Results 61 to 70 of about 93,083 (221)

Quantifying quality of life and disability of patients with advanced schistosomiasis japonica.

PLoS Neglected Tropical Diseases, 2011
BackgroundThe Chinese government lists advanced schistosomiasis as a leading healthcare priority due to its serious health and economic impacts, yet it has not been included in the estimates of schistosomiasis burden in the Global Burden of Disease (GBD)
Tie-Wu Jia, Jürg Utzinger, Yao Deng, Kun Yang, Yi-Yi Li, Jin-Huan Zhu, Charles H King, Xiao-Nong Zhou   +7 more
doaj   +1 more source

Therapeutic potential of fucoidan in the reduction of hepatic pathology in murine schistosomiasis japonica. [PDF]

Parasit Vectors, 2020
Background Hepatic granuloma formation and fibrosis as the consequence of tissue entrapped eggs produced by female schistosomes characterize the pathology of Schistosoma japonicum infection.
Bai X, Li M, Wang X, Chang H, Ni Y, Li C, He K, Wang H, Yang Y, Tian T, Hou M, Ji M, Xu Z.   +12 more
europepmc   +2 more sources

P21 activated kinase‐1 (PAK1) in macrophages is required for promotion of Th17 cell response during helminth infection

Journal of Cellular and Molecular Medicine, Volume 24, Issue 24, Page 14325-14338, December 2020., 2020
Abstract CD4+T cells differentiate into distinct functional effector and inhibitory subsets are facilitated by distinct cytokine cues present at the time of antigen recognition. Maintaining a balance between T helper 17 (Th17) and regulatory T (Treg) cells are critical for the control of the immunopathogenesis of liver diseases.
Hao Chang, Kai‐Yue He, Chen Li, Yang‐Yue Ni, Mai‐Ning Li, Lin Chen, Min Hou, Zikai Zhou, Zhi‐Peng Xu, Min‐Jun Ji   +9 more
wiley   +1 more source

Real-time PCR demonstrates high prevalence of Schistosoma japonicum in the Philippines: implications for surveillance and control. [PDF]

PLoS Neglected Tropical Diseases, 2015
BACKGROUND:The Philippines has a population of approximately 103 million people, of which 6.7 million live in schistosomiasis-endemic areas with 1.8 million people being at risk of infection with Schistosoma japonicum.
Catherine A Gordon, Luz P Acosta, Geoffrey N Gobert, Remigio M Olveda, Allen G Ross, Gail M Williams, Darren J Gray, Donald Harn, Yuesheng Li, Donald P McManus   +9 more
doaj   +1 more source

A comparison of modelling the spatio-temporal pattern of disease: a case study of schistosomiasis japonica in Anhui Province, China.

Transactions of the Royal Society of Tropical Medicine and Hygiene, 2021
The construction of spatio-temporal models can be either descriptive or dynamic. In this study we aim to evaluate the differences in model fitting between a descriptive model and a dynamic model of the transmission for intestinal schistosomiasis caused ...
Q. Su, R. Bergquist, Yongwen Ke, Ji-Ya Dai, Zonggui He, F. Gao, Zhijie Zhang, Yi Hu   +7 more
semanticscholar   +1 more source

Follicular helper T cells recruit eosinophils into host liver by producing CXCL12 during Schistosoma japonicum infection

Journal of Cellular and Molecular Medicine, Volume 24, Issue 4, Page 2566-2572, February 2020., 2020
Abstract Schistosomiasis affects at least 200 million people in tropical and subtropical areas. The major pathology of schistosomiasis is egg‐induced liver granuloma characterized by an eosinophil‐rich inflammatory infiltration around the eggs, which subsequently leads to hepatic fibrosis and circulatory impairment in host.
Xiaojun Chen, Zhipeng Xu, Chuan Wei, XiaoWei Yang, Lei Xu, Sha Zhou, Jifeng Zhu, Chuan Su   +7 more
wiley   +1 more source

A diagnostic challenge for schistosomiasis japonica in China: consequences on praziquantel-based morbidity control

Parasites & Vectors, 2011
Worldwide schistosomiasis continues to be a serious public health problem. Over the past five decades, China has made remarkable progress in reducing Schistosoma japonicum infections in humans to a relatively low level.
Zheng Hui-min, Zhou Yi-biao, Jiang Qing-wu   +2 more
doaj   +1 more source

Sedum sarmentosum Total Flavonoids Alleviate Schistosomiasis‐Induced Liver Fibrosis by Altering TGF‐β1 and Smad7 Expression

Evidence-Based Complementary and Alternative Medicine, Volume 2020, Issue 1, 2020., 2020
Objectives. Schistosomiasis is a parasitic disease that affects over 142 million people worldwide. The main causes of death of schistosomiasis include liver granuloma and secondary hepatic cirrhosis resulting from severe fibrosis. Despite intensive research, controlling liver fibrosis associated with schistosomiasis remains challenging.
Peng-chun Yang, Wei-zhe Bai, Jing Wang, Cai-hua Yan, Wei-feng Huang, Shi-zhu Jiang, Konrad Urech   +6 more
wiley   +1 more source

Long‐Term Traditional Chinese Medicine Combined with NA Antiviral Therapy on Cirrhosis Incidence in Chronic Hepatitis B Patients in the Real‐World Setting: A Retrospective Study

Evidence-Based Complementary and Alternative Medicine, Volume 2020, Issue 1, 2020., 2020
Objective. To evaluate the impact of long‐term Traditional Chinese Medicine (TCM) syndrome differentiation combined with antiviral therapy with Nucleos (t) ide analogues (NAs) on the incidence of cirrhosis in patients with chronic hepatitis B. Methods.
Zhi-Jun Hou, Jing-Hao Zhang, Xin Zhang, Qi-Hua Ling, Chao Zheng, Xiao-Jun Zhu, Zhen-Hua Zhou, Man Li, Xiao-Ni Kong, Xue-Hua Sun, Yue-Qiu Gao, Jian-Jie Chen, Maria G. Miguel   +12 more
wiley   +1 more source

Current Status of Schistosomiasis Control and Prospects for Elimination in the Dongting Lake Region of the People’s Republic of China

Frontiers in Immunology, 2020
Schistosomiasis japonica is an ancient parasitic disease that has severely impacted human health causing a substantial disease burden not only to the Chinese people but also residents of other countries such as the Philippines, Indonesia and, before the ...
Fei-Yue Li, Fei-Yue Li, Xun-Ya Hou, Hong-Zhuan Tan, Gail M. Williams, Darren J. Gray, Catherine A. Gordon, Johanna Kurscheid, Archie C. A. Clements, Archie C. A. Clements, Yue-Sheng Li, Yue-Sheng Li, Donald P. McManus   +12 more
doaj   +1 more source