Schistosomiasis remains a major global public health concern. Currently, the control of this neglected tropical disease still depends on chemotherapy to reduce the prevalence and intensity of the parasite infection. It has been widely accepted that praziquantel is highly effective against all species of Schistosoma, and this agent is virtually the only
Xuehua Niu+5 more
wiley +1 more source
Evaluation of a real-time PCR assay for diagnosis of schistosomiasis japonica in the domestic goat. [PDF]
Background Schistosomiasis japonica is an infectious disease caused by Schistosoma japonicum that seriously endangers human health. Domestic animals have important roles in disease transmission and goats are considered a primary reservoir host and source
Guo Q+12 more
europepmc +2 more sources
Activation of nuclear factor kappa B in the hepatic stellate cells of mice with schistosomiasis japonica. [PDF]
Schistosomiasis japonica is a serious tropical parasitic disease in humans, which causes inflammation and fibrosis of the liver. Hepatic stellate cells (HSCs) are known to play an important role in schistosome-induced fibrosis, but their role in ...
Xing He+4 more
doaj +1 more source
SCHISTOSOMIASIS JAPONICA AND “AUTOIMMUNITY”
Makoto Kurata
openalex +5 more sources
Higher frequency of circulating Vδ1 γδT cells in patients with advanced schistosomiasis
Abstract Gamma‐delta (γδ) T cells are the bridge between natural and adaptive immunity. In the present study, peripheral blood was collected from 13 patients with advanced schistosomiasis (schistosomiasis group) and 13 uninfected people (control group) to investigate the γδ T cells and their subtypes in human schistosomiasis.
Li Zheng+8 more
wiley +1 more source
IMMUNOLOGICAL STUDIES ON SCHISTOSOMIASIS JAPONICA
The changes in serum protein components of mice infected with Schistosoma japonicum were investigated by paper-electrophoresis.1) The examination of serum protein of mice infected with S. japonicum showed an increase of total protein in early infections (3 weeks after exposure to cereariae) raching the maximum 9 weeks after the infection, decrease in ...
S. Sato+5 more
openalex +4 more sources
Case Report: Multiple Schistosomiasis Japonica Cerebral Granulomas without Gastrointestinal System Involvement: Report of Two Cases and Review of Literature. [PDF]
Most schistosomiasis japonica cerebral granulomas reported in the literature have been single and located in the cerebellum, and multiple lesions located in the cerebral hemisphere are uncommon and often misdiagnosed as metastases or gliomas. We describe
Shen J, Yuan L, Sun Y, Jiang X, Shao X.
europepmc +2 more sources
Frontiers of parasitology research in the People's Republic of China : infection, diagnosis, protection and surveillance [PDF]
: Control and eventual elimination of human parasitic diseases in the People's Republic of China (P.R. China) requires novel approaches, particularly in the areas of diagnostics, mathematical modelling, monitoring, evaluation, surveillance and public ...
Bergquist, R.+6 more
core +2 more sources
Noninvasive diagnosis of liver fibrosis in schistosomiasis japonica: Opportunities and challenges
Portal Hypertension &Cirrhosis, Volume 2, Issue 1, Page 43-45, March 2023.
Tao Wang+4 more
wiley +1 more source
PAMAM-Lys, a novel vaccine delivery vector, enhances the protective effects of the SjC23 DNA vaccine against Schistosoma japonicum infection. [PDF]
BACKGROUND: Schistosomiasis japonica remains a major public-health concern in China. Praziquantel-based chemotherapy effectively reduces both infections and intensity; however, it can not prevent re-infection.
Xiaoting Wang+10 more
doaj +1 more source