schistosoma japonicum-Infected Mice

open access: yesFrontiers in Medicine, 2020
Trapping of Schistosoma japonicum (S. japonicum) eggs in host tissue, mainly in the intestine and liver, causes severe gastrointestinal and hepatic granulomatous immune responses and irreversible fibrosis. Although the gut microbiota plays a central role
Beibei Zhang   +26 more
doaj   +1 more source

Multiple Key Hosts and Network Structure Shape Viral Prevalence Across Multispecies Communities of Bees

open access: yesEcology Letters, Volume 29, Issue 2, February 2026.
This study develops a quantitative framework that integrates field data, epidemiological models, simulations, and Bayesian inference to identify key viral hosts in multispecies bee communities. By estimating species‐specific R0 values from flower‐visitor networks and viral screening, we show that honeybees, as well as other wild bees, can drive the ...
Patrycja Pluta   +4 more
wiley   +1 more source

Biological invasions: a global assessment of geographic distributions, long‐term trends, and data gaps

open access: yesBiological Reviews, Volume 100, Issue 6, Page 2542-2583, December 2025.
ABSTRACT Biological invasions are one of the major drivers of biodiversity decline and have been shown to have far‐reaching consequences for society and the economy. Preventing the introduction and spread of alien species represents the most effective solution to reducing their impacts on nature and human well‐being.
Hanno Seebens   +64 more
wiley   +1 more source

An association of Aquaporin-4 with the immunoregulation of liver pathology in mice infected with Schistosoma japonicum

open access: yesParasites & Vectors, 2015
Background Schistosomiasis is a chronic parasitic disease that affects approximately 200 million people. In Schistosomiasis japonica and mansoni, parasite eggs were trapped in host liver and stimulated the CD4+T cell responses to regulate the formation ...
Weiwei Zhang   +13 more
doaj   +1 more source

Real-time observation of pathophysiological processes during murine experimental Schistosoma japonicum infection using high-resolution ultrasound imaging

open access: yesTropical Medicine and Health, 2018
Background Hepatosplenic lesion formation is one of the typical clinical symptoms of schistosomiasis japonica. Although it is established that circum-oval granuloma formation mediated by T lymphocytes is the key event triggering the formation of hepatic ...
Katsumi Maezawa   +4 more
doaj   +1 more source

Multi-omics analyses of Bacillus amyloliquefaciens treated mice infected with Schistosoma japonicum reveal dynamics change of intestinal microbiome and its associations with host metabolism.

open access: yesPLoS Neglected Tropical Diseases
BackgroundSchistosomiasis japonica is a serious threat to human health. It causes damage to the intestine and liver. Probiotic therapy has been shown to be effective in alleviating intestinal diseases and improving host health.
Hao Chen   +5 more
doaj   +1 more source

Characteristics of Intestinal Flora in Patients With Schistosoma japonicum Infection Undergoing Splenectomy

open access: yesParasite Immunology, Volume 47, Issue 5, May 2025.
ABSTRACT Schistosomiasis japonica is a parasitic disease that seriously endangers human health. Patients with advanced Schistosoma japonicum infection often suffer from cirrhosis and portal hypertension. Splenectomy has been widely used in the treatment of these patients. Previous studies have confirmed that S. japonicum infection is closely related to
Chen Zhou, Pengpeng Zhang, Yingzi Ming
wiley   +1 more source

Short-Term Efficacy of Laparoscopic Treatment for Colorectal Cancer in Patients with Schistosomiasis Japonica

open access: yesGastroenterology Research and Practice, 2016
Introduction. Schistosomiasis is associated with numerous complications such as thrombocytopenia, liver cirrhosis, portal hypertension, and colitis. To the best of our knowledge, the feasibility and outcomes of laparoscopic colorectal surgery in patients
Zhu Yi   +3 more
doaj   +1 more source

The N‐terminal domain of gasdermin D induces liver fibrosis by reprogrammed lipid metabolism

open access: yesAnimal Models and Experimental Medicine, Volume 8, Issue 1, Page 114-125, January 2025.
GSDMD‐NTki/wt × Alb‐creki/wt mice showed severe liver damage and hepatocyte vacuolation. The expression of genes involved in the development of liver fibrosis was stronger in the livers of GSDMD‐NTki/wtandAlb‐creki/wt mice. GSDMD‐NT induces fibrosis by mediating lipid metabolism. Abstract Background The emerging incidence of pathogenic liver conditions
Xue Wang   +10 more
wiley   +1 more source

Acute Appendicitis Secondary to Intestinal Schistosomiasis

open access: yesCase Reports in Surgery, Volume 2025, Issue 1, 2025.
Schistosomiasis is a parasitic disease caused by blood flukes commonly found in sub‐Saharan Africa and select other areas in Asia and the Americas. The disease can manifest in a wide range of acute and chronic conditions, rarely presenting as acute appendicitis.
Ethan Shyu   +5 more
wiley   +1 more source

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